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Research article
Jie Peng
Xiangya Hospital Central South University
Corresponding Author
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background
The association of upper gastrointestinal diseases with sex, age and Helicobacter pylori infection in asymptomatic healthy people is unclear.The aim of this study was to retrospectively determine the associations of upper gastrointestinal disease in asymptomatic healthy people with sex, age and H. pylori infection.
Methods
A retrospective study was conducted on 2923 patients from a health examination center in Xiangya Hospital between September 2015 and September 2019. Data on sex, age, H. pylori infection and gastroscopy results were collected.
Results
Among 2923 asymptomatic patients who underwent gastroscopy, 2911 patients (99.59%) had abnormal results. The top three results were chronic gastritis, peptic ulcer, and duodenitis. Inflammation of the gastric mucosa in chronic gastritis was more severe in the H. pylori-positive group. The incidence of peptic ulcer decreased with increasing age and was higher in males, patients aged < 30 years and H. pylori-positive patients.The incidence of polyps was higher in females than in males, and the incidence in individuals aged ≥ 60 years was higher than that in those aged < 60 years.
Conclusion
The incidence of upper gastrointestinal diseases is high in asymptomatic healthy people undergoing a check-up and is associated with sex, age and H. pylori infection.Gastroscopy should be considered part of a routine health check.
Keywords
upper gastrointestinal diseases, gastroscopy, health check, screening
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Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Gastroenterology.
No community comments so far
Submission checks complete
On 20 Nov, 2020
Editorial decision: Accept
On 19 Nov, 2020
No comments provided
Editorial decision: Major revision
On 27 Oct, 2020
Review #2 received
Received 19 Oct, 2020
Reviewer #2 agreed
On 16 Oct, 2020
Review #1 received
Received 29 Jul, 2020
Reviewer #1 agreed
On 25 Jul, 2020
Reviewers invited
Invitations sent on 24 Jul, 2020
Editor assigned
On 19 Jul, 2020
Submission checks complete
On 18 Jul, 2020
Editor invited
On 18 Jul, 2020
Version 1
Posted 07 May, 2020
No comments provided
Editorial decision: Major revision
On 02 Jul, 2020
Review #2 received
Received 22 Jun, 2020
Reviewer #3 agreed
On 14 Jun, 2020
Review #3 received
Received 14 Jun, 2020
Reviewer #2 agreed
On 13 Jun, 2020
Review #1 received
Received 20 May, 2020
Reviewer #1 agreed
On 19 May, 2020
Reviewers invited
Invitations sent on 18 May, 2020
Editor assigned
On 22 Apr, 2020
First submitted
On 21 Apr, 2020
Submission checks complete
On 21 Apr, 2020
Editor invited
On 21 Apr, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Gastroenterology & Hepatology
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A new preprint design is coming!
We have improved readability, clarity, accessibility, and opportunities for engagement.
See the published version of this preprint at BMC Gastroenterology.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Jie Peng
Xiangya Hospital Central South University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Gastroenterology.
No community comments so far
Submission checks complete
On 20 Nov, 2020
Editorial decision: Accept
On 19 Nov, 2020
No comments provided
Editorial decision: Major revision
On 27 Oct, 2020
Review #2 received
Received 19 Oct, 2020
Reviewer #2 agreed
On 16 Oct, 2020
Review #1 received
Received 29 Jul, 2020
Reviewer #1 agreed
On 25 Jul, 2020
Reviewers invited
Invitations sent on 24 Jul, 2020
Editor assigned
On 19 Jul, 2020
Submission checks complete
On 18 Jul, 2020
Editor invited
On 18 Jul, 2020
Version 1
Posted 07 May, 2020
No comments provided
Editorial decision: Major revision
On 02 Jul, 2020
Review #2 received
Received 22 Jun, 2020
Reviewer #3 agreed
On 14 Jun, 2020
Review #3 received
Received 14 Jun, 2020
Reviewer #2 agreed
On 13 Jun, 2020
Review #1 received
Received 20 May, 2020
Reviewer #1 agreed
On 19 May, 2020
Reviewers invited
Invitations sent on 18 May, 2020
Editor assigned
On 22 Apr, 2020
First submitted
On 21 Apr, 2020
Submission checks complete
On 21 Apr, 2020
Editor invited
On 21 Apr, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Gastroenterology & Hepatology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at BMC Gastroenterology.
Background
The association of upper gastrointestinal diseases with sex, age and Helicobacter pylori infection in asymptomatic healthy people is unclear.The aim of this study was to retrospectively determine the associations of upper gastrointestinal disease in asymptomatic healthy people with sex, age and H. pylori infection.
Methods
A retrospective study was conducted on 2923 patients from a health examination center in Xiangya Hospital between September 2015 and September 2019. Data on sex, age, H. pylori infection and gastroscopy results were collected.
Results
Among 2923 asymptomatic patients who underwent gastroscopy, 2911 patients (99.59%) had abnormal results. The top three results were chronic gastritis, peptic ulcer, and duodenitis. Inflammation of the gastric mucosa in chronic gastritis was more severe in the H. pylori-positive group. The incidence of peptic ulcer decreased with increasing age and was higher in males, patients aged < 30 years and H. pylori-positive patients.The incidence of polyps was higher in females than in males, and the incidence in individuals aged ≥ 60 years was higher than that in those aged < 60 years.
Conclusion
The incidence of upper gastrointestinal diseases is high in asymptomatic healthy people undergoing a check-up and is associated with sex, age and H. pylori infection.Gastroscopy should be considered part of a routine health check.
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