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Research Article
Eiichiro Nakamura
University of Occupational and Environmental Health Japan
Corresponding Author
License:
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We investigated longitudinal losses of paraspinal muscle area in healthy individuals in a 10-year longitudinal retrospective observational study. Data from 1,849 individuals (1,690 men, 159 women) screened using computed tomography were examined. Logistic regression was performed to determine risk factors associated with paraspinal muscle area decreases; the area was significantly decreased at 10 years compared with the area at baseline regardless of age or sex, starting at 30 years of age. In regression analysis, only aging (≥50s [odds ratio [OR], 1.72; 95% confidence interval [CI], 1.05–2.84; p=0.03] and ≥60s [OR, 2.67; 95% CI, 1.55–4.60; p<0.001]) was a risk factor for psoas major area decreases. Age ≥60 years (OR, 2.05; 95% CI, 1.24–3.39; p=0.005), body mass index ≥25 kg/m2 (OR, 1.32; 95% CI, 1.01–1.73; p=0.04), and visceral fat ≥100 cm2 (OR, 1.61; 95% CI, 1.20–2.15; p=0.001) were risk factors for erector muscle area decreases; physical activity ≥900 kcal/week (OR, 0.68; 95% CI, 0.50–0.94; p=0.02) reduced erector muscle area loss in males. Our study demonstrated that walking >45 minutes daily could reduce paraspinal muscle loss, which in turn can decrease the risk of falls and low-back pain and might eventually help prevent sarcopenia.
Keywords
Risk Factors, Paraspinal Muscle, Longitudinal
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No competing interests reported.
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View the published article at Scientific Reports.
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A new preprint design is coming!
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See the published version of this preprint at Scientific Reports.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Eiichiro Nakamura
University of Occupational and Environmental Health Japan
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at Scientific Reports.
Version 1
Posted 16 Feb, 2021
No community comments so far
Editorial decision: Major revision
On 26 Apr, 2021
Reviews received
Received 11 Apr, 2021
Reviewers agreed
On 10 Apr, 2021
Reviewers agreed
On 29 Mar, 2021
Reviewers invited
Invitations sent on 27 Mar, 2021
Editor assigned
On 23 Mar, 2021
Editor invited
On 05 Feb, 2021
Submission checks complete
On 05 Feb, 2021
First submitted
On 31 Jan, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at Scientific Reports.
We investigated longitudinal losses of paraspinal muscle area in healthy individuals in a 10-year longitudinal retrospective observational study. Data from 1,849 individuals (1,690 men, 159 women) screened using computed tomography were examined. Logistic regression was performed to determine risk factors associated with paraspinal muscle area decreases; the area was significantly decreased at 10 years compared with the area at baseline regardless of age or sex, starting at 30 years of age. In regression analysis, only aging (≥50s [odds ratio [OR], 1.72; 95% confidence interval [CI], 1.05–2.84; p=0.03] and ≥60s [OR, 2.67; 95% CI, 1.55–4.60; p<0.001]) was a risk factor for psoas major area decreases. Age ≥60 years (OR, 2.05; 95% CI, 1.24–3.39; p=0.005), body mass index ≥25 kg/m2 (OR, 1.32; 95% CI, 1.01–1.73; p=0.04), and visceral fat ≥100 cm2 (OR, 1.61; 95% CI, 1.20–2.15; p=0.001) were risk factors for erector muscle area decreases; physical activity ≥900 kcal/week (OR, 0.68; 95% CI, 0.50–0.94; p=0.02) reduced erector muscle area loss in males. Our study demonstrated that walking >45 minutes daily could reduce paraspinal muscle loss, which in turn can decrease the risk of falls and low-back pain and might eventually help prevent sarcopenia.
Figure 1
Figure 2
Figure 3
No competing interests reported.
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