Early Soft Tissue Response to Zirconium Oxide and Titanium Healing Abutments in Vivo: A Dog Study
Background: This study aimed to investigate clinical characteristics and early soft tissues response to zirconium oxide (Zr) and titanium (Ti) abutments in dogs.
Methods: Eight implants-four at each hemi-mandible were inserted after bilateral mandibular third and fourth premolars and first molars extraction. Two Zr and two Ti healing abutments were connected in each unilateral mandible 8 weeks later. The ligation method was used to make peri-implant mucositis model. The twenty-four abutments were divided into four groups, Zr and Ti healing abutments with ligation (ZrL, TiL) and non-ligation (ZrN, TiN) groups. Clinical index, peri-implant crevicular fluid (PICF) and inflammatory cytokines (TNF-α and IL-1β), soft tissue responses were tested. Two-way analysis of variance was used to analyze the data.
Results: The results showed that the clinical index were similar around Zr and Ti healing abutments. PICF in ZrL and TiL groups were significantly higher than those in ZrN and TiN groups. Immunohistochemistry demonstrated inflammatory cells were non-significant differences.
Conclusion: These data indicate soft tissue responses to Zr healing abutments with peri-implant mucositis was comparable to those to Ti healing abutments in vivo, and can provide theoretical foundation for Zr’s clinical application.
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Posted 19 Feb, 2021
Received 12 Feb, 2021
On 11 Feb, 2021
On 09 Feb, 2021
Invitations sent on 09 Feb, 2021
On 09 Feb, 2021
On 09 Feb, 2021
On 19 Jan, 2021
Early Soft Tissue Response to Zirconium Oxide and Titanium Healing Abutments in Vivo: A Dog Study
Posted 19 Feb, 2021
Received 12 Feb, 2021
On 11 Feb, 2021
On 09 Feb, 2021
Invitations sent on 09 Feb, 2021
On 09 Feb, 2021
On 09 Feb, 2021
On 19 Jan, 2021
Background: This study aimed to investigate clinical characteristics and early soft tissues response to zirconium oxide (Zr) and titanium (Ti) abutments in dogs.
Methods: Eight implants-four at each hemi-mandible were inserted after bilateral mandibular third and fourth premolars and first molars extraction. Two Zr and two Ti healing abutments were connected in each unilateral mandible 8 weeks later. The ligation method was used to make peri-implant mucositis model. The twenty-four abutments were divided into four groups, Zr and Ti healing abutments with ligation (ZrL, TiL) and non-ligation (ZrN, TiN) groups. Clinical index, peri-implant crevicular fluid (PICF) and inflammatory cytokines (TNF-α and IL-1β), soft tissue responses were tested. Two-way analysis of variance was used to analyze the data.
Results: The results showed that the clinical index were similar around Zr and Ti healing abutments. PICF in ZrL and TiL groups were significantly higher than those in ZrN and TiN groups. Immunohistochemistry demonstrated inflammatory cells were non-significant differences.
Conclusion: These data indicate soft tissue responses to Zr healing abutments with peri-implant mucositis was comparable to those to Ti healing abutments in vivo, and can provide theoretical foundation for Zr’s clinical application.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5