Association of Oral Microbiota with Sugar-Sweetened Beverages Consumption and Oral Health Problems in School-Aged Children
Consumption of beverages is prevalent among children and adolescents, of which the most popular beverages were sugar-sweetened beverages (SSBs). There is evidence that common beverage consumption, like coffee and tea, is associated with oral ecosystem. However, little is known about the effect of SSBs on the composition and functional potential of childhood oral microbiota.To examine the associations between SSBs consumption with oral microbiota diversity among school-aged children.Data came from the fourth wave follow-up of an ongoing child growth and development cohort established in 2016. Oral microbiota in buccal cheek swab samples were collected from 180 children (78 boys and 112 girls, aged 11.33±0.55 years old) using 16S rDNA gene sequencing. Students’ questionnaire was used to collect SSB consumption. Oral health problems, such as dental caries, gingivitis, was examined by a professional dentist. Higher SSBs consumption (≥ 1 serving/week) was associated with lower oral microbiota richness and diversity. Children with higher SSBs consumption showed altered abundance of several oral microbiota at genus level, including increases in Streptococcus, Gemella, Neisseria,Capnocytophaga and Lautropia (and decreases in Fusobacterium, Lachnoanaerobaculum, Soonwooa, Tannerella and Moraxella (p< 0.05). Functional analysis illustrated that oral microbiota was more conducive to the pathway activated of lysine biosynthesis (p=0.045), protein export (p=0.020), D-glutamine and D-glutamate metabolism (p=0.013), as well as pantothenate and CoA biosynthesis (p=0.004) in children with higher SSBs intake. Our finding suggests that higher SSBs consumption may disturb oral microecology and reduce diversity and abundance of oral microbiota during childhood.
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Posted 13 May, 2020
Association of Oral Microbiota with Sugar-Sweetened Beverages Consumption and Oral Health Problems in School-Aged Children
Posted 13 May, 2020
Consumption of beverages is prevalent among children and adolescents, of which the most popular beverages were sugar-sweetened beverages (SSBs). There is evidence that common beverage consumption, like coffee and tea, is associated with oral ecosystem. However, little is known about the effect of SSBs on the composition and functional potential of childhood oral microbiota.To examine the associations between SSBs consumption with oral microbiota diversity among school-aged children.Data came from the fourth wave follow-up of an ongoing child growth and development cohort established in 2016. Oral microbiota in buccal cheek swab samples were collected from 180 children (78 boys and 112 girls, aged 11.33±0.55 years old) using 16S rDNA gene sequencing. Students’ questionnaire was used to collect SSB consumption. Oral health problems, such as dental caries, gingivitis, was examined by a professional dentist. Higher SSBs consumption (≥ 1 serving/week) was associated with lower oral microbiota richness and diversity. Children with higher SSBs consumption showed altered abundance of several oral microbiota at genus level, including increases in Streptococcus, Gemella, Neisseria,Capnocytophaga and Lautropia (and decreases in Fusobacterium, Lachnoanaerobaculum, Soonwooa, Tannerella and Moraxella (p< 0.05). Functional analysis illustrated that oral microbiota was more conducive to the pathway activated of lysine biosynthesis (p=0.045), protein export (p=0.020), D-glutamine and D-glutamate metabolism (p=0.013), as well as pantothenate and CoA biosynthesis (p=0.004) in children with higher SSBs intake. Our finding suggests that higher SSBs consumption may disturb oral microecology and reduce diversity and abundance of oral microbiota during childhood.
Figure 1
Figure 2
Figure 3