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Research Article
Christian Bacci
University of Padua
Corresponding Author
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This work is licensed under a CC BY 4.0 License. Read Full License
OBJECTIVE
Oral lichen planus (OLP) is a chronic inflammatory. Bio-electrical impedance analysis (BIA) is a method for assessing tissue composition. Based on a combination of reactance and resistance data, a phase angle (PA) is calculated. The PA may range in value from 90° to 0°, correlates with body cell mass. There is evidence suggesting that the PA of neoplastic tissue is lower than that of normal tissue. The aim of the present study was to compare the findings of BIA on the oral mucosae of patients with OLP and healthy controls.
MATERIALS AND METHODS
BIA measurements were obtained with a specific device and PA values were calculated, in a sample of 57 consecutive cases OLP and 60 healthy controls. Impedance measurements were taken for the buccal mucosae, tongue, hard palate and upper anterior gums.
RESULTS
The resistance, reactance and PA of the hard plate and gums were generally higher in the OLP group than in the control group, and the differences were statistically significant. The median PA of healthy and reticular lesions was higher than that of erosive lesions.
CONCLUSIONS
These results support the usefulness of BIA for the characterization of healthy oral mucosa and OLP lesions.
Keywords
Cancer, Diagnostic procedure, Oral Lichen Planus, Oral Cancer, Oral Lesions, Oral medicine, Pathology, Stomatognathic Diseases
No competing interests reported.
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CURRENT STATUS: Under Revision
Version 1
Posted 03 Mar, 2021
No community comments so far
Editorial decision: Major revision
On 20 Apr, 2021
Review #3 received
Received 03 Apr, 2021
Review #4 received
Received 03 Apr, 2021
Reviewer #4 agreed
On 08 Mar, 2021
Reviewer #9 agreed
On 08 Mar, 2021
Reviewer #5 agreed
On 08 Mar, 2021
Review #17 received
Received 24 Feb, 2021
Review #16 received
Received 24 Feb, 2021
Review #10 received
Received 24 Feb, 2021
Review #9 received
Received 24 Feb, 2021
Review #18 received
Received 24 Feb, 2021
Review #5 received
Received 24 Feb, 2021
Review #15 received
Received 24 Feb, 2021
Review #11 received
Received 24 Feb, 2021
Review #6 received
Received 24 Feb, 2021
Review #14 received
Received 24 Feb, 2021
Review #7 received
Received 24 Feb, 2021
Review #1 received
Received 24 Feb, 2021
Review #12 received
Received 24 Feb, 2021
Review #13 received
Received 24 Feb, 2021
Review #2 received
Received 24 Feb, 2021
Reviewer #18 agreed
On 24 Feb, 2021
Reviewer #17 agreed
On 24 Feb, 2021
Reviewer #11 agreed
On 24 Feb, 2021
Reviewer #10 agreed
On 24 Feb, 2021
Reviewer #1 agreed
On 24 Feb, 2021
Reviewer #19 agreed
On 24 Feb, 2021
Reviewer #6 agreed
On 24 Feb, 2021
Reviewer #16 agreed
On 24 Feb, 2021
Reviewer #12 agreed
On 24 Feb, 2021
Reviewer #7 agreed
On 24 Feb, 2021
Reviewer #15 agreed
On 24 Feb, 2021
Reviewer #8 agreed
On 24 Feb, 2021
Reviewer #2 agreed
On 24 Feb, 2021
Reviewer #13 agreed
On 24 Feb, 2021
Reviewer #14 agreed
On 24 Feb, 2021
Reviewer #3 agreed
On 24 Feb, 2021
Reviewers invited
Invitations sent on 24 Feb, 2021
Editor assigned
On 23 Feb, 2021
Editor invited
On 22 Feb, 2021
Submission checks complete
On 22 Feb, 2021
First submitted
On 18 Feb, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Biophysics
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This preprint is under consideration at Scientific Reports. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Christian Bacci
University of Padua
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Revision
Version 1
Posted 03 Mar, 2021
No community comments so far
Editorial decision: Major revision
On 20 Apr, 2021
Review #3 received
Received 03 Apr, 2021
Review #4 received
Received 03 Apr, 2021
Reviewer #4 agreed
On 08 Mar, 2021
Reviewer #9 agreed
On 08 Mar, 2021
Reviewer #5 agreed
On 08 Mar, 2021
Review #17 received
Received 24 Feb, 2021
Review #16 received
Received 24 Feb, 2021
Review #10 received
Received 24 Feb, 2021
Review #9 received
Received 24 Feb, 2021
Review #18 received
Received 24 Feb, 2021
Review #5 received
Received 24 Feb, 2021
Review #15 received
Received 24 Feb, 2021
Review #11 received
Received 24 Feb, 2021
Review #6 received
Received 24 Feb, 2021
Review #14 received
Received 24 Feb, 2021
Review #7 received
Received 24 Feb, 2021
Review #1 received
Received 24 Feb, 2021
Review #12 received
Received 24 Feb, 2021
Review #13 received
Received 24 Feb, 2021
Review #2 received
Received 24 Feb, 2021
Reviewer #18 agreed
On 24 Feb, 2021
Reviewer #17 agreed
On 24 Feb, 2021
Reviewer #11 agreed
On 24 Feb, 2021
Reviewer #10 agreed
On 24 Feb, 2021
Reviewer #1 agreed
On 24 Feb, 2021
Reviewer #19 agreed
On 24 Feb, 2021
Reviewer #6 agreed
On 24 Feb, 2021
Reviewer #16 agreed
On 24 Feb, 2021
Reviewer #12 agreed
On 24 Feb, 2021
Reviewer #7 agreed
On 24 Feb, 2021
Reviewer #15 agreed
On 24 Feb, 2021
Reviewer #8 agreed
On 24 Feb, 2021
Reviewer #2 agreed
On 24 Feb, 2021
Reviewer #13 agreed
On 24 Feb, 2021
Reviewer #14 agreed
On 24 Feb, 2021
Reviewer #3 agreed
On 24 Feb, 2021
Reviewers invited
Invitations sent on 24 Feb, 2021
Editor assigned
On 23 Feb, 2021
Editor invited
On 22 Feb, 2021
Submission checks complete
On 22 Feb, 2021
First submitted
On 18 Feb, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Biophysics
License:
This work is licensed under a CC BY 4.0 License. Read Full License
OBJECTIVE
Oral lichen planus (OLP) is a chronic inflammatory. Bio-electrical impedance analysis (BIA) is a method for assessing tissue composition. Based on a combination of reactance and resistance data, a phase angle (PA) is calculated. The PA may range in value from 90° to 0°, correlates with body cell mass. There is evidence suggesting that the PA of neoplastic tissue is lower than that of normal tissue. The aim of the present study was to compare the findings of BIA on the oral mucosae of patients with OLP and healthy controls.
MATERIALS AND METHODS
BIA measurements were obtained with a specific device and PA values were calculated, in a sample of 57 consecutive cases OLP and 60 healthy controls. Impedance measurements were taken for the buccal mucosae, tongue, hard palate and upper anterior gums.
RESULTS
The resistance, reactance and PA of the hard plate and gums were generally higher in the OLP group than in the control group, and the differences were statistically significant. The median PA of healthy and reticular lesions was higher than that of erosive lesions.
CONCLUSIONS
These results support the usefulness of BIA for the characterization of healthy oral mucosa and OLP lesions.
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