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Research Article
Wei He
First Affiliated Hospital of Zhengzhou University
Corresponding Author
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Mandibular defects directly affect a patient’ facial features, masticatory and articulation. This study has analyzed 41 patients with mandibular ameloblastoma who underwent a partial mandibulectomy and reconstruction by folding the free fibular flap. In the preoperative and postoperative (6 months and 24 months after surgery), the QOL of these patients was assessed by using the University of Washington Quality of Life Questionnaire (UW-QOL) and the medical outcome study short form-36 (SF-36) questionnaires. The sf-36 survey showed that body pain, general health, and health changes decreased significantly at 6 months after surgery, but the mean score at 24 months after surgery all exceeded that shown before surgery. The UW-QOL survey showed that chewing, speech and taste had significantly changed in the 6 months after the surgery, and the difference was statistically significant 24 months after the surgery. The total score of the patients almost recovered to the preoperative level at 24 months after the surgery. The folded free fibular flap is an ideal selection for the reconstruction of oral defects after cancer resection. In using this flap, the basic social need of patients after surgery can be satisfied. The folded free fibular flap can improve the patients’ QOL.
Keywords
Mandibular defects, free fibular flap, mandibular ameloblastoma, oral defects, Quality of Life
Figure 1
Figure 2
No competing interests reported.
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CURRENT STATUS: Under Review
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Posted 10 Mar, 2021
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On 27 Apr, 2021
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Received 16 Apr, 2021
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This preprint is under consideration at Scientific Reports. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Wei He
First Affiliated Hospital of Zhengzhou University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 10 Mar, 2021
No community comments so far
Editorial decision: Major revision
On 27 Apr, 2021
Reviews received
Received 16 Apr, 2021
Reviewers agreed
On 16 Apr, 2021
Reviewers invited
Invitations sent on 16 Apr, 2021
Editor assigned
On 16 Apr, 2021
Editor invited
On 09 Mar, 2021
Submission checks complete
On 09 Mar, 2021
First submitted
On 19 Feb, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Mandibular defects directly affect a patient’ facial features, masticatory and articulation. This study has analyzed 41 patients with mandibular ameloblastoma who underwent a partial mandibulectomy and reconstruction by folding the free fibular flap. In the preoperative and postoperative (6 months and 24 months after surgery), the QOL of these patients was assessed by using the University of Washington Quality of Life Questionnaire (UW-QOL) and the medical outcome study short form-36 (SF-36) questionnaires. The sf-36 survey showed that body pain, general health, and health changes decreased significantly at 6 months after surgery, but the mean score at 24 months after surgery all exceeded that shown before surgery. The UW-QOL survey showed that chewing, speech and taste had significantly changed in the 6 months after the surgery, and the difference was statistically significant 24 months after the surgery. The total score of the patients almost recovered to the preoperative level at 24 months after the surgery. The folded free fibular flap is an ideal selection for the reconstruction of oral defects after cancer resection. In using this flap, the basic social need of patients after surgery can be satisfied. The folded free fibular flap can improve the patients’ QOL.
Figure 1
Figure 2
No competing interests reported.
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