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Research Article
Louise Lundborg
Karolinska Institutet
Corresponding Author
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To evaluate associations between early-pregnancy Body Mass Index (BMI) and active first stage labour duration, accounting for possible interaction with maternal age, we conducted a cohort study of women with spontaneous onset of labour allocated to Robson group 1. Quantile regression analysis was performed to estimate first stage labour duration between BMI categories in two maternal age subgroups (more and less than 30 years). Results show that obesity (BMI > 30) among younger women (< 30 years) increased the median labour duration of first stage by 30 minutes compared with normal weight women (BMI < 25), and time difference estimated at the 90 th quantile was more than one hour. Active first stage labour time differences between obese and normal weight women was modified by maternal age. In conclusion: a) obesity is associated with longer duration of first stage of labour, and b) maternal age is an effect modifier for this association. This novel finding of an effect modification between BMI and maternal age contributes to the body of evidence that supports a more individualized approach when describing labour duration.
Keywords
Body Mass Index (BMI), maternal age, first stage duration of labour
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The full text of this article is available to read as a PDF.
No competing interests reported.
This is a list of supplementary files associated with this preprint. Click to download.
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View the published article at Scientific Reports.
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Posted 16 Mar, 2021
No community comments so far
Editorial decision: Major revision
On 21 May, 2021
Reviews received
Received 11 May, 2021
Reviewers agreed
On 26 Apr, 2021
Reviewers invited
Invitations sent on 09 Apr, 2021
Editor assigned
On 09 Apr, 2021
Editor invited
On 15 Mar, 2021
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On 15 Mar, 2021
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On 02 Mar, 2021
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A new preprint design is coming!
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See the published version of this preprint at Scientific Reports.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Louise Lundborg
Karolinska Institutet
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at Scientific Reports.
Version 1
Posted 16 Mar, 2021
No community comments so far
Editorial decision: Major revision
On 21 May, 2021
Reviews received
Received 11 May, 2021
Reviewers agreed
On 26 Apr, 2021
Reviewers invited
Invitations sent on 09 Apr, 2021
Editor assigned
On 09 Apr, 2021
Editor invited
On 15 Mar, 2021
Submission checks complete
On 15 Mar, 2021
First submitted
On 02 Mar, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at Scientific Reports.
To evaluate associations between early-pregnancy Body Mass Index (BMI) and active first stage labour duration, accounting for possible interaction with maternal age, we conducted a cohort study of women with spontaneous onset of labour allocated to Robson group 1. Quantile regression analysis was performed to estimate first stage labour duration between BMI categories in two maternal age subgroups (more and less than 30 years). Results show that obesity (BMI > 30) among younger women (< 30 years) increased the median labour duration of first stage by 30 minutes compared with normal weight women (BMI < 25), and time difference estimated at the 90 th quantile was more than one hour. Active first stage labour time differences between obese and normal weight women was modified by maternal age. In conclusion: a) obesity is associated with longer duration of first stage of labour, and b) maternal age is an effect modifier for this association. This novel finding of an effect modification between BMI and maternal age contributes to the body of evidence that supports a more individualized approach when describing labour duration.
Figure 1
The full text of this article is available to read as a PDF.
No competing interests reported.
This is a list of supplementary files associated with this preprint. Click to download.
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