1 Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a cancer journal for clinicians. 2018; 68(6): 394-424. https://doi.org/10.3322/caac.21492.
2 Cronin KA, Lake AJ, Scott S, Sherman RL, Noone A-M, Howlader N, Henley SJ, Anderson RN, Firth AU, Ma J, Kohler BA, Jemal A. Annual Report to the Nation on the Status of Cancer, part I: National cancer statistics. Cancer. 2018; 124(13): 2785-2800. https://doi.org/10.1002/cncr.31551.
3 Choi AH, Kim J, Chao J. Perioperative chemotherapy for resectable gastric cancer: MAGIC and beyond. World J Gastroenterol. 2015; 21(24): 7343-7348. https://doi.org/10.3748/wjg.v21.i24.7343.
4 Hu Y, Huang C, Sun Y, Su X, Cao H, Hu J, Xue Y, Suo J, Tao K, He X, Wei H, Ying M, Hu W, Du X, Chen P, Liu H, Zheng C, Liu F, Yu J, Li Z, Zhao G, Chen X, Wang K, Li P, Xing J, Li G. Morbidity and Mortality of Laparoscopic Versus Open D2 Distal Gastrectomy for Advanced Gastric Cancer: A Randomized Controlled Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 2016; 34(12): 1350-1357. https://doi.org/10.1200/JCO.2015.63.7215.
5 Yu J, Huang C, Sun Y, Su X, Cao H, Hu J, Wang K, Suo J, Tao K, He X, Wei H, Ying M, Hu W, Du X, Hu Y, Liu H, Zheng C, Li P, Xie J, Liu F, Li Z, Zhao G, Yang K, Liu C, Li H, Chen P, Ji J, Li G, Chinese Laparoscopic Gastrointestinal Surgery Study G. Effect of Laparoscopic vs Open Distal Gastrectomy on 3-Year Disease-Free Survival in Patients With Locally Advanced Gastric Cancer: The CLASS-01 Randomized Clinical Trial. JAMA. 2019; 321(20): 1983-1992. https://doi.org/10.1001/jama.2019.5359.
6 Orr GA, Verdier-Pinard P, McDaid H, Horwitz SB. Mechanisms of Taxol resistance related to microtubules. Oncogene. 2003; 22(47): 7280-7295. https://doi.org/10.1038/sj.onc.1206934.
7 Sangrajrang S, Fellous A. Taxol resistance. Chemotherapy. 2000; 46(5): 327-334. https://doi.org/10.1159/000007306.
8 Xu MS, Yang GX, Bi HT, Xu JT, Dong SM, Jia T, Wang Z, Zhao RX, Sun QQ, Gai SL, He F, Yang D, Yang PP. An intelligent nanoplatform for imaging-guided photodynamic/photothermal/chemo-therapy based on upconversion nanoparticles and CuS integrated black phosphorus. Chemical Engineering Journal. 2020; 382: 12. https://doi.org/10.1016/j.cej.2019.122822.
9 Guo W, Deng L, Chen Z, Chen Z, Yu J, Liu H, Li T, Lin T, Chen H, Zhao M, Zhang L, Li G, Hu Y. Vitamin B12-conjugated sericin micelles for targeting CD320-overexpressed gastric cancer and reversing drug resistance. Nanomedicine (London, England). 2019; 14(3): 353-370. https://doi.org/10.2217/nnm-2018-0321.
10 Liu Z, Robinson JT, Sun X, Dai H. PEGylated nanographene oxide for delivery of water-insoluble cancer drugs. Journal of the American Chemical Society. 2008; 130(33): 10876-10877. https://doi.org/10.1021/ja803688x.
11 Bao H, Pan Y, Ping Y, Sahoo NG, Wu T, Li L, Li J, Gan LH. Chitosan-functionalized graphene oxide as a nanocarrier for drug and gene delivery. Small (Weinheim an der Bergstrasse, Germany). 2011; 7(11): 1569-1578. https://doi.org/10.1002/smll.201100191.
12 Jiang X, Ruan G, Huang Y, Chen Z, Yuan H, Du F. Assembly and application advancement of organic-functionalized graphene-based materials: A review. Journal of separation science. 2020: 10.1002/jssc.201900694. https://doi.org/10.1002/jssc.201900694.
13 Xia YP, Zhang HZ, Huang PR, Huang CW, Xu F, Zou YJ, Chu HL, Yan EH, Sun LX. Graphene-oxide-induced lamellar structures used to fabricate novel composite solid-solid phase change materials for thermal energy storage. Chemical Engineering Journal. 2019; 362: 909-920. https://doi.org/10.1016/j.cej.2019.01.097.
14 Feng X, Chen L, Guo W, Zhang Y, Lai X, Shao L, Li Y. Graphene oxide induces p62/SQSTM-dependent apoptosis through the impairment of autophagic flux and lysosomal dysfunction in PC12 cells. Acta biomaterialia. 2018; 81: 278-292. https://doi.org/10.1016/j.actbio.2018.09.057.
15 Geetha Bai R, Muthoosamy K, Shipton FN, Manickam S. Acoustic cavitation induced generation of stabilizer-free, extremely stable reduced graphene oxide nanodispersion for efficient delivery of paclitaxel in cancer cells. Ultrasonics sonochemistry. 2017; 36: 129-138. https://doi.org/10.1016/j.ultsonch.2016.11.021.
16 Jia J, Wang CX, Chen KL, Yin YJ. Drug release of yolk/shell microcapsule controlled by pH-responsive yolk swelling. Chemical Engineering Journal. 2017; 327: 953-961. https://doi.org/10.1016/j.cej.2017.06.170.
17 Gao C, Tang F, Gong G, Zhang J, Hoi MPM, Lee SMY, Wang R. pH-Responsive prodrug nanoparticles based on a sodium alginate derivative for selective co-release of doxorubicin and curcumin into tumor cells. Nanoscale. 2017; 9(34): 12533-12542. https://doi.org/10.1039/c7nr03611f.
18 Mu B, Lu C, Liu P. Disintegration-controllable stimuli-responsive polyelectrolyte multilayer microcapsules via covalent layer-by-layer assembly. Colloids Surf B Biointerfaces. 2011; 82(2): 385-390. https://doi.org/10.1016/j.colsurfb.2010.09.024.
19 Wang L, Zhou W, Wang Q, Xu C, Tang Q, Yang H. An Injectable, Dual Responsive, and Self-Healing Hydrogel Based on Oxidized Sodium Alginate and Hydrazide-Modified Poly(ethyleneglycol). Molecules. 2018; 23(3). https://doi.org/10.3390/molecules23030546.
20 He YC, Cong C, Liu ZW, Li XL, Zhu RY, Gao DW. Stealth surface driven accumulation of "Trojan Horse" for tumor hypoxia relief in combination with targeted cancer therapy. Chemical Engineering Journal. 2019; 378: 8. https://doi.org/10.1016/j.cej.2019.122252.
21 Li H, Liu C, Zeng YP, Hao YH, Huang JW, Yang ZY, Li R. Nanoceria-Mediated Drug Delivery for Targeted Photodynamic Therapy on Drug-Resistant Breast Cancer. ACS Appl Mater Interfaces. 2016; 8(46): 31510-31523. https://doi.org/10.1021/acsami.6b07338.
22 Wang M, Xiao Y, Li Y, Wu J, Li F, Ling D, Gao J. Reactive oxygen species and near-infrared light dual-responsive indocyanine green-loaded nanohybrids for overcoming tumour multidrug resistance. Eur J Pharm Sci. 2019; 134: 185-193. https://doi.org/10.1016/j.ejps.2019.04.021.
23 Li Q, Hong L, Li H, Liu C. Graphene oxide-fullerene C(60) (GO-C(60)) hybrid for photodynamic and photothermal therapy triggered by near-infrared light. Biosens Bioelectron. 2017; 89(Pt 1): 477-482. https://doi.org/10.1016/j.bios.2016.03.072.
24 Sun J, Song L, Fan Y, Tian L, Luan S, Niu S, Ren L, Ming W, Zhao J. Synergistic Photodynamic and Photothermal Antibacterial Nanocomposite Membrane Triggered by Single NIR Light Source. ACS Appl Mater Interfaces. 2019; 11(30): 26581-26589. https://doi.org/10.1021/acsami.9b07037.
25 Gao S, Zhang L, Wang G, Yang K, Chen M, Tian R, Ma Q, Zhu L. Hybrid graphene/Au activatable theranostic agent for multimodalities imaging guided enhanced photothermal therapy. Biomaterials. 2016; 79: 36-45. https://doi.org/10.1016/j.biomaterials.2015.11.041.
26 Liao GF, He F, Li Q, Zhong L, Zhao RZ, Che HN, Gao HY, Fang BZ. Emerging graphitic carbon nitride-based materials for biomedical applications. Progress in Materials Science. 2020; 112: 21. https://doi.org/10.1016/j.pmatsci.2020.100666.
27 Le-Tien C, Millette M, Lacroix M, Mateescu M-A. Modified alginate matrices for the immobilization of bioactive agents. Biotechnology and applied biochemistry. 2004; 39(Pt 2): 189-198. https://doi.org/10.1042/BA20030054.
28 Sun X, Zebibula A, Dong X, Zhang G, Zhang D, Qian J, He S. Aggregation-Induced Emission Nanoparticles Encapsulated with PEGylated Nano Graphene Oxide and Their Applications in Two-Photon Fluorescence Bioimaging and Photodynamic Therapy in Vitro and in Vivo. ACS applied materials & interfaces. 2018; 10(30): 25037-25046. https://doi.org/10.1021/acsami.8b05546.
29 Sun J, Tan H. Alginate-Based Biomaterials for Regenerative Medicine Applications. Materials (Basel). 2013; 6(4): 1285-1309. https://doi.org/10.3390/ma6041285.
30 Yao W, Wang J, Wang P, Wang X, Yu S, Zou Y, Hou J, Hayat T, Alsaedi A, Wang X. Synergistic coagulation of GO and secondary adsorption of heavy metal ions on Ca/Al layered double hydroxides. Environmental pollution (Barking, Essex : 1987). 2017; 229: 827-836. https://doi.org/10.1016/j.envpol.2017.06.084.
31 Wilfong WC, Kail BW, Bank TL, Howard BH, Gray ML. Recovering Rare Earth Elements from Aqueous Solution with Porous Amine-Epoxy Networks. ACS applied materials & interfaces. 2017; 9(21): 18283-18294. https://doi.org/10.1021/acsami.7b03859.
32 Almeida A, Silva D, Gonçalves V, Sarmento B. Synthesis and characterization of chitosan-grafted-polycaprolactone micelles for modulate intestinal paclitaxel delivery. Drug delivery and translational research. 2018; 8(2): 387-397. https://doi.org/10.1007/s13346-017-0357-8.
33 Luiz MT, Abriata JP, Raspantini GL, Tofani LB, Fumagalli F, de Melo SMG, Emery FdS, Swiech K, Marcato PD, Lee R, Marchetti JM. In vitro evaluation of folate-modified PLGA nanoparticles containing paclitaxel for ovarian cancer therapy. Materials science & engineering. C, Materials for biological applications. 2019; 105: 110038-110038. https://doi.org/10.1016/j.msec.2019.110038.
34 Chiang M-Y, Lin Y-Z, Chang S-J, Shyu W-C, Lu H-E, Chen S-Y. Direct Reprogramming of Human Suspension Cells into Mesodermal Cell Lineages via Combined Magnetic Targeting and Photothermal Stimulation by Magnetic Graphene Oxide Complexes. Small (Weinheim an der Bergstrasse, Germany). 2017; 13(32): 10.1002/smll.201700703. https://doi.org/10.1002/smll.201700703.
35 Liu W, Zhang X, Zhou L, Shang L, Su Z. Reduced graphene oxide (rGO) hybridized hydrogel as a near-infrared (NIR)/pH dual-responsive platform for combined chemo-photothermal therapy. Journal of colloid and interface science. 2019; 536: 160-170. https://doi.org/10.1016/j.jcis.2018.10.050.
36 Deng R-H, Zou M-Z, Zheng D, Peng S-Y, Liu W, Bai X-F, Chen H-S, Sun Y, Zhou P-H, Zhang X-Z. Nanoparticles from Cuttlefish Ink Inhibit Tumor Growth by Synergizing Immunotherapy and Photothermal Therapy. ACS nano. 2019; 13(8): 8618-8629. https://doi.org/10.1021/acsnano.9b02993.
37 Zhang D, Wei L, Zhong M, Xiao L, Li H-W, Wang J. The morphology and surface charge-dependent cellular uptake efficiency of upconversion nanostructures revealed by single-particle optical microscopy. Chemical science. 2018; 9(23): 5260-5269. https://doi.org/10.1039/c8sc01828f.
38 Tran A-V, Shim K, Vo Thi T-T, Kook J-K, An SSA, Lee S-W. Targeted and controlled drug delivery by multifunctional mesoporous silica nanoparticles with internal fluorescent conjugates and external polydopamine and graphene oxide layers. Acta biomaterialia. 2018; 74: 397-413. https://doi.org/10.1016/j.actbio.2018.05.022.
39 Zhao X, Liu L, Li X, Zeng J, Jia X, Liu P. Biocompatible graphene oxide nanoparticle-based drug delivery platform for tumor microenvironment-responsive triggered release of doxorubicin. Langmuir : the ACS journal of surfaces and colloids. 2014; 30(34): 10419-10429. https://doi.org/10.1021/la502952f.
40 Huang J, Zong C, Shen H, Liu M, Chen B, Ren B, Zhang Z. Mechanism of cellular uptake of graphene oxide studied by surface-enhanced Raman spectroscopy. Small (Weinheim an der Bergstrasse, Germany). 2012; 8(16): 2577-2584. https://doi.org/10.1002/smll.201102743.
41 Merrifield CJ, Kaksonen M. Endocytic accessory factors and regulation of clathrin-mediated endocytosis. Cold Spring Harbor perspectives in biology. 2014; 6(11): a016733-a016733. https://doi.org/10.1101/cshperspect.a016733.
42 Mayor S, Pagano RE. Pathways of clathrin-independent endocytosis. Nature reviews. Molecular cell biology. 2007; 8(8): 603-612. https://doi.org/10.1038/nrm2216.
43 Zhang C, Shi G, Zhang J, Niu J, Huang P, Wang Z, Wang Y, Wang W, Li C, Kong D. Redox- and light-responsive alginate nanoparticles as effective drug carriers for combinational anticancer therapy. Nanoscale. 2017; 9(9): 3304-3314. https://doi.org/10.1039/c7nr00005g.
44 Mead TJ, Lefebvre V. Proliferation assays (BrdU and EdU) on skeletal tissue sections. Methods in molecular biology (Clifton, N.J.). 2014; 1130: 233-243. https://doi.org/10.1007/978-1-62703-989-5_17.
45 Porter AG, Jänicke RU. Emerging roles of caspase-3 in apoptosis. Cell death and differentiation. 1999; 6(2): 99-104. https://doi.org/10.1038/sj.cdd.4400476.
46 Feng L, Dong Z, Tao D, Zhang Y, Liu Z. The acidic tumor microenvironment: a target for smart cancer nano-theranostics. National Science Review. 2017; 5(2): 269-286. https://doi.org/10.1093/nsr/nwx062.
47 Zhang X, Xi Z, Machuki JO, Luo J, Yang D, Li J, Cai W, Yang Y, Zhang L, Tian J, Guo K, Yu Y, Gao F. Gold Cube-in-Cube Based Oxygen Nanogenerator: A Theranostic Nanoplatform for Modulating Tumor Microenvironment for Precise Chemo-Phototherapy and Multimodal Imaging. ACS Nano. 2019; 13(5): 5306-5325. https://doi.org/10.1021/acsnano.8b09786.
48 Huang J, Huang Y, Xue Z, Zeng S. Tumor microenvironment responsive hollow mesoporous Co(9)S(8)@MnO(2)-ICG/DOX intelligent nanoplatform for synergistically enhanced tumor multimodal therapy. Biomaterials. 2020; 262: 120346. https://doi.org/10.1016/j.biomaterials.2020.120346.
49 Gottesman MM, Fojo T, Bates SE. Multidrug resistance in cancer: role of ATP-dependent transporters. Nature reviews. Cancer. 2002; 2(1): 48-58. https://doi.org/10.1038/nrc706.
50 Li W, Zhang H, Assaraf YG, Zhao K, Xu X, Xie J, Yang D-H, Chen Z-S. Overcoming ABC transporter-mediated multidrug resistance: Molecular mechanisms and novel therapeutic drug strategies. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy. 2016; 27: 14-29. https://doi.org/10.1016/j.drup.2016.05.001.
51 Ding Y, Du C, Qian J, Dong C-M. NIR-Responsive Polypeptide Nanocomposite Generates NO Gas, Mild Photothermia, and Chemotherapy to Reverse Multidrug-Resistant Cancer. Nano letters. 2019; 19(7): 4362-4370. https://doi.org/10.1021/acs.nanolett.9b00975.
52 Yang G, Tian J, Chen C, Jiang D, Xue Y, Wang C, Gao Y, Zhang W. An oxygen self-sufficient NIR-responsive nanosystem for enhanced PDT and chemotherapy against hypoxic tumors. Chemical science. 2019; 10(22): 5766-5772. https://doi.org/10.1039/c9sc00985j.
53 Szakács G, Paterson JK, Ludwig JA, Booth-Genthe C, Gottesman MM. Targeting multidrug resistance in cancer. Nature reviews. Drug discovery. 2006; 5(3): 219-234. https://doi.org/10.1038/nrd1984.
54 Klingenberg M. The ADP-ATP translocation in mitochondria, a membrane potential controlled transport. The Journal of membrane biology. 1980; 56(2): 97-105. https://doi.org/10.1007/bf01875961.
55 Ahn CS, Metallo CM. Mitochondria as biosynthetic factories for cancer proliferation. Cancer & metabolism. 2015; 3(1): 1-1. https://doi.org/10.1186/s40170-015-0128-2.
56 Lusvarghi S, Ambudkar SV. ATP-dependent thermostabilization of human P-glycoprotein (ABCB1) is blocked by modulators. The Biochemical journal. 2019; 476(24): 3737-3750. https://doi.org/10.1042/BCJ20190736.
57 Letts JA, Sazanov LA. Clarifying the supercomplex: the higher-order organization of the mitochondrial electron transport chain. Nature structural & molecular biology. 2017; 24(10): 800-808. https://doi.org/10.1038/nsmb.3460.
58 Balsa E, Marco R, Perales-Clemente E, Szklarczyk R, Calvo E, Landázuri MO, Enríquez JA. NDUFA4 is a subunit of complex IV of the mammalian electron transport chain. Cell metabolism. 2012; 16(3): 378-386. https://doi.org/10.1016/j.cmet.2012.07.015.
59 Zhao R-Z, Jiang S, Zhang L, Yu Z-B. Mitochondrial electron transport chain, ROS generation and uncoupling (Review). International journal of molecular medicine. 2019; 44(1): 3-15. https://doi.org/10.3892/ijmm.2019.4188.
60 Murphy MP. How mitochondria produce reactive oxygen species. The Biochemical journal. 2009; 417(1): 1-13. https://doi.org/10.1042/BJ20081386.
61 Bhandary B, Marahatta A, Kim H-R, Chae H-J. An involvement of oxidative stress in endoplasmic reticulum stress and its associated diseases. International journal of molecular sciences. 2012; 14(1): 434-456. https://doi.org/10.3390/ijms14010434.
62 Loreto C, La Rocca G, Anzalone R, Caltabiano R, Vespasiani G, Castorina S, Ralph DJ, Cellek S, Musumeci G, Giunta S, Djinovic R, Basic D, Sansalone S. The role of intrinsic pathway in apoptosis activation and progression in Peyronie's disease. BioMed research international. 2014; 2014: 616149-616149. https://doi.org/10.1155/2014/616149.
63 He F, Ji HJ, Feng LL, Wang Z, Sun QQ, Zhong CN, Yang D, Gai SL, Yang PP, Lin J. Construction of thiol-capped ultrasmall Au-Bi bimetallic nanoparticles for X-ray CT imaging and enhanced antitumor therapy efficiency. Biomaterials. 2021; 264: 13. https://doi.org/10.1016/j.biomaterials.2020.120453.
64 Dong S, Dong Y, Jia T, Liu S, Liu J, Yang D, He F, Gai S, Yang P, Lin J. GSH-Depleted Nanozymes with Hyperthermia-Enhanced Dual Enzyme-Mimic Activities for Tumor Nanocatalytic Therapy. Adv Mater. 2020; 32(42): e2002439. https://doi.org/10.1002/adma.202002439.
65 He Y, Guo S, Wu L, Chen P, Wang L, Liu Y, Ju H. Near-infrared boosted ROS responsive siRNA delivery and cancer therapy with sequentially peeled upconversion nano-onions. Biomaterials. 2019; 225: 119501-119501. https://doi.org/10.1016/j.biomaterials.2019.119501.
66 Deng T, Zhao H, Shi M, Qiu Y, Jiang S, Yang X, Zhao Y, Zhang Y. Photoactivated Trifunctional Platinum Nanobiotics for Precise Synergism of Multiple Antibacterial Modes. Small (Weinheim an der Bergstrasse, Germany). 2019; 15(46): e1902647-e1902647. https://doi.org/10.1002/smll.201902647.
67 Majtnerová P, Roušar T. An overview of apoptosis assays detecting DNA fragmentation. Molecular biology reports. 2018; 45(5): 1469-1478. https://doi.org/10.1007/s11033-018-4258-9.