Sprays are of great importance for many applications, with drop size being a crucial parameter. Especially in agriculture applications, simple flat fan spray nozzles are often supplemented by a Venturi component to achieve larger drop sizes and hence prevent un-wanted spray drift of the smallest droplets. The general believe is that these larger drops are usually attributed to the fact that the liquid sheet produced by the nozzle breaks up more easily due to the pre-existing ’holes’ formed by the induced air bubbles. Here, we extend descriptions of how nozzle and fluid parameters determine droplet size distributions from Venturi nozzles. We show that the mean droplet size is determined by the nozzle’s orifice area as is the case for ordinary flat fan nozzles but that the additional pressure drop over the Venturi chamber needs to be taken into account. Using this parameter, relations that were derived for flat fan nozzles can be re-used. This allows to show that the increase in droplet size compared to conventional nozzles is due to the additional pressure drop in the Venturi chamber, and not to a change in breakup mechanism due to the presence of air bubbles in the liquid sheet.