This preprint is under consideration at International Ophthalmology. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
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Research Article
Dipankar Das
Sri Sankaradeva Nethralaya
Corresponding Author
ORCiD: https://orcid.org/0000-0001-5699-3767
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Purpose: To study the clinical profile on non-arteritic ischemic optic neuropathy (NAION) and review of literature at a tertiary institute of northeast India
Methods: Retrospective analysis the records of all 61 patients diagnosed with NAION between September 2016 and December 2018. All the patients were dealt on an outpatient basis. Standard clinical details and findings were consistent with NAION. Visual field with 30-2 was done and in selected cases. All patient with optic neuritis, arteritic optic neuropathy, trauma, underlying malignancies were excluded from the study
Results: Of the 61 patients in the study, 41 (67.2%) were males and 20 (32.8%) were females. The mean age was 56 years. Duration of reporting to the institute less than 14 days was seen in 7cases (11.47%). Of the 61 patients, the right eye was affected in 30 (49.1%), left eye in 25 (41%) and both eyes in six (9.8%) patients. In this study we found that 18 (29.5%) patients had diabetes, 24 (39.3%) had hypertension, hypercholesterolemia in 13 (21.3%) cases and 18 (29.5%) cases gave a history of smoking. Two (3.27%) cases gave a history of using sildenafil. Associated macular oedema was seen in seven patients (11.47%)
Conclusion: Early reporting (< 2weeks) of NAAION cases in a tertiary institute of northeast India was found to be low in the study. Macular edema in isolated cases was important where additional treatment was required. Lifestyle modifications of avoiding smoking and tobacco can be suggested in substance abuse cases.
Keywords
Diabetes, Hypertension, Ischemia, Non-Arteritic Anterior Ischemic Optic Neuropathy, Smoking
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This preprint is under consideration at International Ophthalmology. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Dipankar Das
Sri Sankaradeva Nethralaya
Corresponding Author
ORCiD: https://orcid.org/0000-0001-5699-3767
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 11 Mar, 2021
No community comments so far
Review #? received
Received 05 Mar, 2021
Reviewers invited
Invitations sent on 05 Mar, 2021
Editor assigned
On 24 Feb, 2021
First submitted
On 24 Feb, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Ophthalmology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Purpose: To study the clinical profile on non-arteritic ischemic optic neuropathy (NAION) and review of literature at a tertiary institute of northeast India
Methods: Retrospective analysis the records of all 61 patients diagnosed with NAION between September 2016 and December 2018. All the patients were dealt on an outpatient basis. Standard clinical details and findings were consistent with NAION. Visual field with 30-2 was done and in selected cases. All patient with optic neuritis, arteritic optic neuropathy, trauma, underlying malignancies were excluded from the study
Results: Of the 61 patients in the study, 41 (67.2%) were males and 20 (32.8%) were females. The mean age was 56 years. Duration of reporting to the institute less than 14 days was seen in 7cases (11.47%). Of the 61 patients, the right eye was affected in 30 (49.1%), left eye in 25 (41%) and both eyes in six (9.8%) patients. In this study we found that 18 (29.5%) patients had diabetes, 24 (39.3%) had hypertension, hypercholesterolemia in 13 (21.3%) cases and 18 (29.5%) cases gave a history of smoking. Two (3.27%) cases gave a history of using sildenafil. Associated macular oedema was seen in seven patients (11.47%)
Conclusion: Early reporting (< 2weeks) of NAAION cases in a tertiary institute of northeast India was found to be low in the study. Macular edema in isolated cases was important where additional treatment was required. Lifestyle modifications of avoiding smoking and tobacco can be suggested in substance abuse cases.
Figure 1
Figure 2
Figure 3
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