This preprint is under consideration at BMC Pregnancy and Childbirth. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
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Research Article
Hailu Hailemariam
Hawassa University
Corresponding Author
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Background: Preterm birth is a birth that occurs before 37 weeks of gestational age since the first day of a woman’s last menstrual period. In Ethiopia, 10% of babies born preterm each year. Preterm birth is the major cause of neonatal deaths next to pneumonia and it is a substantial cause of long-term problems in survivors. The objective of the study was to identify key determinants of preterm birth in Kembata Tembaro, Southern Ethiopia, 2019.
Method: Institutional unmatched case-control study design was employed on 310 mothers who gave full-term births as control and 104 mothers with preterm births as cases from October 1, 2018, to February 1, 2019. The study participants were selected using a consecutive sampling method. SPSS version 20 was used to analyze the data.
Result: A total of 104 (25.1%) cases and 310 (74.9%) controls were included in the analysis with a 100% response rate. Factors such as rural resident, AOR =2.7; 95% CI [1.3, 5.6], uneducated, AOR= 2.6; 95% CI [1.3, 5.2], ANC visits <4 times, AOR =5.5; 95% CI [2.1, 14.3], substance abuse, AOR =3.5; 95% CI [1.1, 10.5], MUAC <23cm, AOR= 7.2; 95%CI [3.3, 15.7], pregnancy-induced hypertension, AOR =8.9; 95%CI[1.2, 69], history of abortion, AOR =11.1; 95%CI[1.2, 105], FCS <=21.4, AOR =20.7; 95%CI[10, 42.2], and low birth weight, AOR= 20.2; 95%CI[10.5, 39] were identified as significant determinants of preterm birth.
Conclusion: Education level, rural residence, Poor antenatal care visits, substance abuse, pregnancy-induced hypertension, and history of abortion are the key factors associated with pre-term birth. Community awareness and mobilization should be strengthened through extension programs. Emphasis should be given to strengthening efforts on the availability of basic health services and promoting education on nutrition during pregnancy, especially in rural areas. Further study is recommended regarding the effect of maternal nutrition on preterm birth using a prospective study design.
Keywords
Preterm, determinants, neonate, Kembata Tembaro, Southern, Ethiopia
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On 30 Mar, 2021
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On 30 Mar, 2021
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This preprint is under consideration at BMC Pregnancy and Childbirth. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Hailu Hailemariam
Hawassa University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 04 Mar, 2021
No community comments so far
Reviewer #4 agreed
On 30 Mar, 2021
Reviewer #5 agreed
On 30 Mar, 2021
Reviewer #1 agreed
On 30 Mar, 2021
Reviewer #3 agreed
On 30 Mar, 2021
Reviewer #2 agreed
On 30 Mar, 2021
Reviewers invited
Invitations sent on 29 Mar, 2021
Editor assigned
On 03 Mar, 2021
Editor invited
On 02 Mar, 2021
Submission checks complete
On 02 Mar, 2021
First submitted
On 22 Feb, 2021
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Preterm birth is a birth that occurs before 37 weeks of gestational age since the first day of a woman’s last menstrual period. In Ethiopia, 10% of babies born preterm each year. Preterm birth is the major cause of neonatal deaths next to pneumonia and it is a substantial cause of long-term problems in survivors. The objective of the study was to identify key determinants of preterm birth in Kembata Tembaro, Southern Ethiopia, 2019.
Method: Institutional unmatched case-control study design was employed on 310 mothers who gave full-term births as control and 104 mothers with preterm births as cases from October 1, 2018, to February 1, 2019. The study participants were selected using a consecutive sampling method. SPSS version 20 was used to analyze the data.
Result: A total of 104 (25.1%) cases and 310 (74.9%) controls were included in the analysis with a 100% response rate. Factors such as rural resident, AOR =2.7; 95% CI [1.3, 5.6], uneducated, AOR= 2.6; 95% CI [1.3, 5.2], ANC visits <4 times, AOR =5.5; 95% CI [2.1, 14.3], substance abuse, AOR =3.5; 95% CI [1.1, 10.5], MUAC <23cm, AOR= 7.2; 95%CI [3.3, 15.7], pregnancy-induced hypertension, AOR =8.9; 95%CI[1.2, 69], history of abortion, AOR =11.1; 95%CI[1.2, 105], FCS <=21.4, AOR =20.7; 95%CI[10, 42.2], and low birth weight, AOR= 20.2; 95%CI[10.5, 39] were identified as significant determinants of preterm birth.
Conclusion: Education level, rural residence, Poor antenatal care visits, substance abuse, pregnancy-induced hypertension, and history of abortion are the key factors associated with pre-term birth. Community awareness and mobilization should be strengthened through extension programs. Emphasis should be given to strengthening efforts on the availability of basic health services and promoting education on nutrition during pregnancy, especially in rural areas. Further study is recommended regarding the effect of maternal nutrition on preterm birth using a prospective study design.
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