In 2016, air pollution from oil & gas (O&G) production in the U.S. resulted in 7,500 (95% CI: 4,500 - 12,000) excess deaths among many other health impacts, valued at $77 billion ($2016 USD) (95% CI: $27 billion - $170 billion). An ambitious methane reduction policy in 2028 would result in 1,400 (820 - 2,300) deaths compared to 2028 business as usual, while other policies would have modest effects. Regions without O&G activity experienced impact from the sector and benefits from emissions reductions. On a per ton basis, the health co-benefits per methane reduction from each policy were ~5x lower than health co-impacts from the whole production sector, since policies only apply to specific O&G production processes. We show that there are still substantial health co-benefits to policies that reduce methane emissions, however the health co-benefits can be enhanced if emissions reduction policies cover more components of O&G production.