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Sang Min Park
Pusan National University
Corresponding Author
ORCiD: https://orcid.org/0000-0002-2496-4141
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Electrospinning is a common and versatile process to produce nanofibers and deposit them on a collector as a two-dimensional nanofiber mat or a three-dimensional (3D) macroscopic arrangement. However, 3D electroconductive collectors with complex geometries, including protruded, curved, and recessed regions, generally caused hampering of a conformal deposition and incomplete covering of electrospun nanofibers. In this study, we suggested a conformal fabrication of an electrospun nanofiber mat on a 3D ear cartilage-shaped hydrogel collector based on hydrogel-assisted electrospinning. To relieve the influence of the complex geometries, we flattened the protruded parts of the 3D ear cartilage-shaped hydrogel collector by exploiting the flexibility of the hydrogel. We found that the suggested fabrication technique could significantly decrease an unevenly focused electric field, caused by the complex geometries of the 3D collector, by alleviating the standard deviation by more than 70% through numerical simulation. Furthermore, it was experimentally confirmed that an electrospun nanofiber mat conformally covered the flattened hydrogel collector with a uniform thickness, which was not achieved with the original hydrogel collector. Given that this study established the conformal electrospinning technique on 3D electroconductive collectors, it will contribute to various studies related to electrospinning, including tissue engineering, drug/cell delivery, environmental filter, and clothing.
Keywords
Electrospinning, nanofiber, hydrogel, 3D Printing, ear cartilage
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View the published article at Nanoscale Research Letters.
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Posted 17 Mar, 2021
No community comments so far
Editorial decision: Minor revision
On 01 Jun, 2021
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Received 31 May, 2021
Reviewer #2 agreed
On 18 May, 2021
Review #1 received
Received 16 May, 2021
Reviews received
Received 05 May, 2021
Reviewer #1 agreed
On 05 May, 2021
Reviewers invited
Invitations sent on 11 Mar, 2021
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On 01 Mar, 2021
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On 28 Feb, 2021
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A new preprint design is coming!
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See the published version of this preprint at Nanoscale Research Letters.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Nano Express
Sang Min Park
Pusan National University
Corresponding Author
ORCiD: https://orcid.org/0000-0002-2496-4141
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at Nanoscale Research Letters.
Version 1
Posted 17 Mar, 2021
No community comments so far
Editorial decision: Minor revision
On 01 Jun, 2021
Review #2 received
Received 31 May, 2021
Reviewer #2 agreed
On 18 May, 2021
Review #1 received
Received 16 May, 2021
Reviews received
Received 05 May, 2021
Reviewer #1 agreed
On 05 May, 2021
Reviewers invited
Invitations sent on 11 Mar, 2021
First submitted
On 01 Mar, 2021
Editor assigned
On 28 Feb, 2021
Submission checks complete
On 28 Feb, 2021
Editor invited
On 28 Feb, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at Nanoscale Research Letters.
Electrospinning is a common and versatile process to produce nanofibers and deposit them on a collector as a two-dimensional nanofiber mat or a three-dimensional (3D) macroscopic arrangement. However, 3D electroconductive collectors with complex geometries, including protruded, curved, and recessed regions, generally caused hampering of a conformal deposition and incomplete covering of electrospun nanofibers. In this study, we suggested a conformal fabrication of an electrospun nanofiber mat on a 3D ear cartilage-shaped hydrogel collector based on hydrogel-assisted electrospinning. To relieve the influence of the complex geometries, we flattened the protruded parts of the 3D ear cartilage-shaped hydrogel collector by exploiting the flexibility of the hydrogel. We found that the suggested fabrication technique could significantly decrease an unevenly focused electric field, caused by the complex geometries of the 3D collector, by alleviating the standard deviation by more than 70% through numerical simulation. Furthermore, it was experimentally confirmed that an electrospun nanofiber mat conformally covered the flattened hydrogel collector with a uniform thickness, which was not achieved with the original hydrogel collector. Given that this study established the conformal electrospinning technique on 3D electroconductive collectors, it will contribute to various studies related to electrospinning, including tissue engineering, drug/cell delivery, environmental filter, and clothing.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
The full text of this article is available to read as a PDF.
This is a list of supplementary files associated with this preprint. Click to download.
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