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Research
Estimation of losses of quality-adjusted life expectancy attributed to the combination of cognitive impairment and multimorbidity among Chinese adults aged 45 years and older
Yueping Shen
Corresponding Author
ORCiD: https://orcid.org/0000-0002-6304-4188
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Objectives: This study aims to estimate the losses of quality-adjusted life expectancy (QALE) due to the joint effect of cognitive impairment and multimorbidity, and further to confirm additional losses attributable to their interaction among the middle-aged and elderly Chinese.
Methods: The National Cause of Death Monitoring Data were linked with the China Health and Retirement Longitudinal Study (CHARLS). A mapping and assigning method was used to estimate health utility values, which were further used to calculate QALE. Losses of QALE were measured by comparing the differences between subgroups. And all the losses of QALE were displayed at two levels: the individual and the population level.
Results: At age 45, the individual-level and population-level losses of QALE (95% CI) attributed to the combination of cognitive impairment and multimorbidity were 7.606 (5.679, 9.566) years and 4.297 (3.425, 5.200) years. The losses (95% CI) for cognitive impairment alone were 3.104 (2.287, 3.954) years and 1.709 (1.318, 2.132) years at two levels. Similarly, the losses (95% CI) for multimorbidity alone were 3.526 (2.528, 4.556) years and 1.914 (1.235, 2.625) years at two levels. Additional losses due to their interaction were indicated by the 0.976 years of the individual-level gap and 0.674 years of the population-level gap.
Conclusion: Among the middle-aged and elderly Chinese, cognitive impairment and multimorbidity resulted in much losses of QALE, and additional QALE losses were seen due to their interaction at both individual and population levels.
Keywords
Quality-adjusted life expectancy, cognitive impairment, multimorbidity, CHARLS
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Research
Estimation of losses of quality-adjusted life expectancy attributed to the combination of cognitive impairment and multimorbidity among Chinese adults aged 45 years and older
Yueping Shen
Corresponding Author
ORCiD: https://orcid.org/0000-0002-6304-4188
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 12 Apr, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Health Economics & Outcomes Research
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Objectives: This study aims to estimate the losses of quality-adjusted life expectancy (QALE) due to the joint effect of cognitive impairment and multimorbidity, and further to confirm additional losses attributable to their interaction among the middle-aged and elderly Chinese.
Methods: The National Cause of Death Monitoring Data were linked with the China Health and Retirement Longitudinal Study (CHARLS). A mapping and assigning method was used to estimate health utility values, which were further used to calculate QALE. Losses of QALE were measured by comparing the differences between subgroups. And all the losses of QALE were displayed at two levels: the individual and the population level.
Results: At age 45, the individual-level and population-level losses of QALE (95% CI) attributed to the combination of cognitive impairment and multimorbidity were 7.606 (5.679, 9.566) years and 4.297 (3.425, 5.200) years. The losses (95% CI) for cognitive impairment alone were 3.104 (2.287, 3.954) years and 1.709 (1.318, 2.132) years at two levels. Similarly, the losses (95% CI) for multimorbidity alone were 3.526 (2.528, 4.556) years and 1.914 (1.235, 2.625) years at two levels. Additional losses due to their interaction were indicated by the 0.976 years of the individual-level gap and 0.674 years of the population-level gap.
Conclusion: Among the middle-aged and elderly Chinese, cognitive impairment and multimorbidity resulted in much losses of QALE, and additional QALE losses were seen due to their interaction at both individual and population levels.
Figure 1
Figure 2
Figure 3
Due to technical limitations, full-text HTML conversion of this manuscript could not be completed. However, the manuscript can be downloaded and accessed as a PDF.