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Original Article
Ana João Silva Costa
Centro de Reabilitação do Norte
Corresponding Author
ORCiD: https://orcid.org/0000-0002-3460-8968
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Purpose: Functional capacity (FC) declining has been poorly evaluated and characterized in women with breast cancer (BC). It is expected that FC declining may have an impact on survival, and also compromise quality of life and independence. This study aimed to evaluate the FC of women with BC and identify predictors of obtained results.
Methods: A cross-sectional study including women with BC consecutively referred for a physical medicine and rehabilitation consult between October and December 2019. Glittre-ADL Test (TGlittre), maximal respiratory pressure tests [maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP)] and Modified Fatigue Impact Scale were used in order to assess FC, respiratory muscle strength and fatigue, respectively. Age, professional status, smoking habits, comorbidities, body mass index, duration and status of disease, previous and ongoing treatments were also registered.
Results: A total of 42 women with non-metastatic BC were enrolled with a disease duration of 11.50 months (71), mostly in stage II (53.60%) and under hormone therapy (38.10%). TGlittre performance time was 3.13 minutes (8.72). TGlittre performance time correlated with MIP (r = -0.373; p <0.01) and MEP (r = -0.414; p = 0.007) values and age (r = 0.711; p < 0.010). Patients with CV and endocrine comorbidities had higher TGlittre time values (p <0.01 and p = 0.019, respectively). Age was the only statistically significant predictor (p=0.041) of TGlittre variation.
Conclusions: Women with BC presented decreased FC with mean values of TGlittre duration higher than those described in the literature in healthy subjects.
Keywords
Activities of Daily Living, Breast Cancer, Disability, Rehabilitation, Respiratory Muscles
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A new preprint design is coming!
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Original Article
Ana João Silva Costa
Centro de Reabilitação do Norte
Corresponding Author
ORCiD: https://orcid.org/0000-0002-3460-8968
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 15 Feb, 2021
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Cancer Biology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Purpose: Functional capacity (FC) declining has been poorly evaluated and characterized in women with breast cancer (BC). It is expected that FC declining may have an impact on survival, and also compromise quality of life and independence. This study aimed to evaluate the FC of women with BC and identify predictors of obtained results.
Methods: A cross-sectional study including women with BC consecutively referred for a physical medicine and rehabilitation consult between October and December 2019. Glittre-ADL Test (TGlittre), maximal respiratory pressure tests [maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP)] and Modified Fatigue Impact Scale were used in order to assess FC, respiratory muscle strength and fatigue, respectively. Age, professional status, smoking habits, comorbidities, body mass index, duration and status of disease, previous and ongoing treatments were also registered.
Results: A total of 42 women with non-metastatic BC were enrolled with a disease duration of 11.50 months (71), mostly in stage II (53.60%) and under hormone therapy (38.10%). TGlittre performance time was 3.13 minutes (8.72). TGlittre performance time correlated with MIP (r = -0.373; p <0.01) and MEP (r = -0.414; p = 0.007) values and age (r = 0.711; p < 0.010). Patients with CV and endocrine comorbidities had higher TGlittre time values (p <0.01 and p = 0.019, respectively). Age was the only statistically significant predictor (p=0.041) of TGlittre variation.
Conclusions: Women with BC presented decreased FC with mean values of TGlittre duration higher than those described in the literature in healthy subjects.
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