1 Quaresma, M., Coleman, M. P. & Rachet, B. 40-year trends in an index of survival for all cancers combined and survival adjusted for age and sex for each cancer in England and Wales, 1971-2011: a population-based study. Lancet385, 1206-1218, doi:10.1016/s0140-6736(14)61396-9 (2015).
2 Bates, S. E. Pancreatic Cancer: Challenge and Inspiration. Clinical cancer research : an official journal of the American Association for Cancer Research23, 1628, doi:10.1158/1078-0432.ccr-16-2069 (2017).
3 Strobel, O., Neoptolemos, J., Jäger, D. & Büchler, M. W. Optimizing the outcomes of pancreatic cancer surgery. Nature reviews. Clinical oncology16, 11-26, doi:10.1038/s41571-018-0112-1 (2019).
4 Fu, Y., Dominissini, D., Rechavi, G. & He, C. Gene expression regulation mediated through reversible m⁶A RNA methylation. Nature reviews. Genetics15, 293-306, doi:10.1038/nrg3724 (2014).
5 Pan, Y., Ma, P., Liu, Y., Li, W. & Shu, Y. Multiple functions of m(6)A RNA methylation in cancer. Journal of hematology & oncology11, 48, doi:10.1186/s13045-018-0590-8 (2018).
6 Zaccara, S., Ries, R. J. & Jaffrey, S. R. Reading, writing and erasing mRNA methylation. Nature reviews. Molecular cell biology20, 608-624, doi:10.1038/s41580-019-0168-5 (2019).
7 Guo, X. et al. RNA demethylase ALKBH5 prevents pancreatic cancer progression by posttranscriptional activation of PER1 in an m6A-YTHDF2-dependent manner. Molecular cancer19, 91, doi:10.1186/s12943-020-01158-w (2020).
8 Hu, X. et al. IGF2BP2 regulates DANCR by serving as an N6-methyladenosine reader. Cell death and differentiation27, 1782-1794, doi:10.1038/s41418-019-0461-z (2020).
9 Tang, B. et al. m(6)A demethylase ALKBH5 inhibits pancreatic cancer tumorigenesis by decreasing WIF-1 RNA methylation and mediating Wnt signaling. Molecular cancer19, 3, doi:10.1186/s12943-019-1128-6 (2020).
10 Tian, J. et al. N(6)-methyladenosine mRNA methylation of PIK3CB regulates AKT signalling to promote PTEN-deficient pancreatic cancer progression. Gut69, 2180-2192, doi:10.1136/gutjnl-2019-320179 (2020).
11 Wang, M. et al. Upregulation of METTL14 mediates the elevation of PERP mRNA N(6) adenosine methylation promoting the growth and metastasis of pancreatic cancer. Molecular cancer19, 130, doi:10.1186/s12943-020-01249-8 (2020).
12 Zhang, J. et al. Excessive miR-25-3p maturation via N(6)-methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression. Nature communications10, 1858, doi:10.1038/s41467-019-09712-x (2019).
13 Schmitt, A. M. & Chang, H. Y. Long Noncoding RNAs in Cancer Pathways. Cancer cell29, 452-463, doi:10.1016/j.ccell.2016.03.010 (2016).
14 Li, Z. H. et al. The long non-coding RNA HOTTIP promotes progression and gemcitabine resistance by regulating HOXA13 in pancreatic cancer. Journal Of Translational Medicine13, doi:10.1186/s12967-015-0442-z (2015).
15 Ma, C. C. et al. H19 promotes pancreatic cancer metastasis by derepressing let-7's suppression on its target HMGA2-mediated EMT. Tumor Biology35, 9163-9169, doi:10.1007/s13277-014-2185-5 (2014).
16 Pang, E. J., Yang, R., Fu, X. B. & Liu, Y. F. Overexpression of long non-coding RNA MALAT1 is correlated with clinical progression and unfavorable prognosis in pancreatic cancer. Tumor Biology36, 2403-2407, doi:10.1007/s13277-014-2850-8 (2015).
17 Zhou, Y. et al. Metascape provides a biologist-oriented resource for the analysis of systems-level datasets. Nature communications10, 1523, doi:10.1038/s41467-019-09234-6 (2019).
18 Yoshihara, K. et al. Inferring tumour purity and stromal and immune cell admixture from expression data. Nature communications4, 2612, doi:10.1038/ncomms3612 (2013).
19 Gentles, A. J. et al. The prognostic landscape of genes and infiltrating immune cells across human cancers. Nature medicine21, 938-945, doi:10.1038/nm.3909 (2015).
20 Li, Y. et al. LncMAP: Pan-cancer atlas of long noncoding RNA-mediated transcriptional network perturbations. Nucleic acids research46, 1113-1123, doi:10.1093/nar/gkx1311 (2018).
21 Shannon, P. et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome research13, 2498-2504, doi:10.1101/gr.1239303 (2003).
22 Ilango, S., Paital, B., Jayachandran, P., Padma, P. R. & Nirmaladevi, R. Epigenetic alterations in cancer. Frontiers in bioscience (Landmark edition)25, 1058-1109 (2020).
23 Ni, W. et al. Long noncoding RNA GAS5 inhibits progression of colorectal cancer by interacting with and triggering YAP phosphorylation and degradation and is negatively regulated by the m(6)A reader YTHDF3. Molecular cancer18, 143, doi:10.1186/s12943-019-1079-y (2019).
24 Hazra, D., Chapat, C. & Graille, M. m⁶A mRNA Destiny: Chained to the rhYTHm by the YTH-Containing Proteins. Genes10, doi:10.3390/genes10010049 (2019).
25 He, Y. et al. ALKBH5 Inhibits Pancreatic Cancer Motility by Decreasing Long Non-Coding RNA KCNK15-AS1 Methylation. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology48, 838-846, doi:10.1159/000491915 (2018).
26 Wu, K. et al. Long non-coding RNA MIR4435-1HG promotes cancer growth in clear cell renal cell carcinoma. Cancer biomarkers : section A of Disease markers29, 39-50, doi:10.3233/cbm-201451 (2020).
27 Yu, W. D., Wang, H., He, Q. F., Xu, Y. & Wang, X. C. Long noncoding RNAs in cancer-immunity cycle. Journal of cellular physiology233, 6518-6523, doi:10.1002/jcp.26568 (2018).
28 Jiang, R. et al. The long noncoding RNA lnc-EGFR stimulates T-regulatory cells differentiation thus promoting hepatocellular carcinoma immune evasion. Nature communications8, 15129, doi:10.1038/ncomms15129 (2017).
29 Zhou, W. Y. et al. Long noncoding RNA LINC00473 drives the progression of pancreatic cancer via upregulating programmed death-ligand 1 by sponging microRNA-195-5p. Journal of cellular physiology234, 23176-23189, doi:10.1002/jcp.28884 (2019).