This preprint is under consideration at Health and Quality of Life Outcomes. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research
Md. Ziaul Isam
National Institute of Preventive and Social Medicine
Corresponding Author
ORCiD: https://orcid.org/0000-0002-5582-2402
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: The pandemic coronavirus disease 2019 (COVID-19) stances an incredible impact on the quality of life of the patients. The disease not only denigrates the physical health of the patients but also affects their mental health. This cross-sectional study aimed to assess the health-related quality of life (HRQOL) of patients.
Methods: The study was conducted at the National Institute of Preventive and Social Medicine (NIPSOM), Dhaka, Bangladesh during the period from June to November 2020. The study enrolled 1204 adult (>18 years) COVID-19 patients diagnosed by real-time reverse transcriptase-polymerase chain reaction (RT-PCR) assay and completed the one-month duration of illness. The patients were interviewed with the CDC HRQOL-14 questionnaire to assess their HRQOL. The questionnaire contains three modules: the healthy days' core; the activity limitations; and the healthy days’ symptoms. Data were collected by telephone-interview and reviewing medical records using a semi-structured questionnaire and checklist respectively. Informed consent was obtained from each patient before data collection.
Results: The majority of the COVID-19 patients were males (72.3%), urban residents (50.2%), and diverse service holders (49.6%). More than one-third (35.5%) of patients had comorbidity including hypertension (55.6%), diabetes mellitus (55.6%), ischaemic heart disease (16.4%), chronic lung (12.4%), kidney (2.8%), and liver (4.2%) diseases. During the one-month disease course, the majority (70.1%) of the patients had excellent/very good/good general health condition while 29.8% of the patients had fair/poor condition. The mean±SD duration of physical illness was 9.83(±7.09) days, and it was 7.97(±8.12) days for mental illness. Older age, females, and married patients were significantly associated with mean duration of diverse dimension of HRQOL. Fair/poor health condition was significantly associated with having a symptom (OR=33.22, CI=8.17-135.1) and having any comorbidity (OR=1.573, CI=1.18-2.10).
Conclusion: COVID-19 pretenses a significant impact on the HRQOL of the patients including physical and mental illness during the clinical course. Our findings suggest more pragmatic preventive, promotive, and curative measures considering illness experiences of the COVID-19 patients to restore their general health, quality of life, and daily activities.
Keywords
COVID-19 patients, HRQOL, Illness experience, Physical health, Mental health, Activity limitations, Bangladesh
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This preprint is under consideration at Health and Quality of Life Outcomes. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research
Md. Ziaul Isam
National Institute of Preventive and Social Medicine
Corresponding Author
ORCiD: https://orcid.org/0000-0002-5582-2402
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 12 Mar, 2021
No community comments so far
Review #? received
Received 15 Mar, 2021
Reviewer #1 agreed
On 15 Mar, 2021
Reviewers invited
Invitations sent on 12 Mar, 2021
Submission checks complete
On 02 Mar, 2021
Editor invited
On 02 Mar, 2021
Editor assigned
On 01 Mar, 2021
First submitted
On 01 Mar, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Health Economics & Outcomes Research
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: The pandemic coronavirus disease 2019 (COVID-19) stances an incredible impact on the quality of life of the patients. The disease not only denigrates the physical health of the patients but also affects their mental health. This cross-sectional study aimed to assess the health-related quality of life (HRQOL) of patients.
Methods: The study was conducted at the National Institute of Preventive and Social Medicine (NIPSOM), Dhaka, Bangladesh during the period from June to November 2020. The study enrolled 1204 adult (>18 years) COVID-19 patients diagnosed by real-time reverse transcriptase-polymerase chain reaction (RT-PCR) assay and completed the one-month duration of illness. The patients were interviewed with the CDC HRQOL-14 questionnaire to assess their HRQOL. The questionnaire contains three modules: the healthy days' core; the activity limitations; and the healthy days’ symptoms. Data were collected by telephone-interview and reviewing medical records using a semi-structured questionnaire and checklist respectively. Informed consent was obtained from each patient before data collection.
Results: The majority of the COVID-19 patients were males (72.3%), urban residents (50.2%), and diverse service holders (49.6%). More than one-third (35.5%) of patients had comorbidity including hypertension (55.6%), diabetes mellitus (55.6%), ischaemic heart disease (16.4%), chronic lung (12.4%), kidney (2.8%), and liver (4.2%) diseases. During the one-month disease course, the majority (70.1%) of the patients had excellent/very good/good general health condition while 29.8% of the patients had fair/poor condition. The mean±SD duration of physical illness was 9.83(±7.09) days, and it was 7.97(±8.12) days for mental illness. Older age, females, and married patients were significantly associated with mean duration of diverse dimension of HRQOL. Fair/poor health condition was significantly associated with having a symptom (OR=33.22, CI=8.17-135.1) and having any comorbidity (OR=1.573, CI=1.18-2.10).
Conclusion: COVID-19 pretenses a significant impact on the HRQOL of the patients including physical and mental illness during the clinical course. Our findings suggest more pragmatic preventive, promotive, and curative measures considering illness experiences of the COVID-19 patients to restore their general health, quality of life, and daily activities.
Figure 1
Figure 2
Figure 3
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