Background: A dynamic change in weight over time has been known as an important factor that impacts mortality risk. However, it is currently unknown how the dynamic change of body mass index (BMI) contributes to the cause-specific mortality risk.
Methods: In this cohort study, we obtained data from a large prospective cohort study in Taiwan between 1998 and 2019, which was linked to National Death Registry for death information. The database accumulated 290,279 participants who were born before 1977. We excluded those who were less than 40 years old at 1998 (n=51,731), less than two waves follow-up (n=145,270), and who had ever been diagnosed at baseline with any of the following self-reported conditions: cancer, stroke (n=3392) with a final 89,886 participants.
Results: This study shows that different trajectories are associated with mortality suggests that the mortality risk differs in each trajectory group and in each age and gender stratification. It appears that obesity is a protective factor in cancer-related mortality in females but not in males in the group of old age; low-normal weight is a risk factor in respiratory-related mortality in all participants.
Conclusions: Our findings can be used to define the appropriate BMI in each age and gender groups and thereby earlier health interventions can be taken to avoid mortality.
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Posted 11 Mar, 2021
On 14 Mar, 2021
Received 14 Mar, 2021
Invitations sent on 13 Mar, 2021
On 27 Feb, 2021
On 27 Feb, 2021
On 24 Feb, 2021
On 23 Feb, 2021
Posted 11 Mar, 2021
On 14 Mar, 2021
Received 14 Mar, 2021
Invitations sent on 13 Mar, 2021
On 27 Feb, 2021
On 27 Feb, 2021
On 24 Feb, 2021
On 23 Feb, 2021
Background: A dynamic change in weight over time has been known as an important factor that impacts mortality risk. However, it is currently unknown how the dynamic change of body mass index (BMI) contributes to the cause-specific mortality risk.
Methods: In this cohort study, we obtained data from a large prospective cohort study in Taiwan between 1998 and 2019, which was linked to National Death Registry for death information. The database accumulated 290,279 participants who were born before 1977. We excluded those who were less than 40 years old at 1998 (n=51,731), less than two waves follow-up (n=145,270), and who had ever been diagnosed at baseline with any of the following self-reported conditions: cancer, stroke (n=3392) with a final 89,886 participants.
Results: This study shows that different trajectories are associated with mortality suggests that the mortality risk differs in each trajectory group and in each age and gender stratification. It appears that obesity is a protective factor in cancer-related mortality in females but not in males in the group of old age; low-normal weight is a risk factor in respiratory-related mortality in all participants.
Conclusions: Our findings can be used to define the appropriate BMI in each age and gender groups and thereby earlier health interventions can be taken to avoid mortality.
Figure 1
Figure 2
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