DNA steganography is a technique that utilizes the DNA sequence as the basis for the secure transmission of critical data. This technique consists mainly of encrypting and hiding messages within the high capacity of DNA sequences in order to prevent adversaries from reading and decoding secret messages. However, the biometric system is a technological recognition system that processes information about an individual to distinguish them. Biometrics are used in many applications, including fingerprinting, iris scanning, and face recognition. This research will focus on the development of an effective and secure technique that combines steganography and cryptography. This method aims to protect the image of fingerprints in the communication channel while keeping the information confidential. The hiding process of the proposed system converts fingerprint images into a binary series, which is then added to the DNA sequence after applying the appropriate encryption method. The proposed technique utilizes the Feistel network in the encryption process and uses an insertion technique in the hiding process. It has a low cracking probability, high BPN numbers, and good execution times. During the hiding and decoding processes, the proposed system utilizes four different keys, which are chosen randomly, resulting in a high key space and ahigh key sensitivity. The proposed technique increases the noise by adding some random ambiguity bits at random positions in the fingerprint image. The experimental results show that the proposed system is resistant to several attacks, such as known-plaintext attacks and chosen-plaintext attacks. The proposed technique is limited to hiding only a small image inside the DNA and does not handle video, audio, or a large image size.