A recent study examined toothbrushes to understand how microbes from our bodies interact with our environment. Toothbrushes are a unique component of the built environment that comes into daily contact with our bodies and water. Researchers characterized the metagenomes of toothbrushes from 34 individuals and found that toothbrush microbiomes resemble microbial communities in the mouth. Toothbrush-associated microbes were less diverse than those in people's mouths, but they had broader antimicrobial resistance gene (ARG) profiles, and microbial community makeup correlated with factors linked to personal health, dental hygiene, and bathroom features. Although this small pilot study must be expanded to confirm the findings, these results suggest that microbes on the surfaces we touch are affected by our health and behavior and that understanding how we can influence these microbes will help us make better decisions about cleaning and maintenance to promote a healthy environment.