In today’s scenario, mobile communication is facing a healthy competition due to different networks, interfaces, channels, and many more available in wireless heterogeneous environment. The problem arises when customers/users get the availability of many interfaces at the same time. At that time users need an intelligent or smart mechanism to connect them to the best services according to their requirements/preferences. Interface management manages available interfaces and connects the user with the best. In this paper, Interface management with Artificial Neural Network (ANN) allows the smart use of different radio accesses/interfaces. The selection is made with different parameters of different networks. This paper proposed a backpropagation neural network that is used for the switching in between different networks-3G, WLAN, 4G and 5G. The different parameters of a network are used as the selection parameters with assigning proper weights. Weights are initialized with fuzzy AHP and optimized with Back Propagation Neural Network (BPNN). The target value and the actual value is compared and their difference used as the adjusting value for the weights to get the optimum value. The backpropagation is used to train the network. The comparison among the projected algorithm and the existing algorithm shows the valuablity of the new method and the best connectivity of the network.