See the published version of this preprint at European Journal of Medical Research.
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Qiu-Hong Li
First Affiliated Hospital of Dalian Medical University
Corresponding Author
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Background: This current study is aimed to analyze the prognostic factors affecting the short-term efficacy of non-surgical treatment of patients in periodontitis from stage Ⅱ to stage Ⅳ by the multilevel modelling analysis.
Materials and Methods: A total of 58 patients with chronic periodontitis were included in this study. Patients were clinically explored before and 3 months after the treatment and the difference in probing depth was determined [ Reduction of probing depth (Δ PD) = baseline PD - finial probing depth (FPD)]. Three different levels were analyzed: patients, teeth and sites to construct a multi-layer linear model.
Results: Probing depth (PD) improved significantly compared with that before treatment (p < 0.05), in which FPD was (3.90±1.39) mm, and the ΔPD was (1.79±0.97) mm. Compared with the mesial sites and distal sites of the multi-rooted teeth, the number of PD ≥ 5mm or PD < 5mm after the treatment was significantly different (P < 0.05), and the proportion of PD < 5mm was higher in mesial sites. The null model showed that Δ PD varied greatly between groups at various levels (P <0.001), with prediction variable of site level, tooth level, and patient level accounted for 66%, 18%, and 16% of the overall difference, respectively. The complete model showed that the Δ PD of smokers was significantly lower than that of non-smokers (P < 0.001). The Δ PD of the mesial and distal sites was larger than that of the buccolingual central site (P < 0.001). The Δ PD of single-rooted teeth was larger than that of multi-rooted teeth (P < 0.001). The baseline PD, tooth mobility (TM), bleeding index (BI), clinical attachment loss (CAL) were significantly negatively correlated with Δ PD (P < 0.001).
Conclusions: Patients with periodontitis from stage Ⅱ to stage Ⅳ, who are non-smoking, have good compliance, good awareness of oral health, and low percentage sites with PD ≥ 5mm at baseline, single rooted teeth with hypomobility, less clinical attachment loss and lower bleeding index and sites of mesial or distal can obtain an ideal short-term efficacy of non-surgical treatment.
Keywords
periodontitis, non-surgical treatment, multi-level linear model, prognosis
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Peer Review Timeline
CURRENT STATUS: Published
View the published article at European Journal of Medical Research.
Version 2
Posted 04 Jan, 2021
No community comments so far
Editorial decision: Accept
On 16 May, 2021
Review #1 received
Received 31 Mar, 2021
Reviewers invited
Invitations sent on 15 Mar, 2021
Reviewer #1 agreed
On 15 Mar, 2021
Editor assigned
On 15 Dec, 2020
Submission checks complete
On 15 Dec, 2020
Editor invited
On 15 Dec, 2020
First submitted
On 14 Dec, 2020
No comments provided
Editorial decision: Major revision
On 23 Nov, 2020
Review #1 received
Received 30 Sep, 2020
Reviewer #1 agreed
On 16 Sep, 2020
Reviewers invited
Invitations sent on 13 May, 2020
First submitted
On 07 May, 2020
Editor assigned
On 07 May, 2020
Submission checks complete
On 06 May, 2020
Editor invited
On 06 May, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Dentistry
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A new preprint design is coming!
We have improved readability, clarity, accessibility, and opportunities for engagement.
See the published version of this preprint at European Journal of Medical Research.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research
Qiu-Hong Li
First Affiliated Hospital of Dalian Medical University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at European Journal of Medical Research.
Version 2
Posted 04 Jan, 2021
No community comments so far
Editorial decision: Accept
On 16 May, 2021
Review #1 received
Received 31 Mar, 2021
Reviewers invited
Invitations sent on 15 Mar, 2021
Reviewer #1 agreed
On 15 Mar, 2021
Editor assigned
On 15 Dec, 2020
Submission checks complete
On 15 Dec, 2020
Editor invited
On 15 Dec, 2020
First submitted
On 14 Dec, 2020
No comments provided
Editorial decision: Major revision
On 23 Nov, 2020
Review #1 received
Received 30 Sep, 2020
Reviewer #1 agreed
On 16 Sep, 2020
Reviewers invited
Invitations sent on 13 May, 2020
First submitted
On 07 May, 2020
Editor assigned
On 07 May, 2020
Submission checks complete
On 06 May, 2020
Editor invited
On 06 May, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Dentistry
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at European Journal of Medical Research.
Background: This current study is aimed to analyze the prognostic factors affecting the short-term efficacy of non-surgical treatment of patients in periodontitis from stage Ⅱ to stage Ⅳ by the multilevel modelling analysis.
Materials and Methods: A total of 58 patients with chronic periodontitis were included in this study. Patients were clinically explored before and 3 months after the treatment and the difference in probing depth was determined [ Reduction of probing depth (Δ PD) = baseline PD - finial probing depth (FPD)]. Three different levels were analyzed: patients, teeth and sites to construct a multi-layer linear model.
Results: Probing depth (PD) improved significantly compared with that before treatment (p < 0.05), in which FPD was (3.90±1.39) mm, and the ΔPD was (1.79±0.97) mm. Compared with the mesial sites and distal sites of the multi-rooted teeth, the number of PD ≥ 5mm or PD < 5mm after the treatment was significantly different (P < 0.05), and the proportion of PD < 5mm was higher in mesial sites. The null model showed that Δ PD varied greatly between groups at various levels (P <0.001), with prediction variable of site level, tooth level, and patient level accounted for 66%, 18%, and 16% of the overall difference, respectively. The complete model showed that the Δ PD of smokers was significantly lower than that of non-smokers (P < 0.001). The Δ PD of the mesial and distal sites was larger than that of the buccolingual central site (P < 0.001). The Δ PD of single-rooted teeth was larger than that of multi-rooted teeth (P < 0.001). The baseline PD, tooth mobility (TM), bleeding index (BI), clinical attachment loss (CAL) were significantly negatively correlated with Δ PD (P < 0.001).
Conclusions: Patients with periodontitis from stage Ⅱ to stage Ⅳ, who are non-smoking, have good compliance, good awareness of oral health, and low percentage sites with PD ≥ 5mm at baseline, single rooted teeth with hypomobility, less clinical attachment loss and lower bleeding index and sites of mesial or distal can obtain an ideal short-term efficacy of non-surgical treatment.
Figure 1
Figure 2
This is a list of supplementary files associated with this preprint. Click to download.
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