After the successful validation of the axisymmetric and three-dimensional models to simulate the blow and blow forming process using two axisymmetrical bottles, the capabilities of the 3D model have been evaluated by performing simulations with more complex geometries. This article presents the results of a numerical and experimental study of a non-axisymmetrical glass bottle. In this study, a perfume bottle with a square-based prism geometry and a new set of industrial process conditions have been evaluated. To validate the numerical results, the predicted temperatures in the glass domain have been correlated with experimental infrared measurements of the glass at various stages of the forming process. A comparison of the predicted glass thickness distributions with the section profiles obtained from the manufactured glass bottles is also provided. Finally, transition from the 2Da to 3D model resulted in new difficulties and capabilities that are also discussed.