This preprint is under consideration at Journal of Ophthalmic Inflammation and Infection. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
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Brief report
Sarah Madison Duff
University of Florida
Corresponding Author
ORCiD: https://orcid.org/0000-0002-2851-093X
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Purpose
To report panuveitis due to Toxocara, with positive Toxoplasma serology.
Observation
A nine-year-old boy presented with a panuveitis, intermittent headaches, and a visual acuity of 20/400 in his left eye. Slit lamp examination showed anterior chamber cells and flare without keratic precipitates (KPs), vitreous cells and veils, and optic disc edema with a blurred fundus view. Initial lab values were positive for toxoplasmosis. Topical cycloplegic and steroid eye drops, in addition to trimethoprim/sulfamethoxazole (TMP/SMX) treatment, was initiated. Four days later, oral corticosteroids were started. As inflammation cleared, the fundus examination showed an inferior tractional detachment, leading to an ultimate diagnosis of ocular Toxocariasis.
Conclusion and Importance
High false positives on Toxoplasma serology and diffuse vitritis from toxocariasis limiting retinal visualization may confuse the initial diagnosis.
Keywords
Toxocara canis, Toxocariasis, Toxoplasmosis, Panuveitis, Neuroretinitis, Tractional Retinal Detachment, Granuloma
Figure 1
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Peer Review Timeline
CURRENT STATUS: Under Review
Version (no preprint)
Posted 30 Oct, 2021
Review #1 received
Received 30 Oct, 2021
Editorial decision: Minor Revision
On 30 Oct, 2021
Reviews received
Received 19 Oct, 2021
Reviewers invited
Invitations sent on 19 Oct, 2021
Reviewer #1 agreed
On 18 Oct, 2021
First submitted
On 05 Oct, 2021
Editor assigned
On 04 Oct, 2021
Submission checks complete
On 04 Oct, 2021
Editor invited
On 04 Oct, 2021
This version was not preprinted
Version (no preprint)
Posted 12 Jul, 2021
Editorial decision: Minor Revision
On 12 Jul, 2021
Review #2 received
Received 08 Jul, 2021
Reviewer #2 agreed
On 23 Jun, 2021
Review #1 received
Received 04 May, 2021
Reviews received
Received 03 May, 2021
Reviewers invited
Invitations sent on 03 May, 2021
Reviewer #1 agreed
On 03 May, 2021
Editor assigned
On 29 Apr, 2021
Submission checks complete
On 29 Apr, 2021
Editor invited
On 29 Apr, 2021
First submitted
On 28 Apr, 2021
This version was not preprinted
Version (no preprint)
Posted 04 May, 2021
Review #1 received
Received 04 May, 2021
Reviewers invited
Invitations sent on 03 May, 2021
Reviewer #1 agreed
On 03 May, 2021
Editor assigned
On 29 Apr, 2021
Submission checks complete
On 29 Apr, 2021
Editor invited
On 29 Apr, 2021
This version was not preprinted
Version 1
Posted 10 Mar, 2021
No community comments so far
Editorial decision: Major Revision
On 22 Mar, 2021
Review #2 received
Received 21 Mar, 2021
Review #1 received
Received 19 Mar, 2021
Reviewer #2 agreed
On 11 Mar, 2021
Reviews received
Received 06 Mar, 2021
Reviewer #1 agreed
On 06 Mar, 2021
Reviewers invited
Invitations sent on 05 Mar, 2021
Editor assigned
On 28 Feb, 2021
Submission checks complete
On 28 Feb, 2021
Editor invited
On 28 Feb, 2021
First submitted
On 21 Feb, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Neurobiology of Disease
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This preprint is under consideration at Journal of Ophthalmic Inflammation and Infection. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Brief report
Sarah Madison Duff
University of Florida
Corresponding Author
ORCiD: https://orcid.org/0000-0002-2851-093X
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version (no preprint)
Posted 30 Oct, 2021
Review #1 received
Received 30 Oct, 2021
Editorial decision: Minor Revision
On 30 Oct, 2021
Reviews received
Received 19 Oct, 2021
Reviewers invited
Invitations sent on 19 Oct, 2021
Reviewer #1 agreed
On 18 Oct, 2021
First submitted
On 05 Oct, 2021
Editor assigned
On 04 Oct, 2021
Submission checks complete
On 04 Oct, 2021
Editor invited
On 04 Oct, 2021
This version was not preprinted
Version (no preprint)
Posted 12 Jul, 2021
Editorial decision: Minor Revision
On 12 Jul, 2021
Review #2 received
Received 08 Jul, 2021
Reviewer #2 agreed
On 23 Jun, 2021
Review #1 received
Received 04 May, 2021
Reviews received
Received 03 May, 2021
Reviewers invited
Invitations sent on 03 May, 2021
Reviewer #1 agreed
On 03 May, 2021
Editor assigned
On 29 Apr, 2021
Submission checks complete
On 29 Apr, 2021
Editor invited
On 29 Apr, 2021
First submitted
On 28 Apr, 2021
This version was not preprinted
Version (no preprint)
Posted 04 May, 2021
Review #1 received
Received 04 May, 2021
Reviewers invited
Invitations sent on 03 May, 2021
Reviewer #1 agreed
On 03 May, 2021
Editor assigned
On 29 Apr, 2021
Submission checks complete
On 29 Apr, 2021
Editor invited
On 29 Apr, 2021
This version was not preprinted
Version 1
Posted 10 Mar, 2021
No community comments so far
Editorial decision: Major Revision
On 22 Mar, 2021
Review #2 received
Received 21 Mar, 2021
Review #1 received
Received 19 Mar, 2021
Reviewer #2 agreed
On 11 Mar, 2021
Reviews received
Received 06 Mar, 2021
Reviewer #1 agreed
On 06 Mar, 2021
Reviewers invited
Invitations sent on 05 Mar, 2021
Editor assigned
On 28 Feb, 2021
Submission checks complete
On 28 Feb, 2021
Editor invited
On 28 Feb, 2021
First submitted
On 21 Feb, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Neurobiology of Disease
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Purpose
To report panuveitis due to Toxocara, with positive Toxoplasma serology.
Observation
A nine-year-old boy presented with a panuveitis, intermittent headaches, and a visual acuity of 20/400 in his left eye. Slit lamp examination showed anterior chamber cells and flare without keratic precipitates (KPs), vitreous cells and veils, and optic disc edema with a blurred fundus view. Initial lab values were positive for toxoplasmosis. Topical cycloplegic and steroid eye drops, in addition to trimethoprim/sulfamethoxazole (TMP/SMX) treatment, was initiated. Four days later, oral corticosteroids were started. As inflammation cleared, the fundus examination showed an inferior tractional detachment, leading to an ultimate diagnosis of ocular Toxocariasis.
Conclusion and Importance
High false positives on Toxoplasma serology and diffuse vitritis from toxocariasis limiting retinal visualization may confuse the initial diagnosis.
Figure 1
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