Suicide is a serious global public health problem. More than 700,000 people worldwide commit suicide each year, and suicide is the fourth leading cause of death among people aged 15–29 years [1]. Suicide rates in China have continued to decline (from 2002 to 2015), but suicide is still a concern [2, 3]. The process of suicide in individuals generally goes through three stages: developing suicidal ideation, making a suicide plan, and committing suicidal acts [4]. According to the interpersonal theory of suicide, an individual will only commit suicide if he or she has the following: a sense of unmet belonging, a sense of perceived burdensomeness and the ability to commit suicide. Additionally, he or she is highly vulnerable to suicidal ideation when both unmet belonging and perceived burdensomeness are present, but both are not stable traits and are susceptible to interpersonal factors and the individual's early experiences[5]. Suicide is a behavior initiated by suicidal ideation, and although having suicidal thoughts without actually committing suicide, suicidal ideation provides the individual with an opportunity to reexamine the meaning of life and is an important predictor of suicidal behavior factors[4, 6].Therefore, it is important to understand the characteristics of suicidal ideation and to develop targeted prevention and intervention approaches to reduce the occurrence of suicidal ideation.
Globally, the college student population has high levels of suicidal ideation, planning, and attempts [7–9]. As college students move from adolescence into early adulthood, they are faced with multiple pressures from performing in academics, developing a sense of self-identity, maintaining interpersonal relationships, and planning for a career. Medical students are a special group with a higher incidence of mental health problems than the general population [10]. Long hours of study, heavy academic loads, competition with peers and other stressors can affect the mental health of medical students [11, 12] and lead to high levels of suicidal ideation [10, 13]. The common view is that suicidal ideation is a fleeting thought; however, longitudinal findings found that 16% of those who reported suicidal ideation at baseline levels still reported suicidal ideation at follow-up 9 years later, meaning that there is a persistent effect of suicidal ideation [14]. The same results were confirmed in the adolescent population [15]. There is no consensus on the characteristics of the trajectory of suicidal ideation, with findings indicating that suicidal ideation fluctuates widely across seven time points [16]. There are three types of trajectories of suicidal ideation: low level-stable, high level-declining, and a moderate level that is either declining or rising [17]. However, another follow-up study showed no change in the overall level of suicidal ideation among Chinese adolescents [18]. There is no research on the development of suicidal ideation among medical students, so is there a unique trajectory of suicidal ideation among this unique student population?
The cumulative situational risk model suggests that the more negative situations an individual experiences early in life, the higher the likelihood of cumulative or superimposed developmental risk and the greater the risk of suicidal ideation [19]. Among the negative situations that lead to suicidal ideation, childhood trauma is a significant predictor. Childhood trauma is defined as actual or potential harm to a child's health, survival, development or self-esteem by the child's guardian or someone the child trusts and includes various forms of emotional abuse, physical abuse, sexual abuse, neglect, and commercial exploitation [20]. Individuals who have been abused in childhood have a high frequency of suicidal thinking and suicide attempts, and will encounter more difficulties in the subsequent development tasks, showing more depression, suicidal ideation and suicide attempts[21–23]. Although most studies confirm the strong relationship between childhood abuse and suicidal ideation and suicidal behaviour, some studies have found that only childhood sexual abuse directly affects suicidal ideation[24]. It has also been shown that childhood maltreatment, such as physical and emotional abuse, does not effectively predict suicidal ideation [25] and that some individuals maltreated in childhood have relatively lower suicidal ideation [26, 27]. Based on previous research, the relationship between childhood maltreatment and suicidal ideation is uncertain, but childhood maltreatment has a cumulative negative impact and is associated with the development of negative emotions and behaviours in individuals. This study therefore seeks to understand whether different forms of childhood maltreatment over time affect changes in suicidal ideation.
The COVID-19 epidemic has led adolescents to develop negative emotions such as anxiety, depression and even suicidal ideation [28–30]. During the pandemic, severe suicidal ideation was most common among 18- to 24-year-olds [31],and the total number of suicidal ideations increased by almost 63.3% [32]. A total of 36.4% of rural Chinese high school students reported suicidal ideation during the COVID-19 pandemic [33]. Although many studies have confirmed that the COVID-19 epidemic affects suicidal ideation among college students, the impact on suicidal ideation among Chinese medical students is elusive.
In summary, most of the existing studies on suicidal ideation are cross-sectional surveys, which do not well reflect developmental characteristics and trends in suicidal ideation. The few longitudinal studies on suicidal ideation have only described simple outcomes and have not examined trends and changes in suicidal ideation, nor have they explored group heterogeneity. While studies on factors influencing suicidal ideation generally support the association of gender, place of origin, major, and childhood maltreatment with suicidal ideation, there are a few studies with different results, and the use of longitudinal follow-up studies and exploration of heterogeneity would be more effective in clarifying the relationship of these studies to the mainstream. Therefore, this study uses a latent variable mixed growth model with medical students to first explore the trajectory of suicidal ideation among college students and whether there are heterogeneous latent category differences and second, to further understand the predictive effects of gender, place of birth, major, and childhood maltreatment on the trajectory of suicidal ideation among college students. In this study, we aim to enrich existing theories and provide references for the prevention of suicide among medical students.