This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research Article
zhangfa song
Zhejiang University
Corresponding Author
ORCiD: https://orcid.org/0000-0001-6301-1813
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Introduction: Primary colonic lymphoma is a highly rare malignant tumor. There is no standard treatment method for this disease. We report two cases of primary lymphoma of the colon successfully treated with chemotherapy and surgery respectively.
Case Presentation: In the first case, a 61-year-old female presented with the symptoms of abdominal pain for more than one month. The patient was diagnosed with a colonic tumor. However, immunohistochemical examinations confirmed the initial diagnosis of colonic lymphoma. The patient underwent laparoscopic assisted right hemicolectomy and followed by postoperative adjuvant chemotherapy with CHOP regimen (cyclophosphamide, doxorubicin, vincristine, and prednisone), combined with targeted therapy of rituximab. In the second case, a 78-year-old male presented with complaints abdominal distention for more than one year. Diffuse Large B-cell Lymphoma was definitely diagnosed by immunohistochemical examinations. And this patient treated by the systemic chemotherapy with R- CHOP regimen.
Conclusions: Primary colonic lymphoma is a rare type of NHL. The clinical treatment is not standardized unlike many other types of lymphomas. Maybe it is mainly based on the symptoms to determine whether surgery or systemic chemotherapy. Rituximab is effective in some patients which may play an important role in the treatment of unresectable or asymptomatic colonic lymphoma.
Keywords
Case Report, Lymphoma, Colon
Figure 1
Figure 2
Figure 3
Loading...
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 25 Feb, 2021
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Learn more about our company.
This is a preprint. It has not completed peer review.
Research Article
zhangfa song
Zhejiang University
Corresponding Author
ORCiD: https://orcid.org/0000-0001-6301-1813
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 25 Feb, 2021
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Introduction: Primary colonic lymphoma is a highly rare malignant tumor. There is no standard treatment method for this disease. We report two cases of primary lymphoma of the colon successfully treated with chemotherapy and surgery respectively.
Case Presentation: In the first case, a 61-year-old female presented with the symptoms of abdominal pain for more than one month. The patient was diagnosed with a colonic tumor. However, immunohistochemical examinations confirmed the initial diagnosis of colonic lymphoma. The patient underwent laparoscopic assisted right hemicolectomy and followed by postoperative adjuvant chemotherapy with CHOP regimen (cyclophosphamide, doxorubicin, vincristine, and prednisone), combined with targeted therapy of rituximab. In the second case, a 78-year-old male presented with complaints abdominal distention for more than one year. Diffuse Large B-cell Lymphoma was definitely diagnosed by immunohistochemical examinations. And this patient treated by the systemic chemotherapy with R- CHOP regimen.
Conclusions: Primary colonic lymphoma is a rare type of NHL. The clinical treatment is not standardized unlike many other types of lymphomas. Maybe it is mainly based on the symptoms to determine whether surgery or systemic chemotherapy. Rituximab is effective in some patients which may play an important role in the treatment of unresectable or asymptomatic colonic lymphoma.
Figure 1
Figure 2
Figure 3
Loading...