With the technological revolution, the Internet of medical things (IoMT) has developed to be of immense benefit. Its aid is used in a wide range of medical image transmission. During the transmission of medical images, an ideal transaction should not jeopardize the security, confidentiality, authenticity, authorization, or integrity of sensitive data. This paper proposes a blind watermarking approach to address these issues. This strategy aims to protect the medical image’s Region of Interest (RoI) against manipulation throughout the transmission. The RoI of a medical image must be safeguarded in order to avoid incorrect diagnosis. Therefore, localized tamper detection and recovery bits generated for RoI to retrieve the original image in the occurrence of tampering. For ease of diagnosis, the patient’s health information, as well as the tamper recovery bits, are encoded in the medical image’s Region of Non-Interest (RoNI). Embedding information in RoNI validates imperceptibility. Additionally, to maintain Electronic Hospital Record (EHR) confidentiality, the Magic Square technique is used to encrypt the EHR. The robustness performance of the scheme proposed here is analyzed under different image processing attacks. The experimental results shows that the proposed scheme enables realtime and lossless image transmission via IoMT.