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Background: Wound-related complications are an inevitable issue faced by spinal surgeons. Negative pressure drainage remains the most commonly used method to prevent postoperative hematoma and related complications. This prospective, randomized, controlled study was conducted to evaluate the efficacy of compression therapy following posterior lumbar interbody fusion, with emphasis on pain, anemia, and inflammation. Methods: Sixty consecutive patients who have undergone posterior lumbar interbody fusion in the age range 43–78 years, with an average age of 59 years, were selected and randomly assigned into two groups. Factors, such as drainage volume, visual analog scale (VAS) pain score for back pain, white blood cell (WBC) count , red blood cell (RBC) count, hemoglobin (Hb) levels, erythrocyte sedimentation rate(ESR), and C-reactive protein (CRP) levels assessed on the 1st, 3rd, and 10th days postoperatively, were compared between the two groups. Results: The average follow-up was 6 months, ranging from 3 to 11 months. Drainage volume, VAS score, and CRP levels on the 10th day after the surgery were found to be significantly lower in the treatment group than in the control group. RBC count and Hb levels on the 3rd and 10th postoperative days were observed to be significantly higher in the treatment group than in the control group ( P <0.05). During discharge, the wounds of the patients of the both groups had healed and neither showed any symptoms of infection, hematoma, or necrosis. Conclusion: Compression therapy relieves pain, alleviates anemia, and the inflammatory response following posterior lumbar interbody fusion.
Keywords
lumbar spine surgery; compression therapy; pain; anemia
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CURRENT STATUS: Published
View the published article at BMC Surgery.
No community comments so far
Submission checks complete
On 07 Nov, 2019
Editorial decision: Accept
On 19 Sep, 2019
Version 2
Posted 01 Oct, 2019
No comments provided
Editorial decision: Minor revision
On 16 Sep, 2019
Editor assigned
On 09 Sep, 2019
Submission checks complete
On 08 Sep, 2019
Editor invited
On 08 Sep, 2019
No comments provided
Editorial decision: Major revision
On 12 Aug, 2019
Review #2 received
Received 11 Aug, 2019
Reviewer #2 agreed
On 28 Jul, 2019
Review #1 received
Received 22 Jul, 2019
Reviewer #1 agreed
On 19 Jul, 2019
Reviewers invited
Invitations sent on 16 Jul, 2019
Editor assigned
On 15 Jul, 2019
Submission checks complete
On 10 Jul, 2019
Editor invited
On 10 Jul, 2019
First submitted
On 07 Jul, 2019
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A new preprint design is coming!
We have improved readability, clarity, accessibility, and opportunities for engagement.
See the published version of this preprint at BMC Surgery.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Surgery.
No community comments so far
Submission checks complete
On 07 Nov, 2019
Editorial decision: Accept
On 19 Sep, 2019
Version 2
Posted 01 Oct, 2019
No comments provided
Editorial decision: Minor revision
On 16 Sep, 2019
Editor assigned
On 09 Sep, 2019
Submission checks complete
On 08 Sep, 2019
Editor invited
On 08 Sep, 2019
No comments provided
Editorial decision: Major revision
On 12 Aug, 2019
Review #2 received
Received 11 Aug, 2019
Reviewer #2 agreed
On 28 Jul, 2019
Review #1 received
Received 22 Jul, 2019
Reviewer #1 agreed
On 19 Jul, 2019
Reviewers invited
Invitations sent on 16 Jul, 2019
Editor assigned
On 15 Jul, 2019
Submission checks complete
On 10 Jul, 2019
Editor invited
On 10 Jul, 2019
First submitted
On 07 Jul, 2019
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at BMC Surgery.
Background: Wound-related complications are an inevitable issue faced by spinal surgeons. Negative pressure drainage remains the most commonly used method to prevent postoperative hematoma and related complications. This prospective, randomized, controlled study was conducted to evaluate the efficacy of compression therapy following posterior lumbar interbody fusion, with emphasis on pain, anemia, and inflammation. Methods: Sixty consecutive patients who have undergone posterior lumbar interbody fusion in the age range 43–78 years, with an average age of 59 years, were selected and randomly assigned into two groups. Factors, such as drainage volume, visual analog scale (VAS) pain score for back pain, white blood cell (WBC) count , red blood cell (RBC) count, hemoglobin (Hb) levels, erythrocyte sedimentation rate(ESR), and C-reactive protein (CRP) levels assessed on the 1st, 3rd, and 10th days postoperatively, were compared between the two groups. Results: The average follow-up was 6 months, ranging from 3 to 11 months. Drainage volume, VAS score, and CRP levels on the 10th day after the surgery were found to be significantly lower in the treatment group than in the control group. RBC count and Hb levels on the 3rd and 10th postoperative days were observed to be significantly higher in the treatment group than in the control group ( P <0.05). During discharge, the wounds of the patients of the both groups had healed and neither showed any symptoms of infection, hematoma, or necrosis. Conclusion: Compression therapy relieves pain, alleviates anemia, and the inflammatory response following posterior lumbar interbody fusion.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7
Figure 8
This is a list of supplementary files associated with this preprint. Click to download.
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