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Research
Mehmet Ali Yesıltas
Bakırköy Dr.Sadi Konuk Training and Research Hospital
Corresponding Author
ORCiD: https://orcid.org/0000-0002-5208-0626
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This work is licensed under a CC BY 4.0 License. Read Full License
Background and Aim: Atherosclerosis is a chronic inflammatory event that characterized by stiffness and thickening of the vascular walls. In our daily practice, we assume the atherosclerotic potential of the patient by following the total cholesterol, HDL, LDL and triglyceride levels (Lipids panel). We aimed to understand the relation between the HDL, LDL, cholesterol levels and the atherosclerosis in large vascular structures such as ascending aorta.
Methods: We have searched for atherosclerosis in the aortic tissue samples with 48 patients. It is a study in which we examine the correlation of preoperative cholesterol values (HDL, LDL, triglyceride, total cholesterol) by dividing the patients into two groups according to the presence of plaque.
Results: 43 males (89.6%), and 5 females (10.4%) patients between 39 and 81 years of age were included in the study. There was no statistically significant difference between the patients' preoperative cardiovascular risk assessments. The free T3 values were within the normal range with of all patients, however there was a difference that patients in the non-atherosclerosis group have lower values. There was no statistically significant difference between two groups' HDL, LDL, total cholesterol, triglyceride parameters.
Conclusion: As a result, in our study, no significant difference was found between HDL-C, LDL-C, triglyceride, total cholesterol values and the pathological process of aortic atherosclerosis. As a result of this study, we believe that it was necessary to correct the error margins of these parameters. In addition, it required the need for a clearer laboratory parameter to demonstrate atherosclerosis.
Keywords
Lipoproteins , Atherosclerosis , LDL Cholesterol
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A new preprint design is coming!
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research
Mehmet Ali Yesıltas
Bakırköy Dr.Sadi Konuk Training and Research Hospital
Corresponding Author
ORCiD: https://orcid.org/0000-0002-5208-0626
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 19 May, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background and Aim: Atherosclerosis is a chronic inflammatory event that characterized by stiffness and thickening of the vascular walls. In our daily practice, we assume the atherosclerotic potential of the patient by following the total cholesterol, HDL, LDL and triglyceride levels (Lipids panel). We aimed to understand the relation between the HDL, LDL, cholesterol levels and the atherosclerosis in large vascular structures such as ascending aorta.
Methods: We have searched for atherosclerosis in the aortic tissue samples with 48 patients. It is a study in which we examine the correlation of preoperative cholesterol values (HDL, LDL, triglyceride, total cholesterol) by dividing the patients into two groups according to the presence of plaque.
Results: 43 males (89.6%), and 5 females (10.4%) patients between 39 and 81 years of age were included in the study. There was no statistically significant difference between the patients' preoperative cardiovascular risk assessments. The free T3 values were within the normal range with of all patients, however there was a difference that patients in the non-atherosclerosis group have lower values. There was no statistically significant difference between two groups' HDL, LDL, total cholesterol, triglyceride parameters.
Conclusion: As a result, in our study, no significant difference was found between HDL-C, LDL-C, triglyceride, total cholesterol values and the pathological process of aortic atherosclerosis. As a result of this study, we believe that it was necessary to correct the error margins of these parameters. In addition, it required the need for a clearer laboratory parameter to demonstrate atherosclerosis.
Figure 1
Figure 2
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