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Research article
Hongmei Liu
Department of Ultrasound, Institute of Ultrasound in Musculoskeletal Sports Medicine, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, P.R.China Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, P.R.
Corresponding Author
ORCiD: https://orcid.org/0000-0002-0641-7611
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Background: to evaluate the correlation between spontaneous conception outcome and the patients’ clinical characteristics as well as tubal patency in infertile women after four-dimensional hysterosalpingo-contrast sonography (4D-HyCoSy).
Methods:Two hundred and eighty three infertile patients performed 4D-HyCoSy between December 2014 and October 2017,based on a normal semen analysis according to World Health Organization criteria, spontaneous conception without clinical interventions after 4D-HyCoSy, were trying to become conception. We analyzed the relationship between spontaneous conception outcome and clinical characteristics and tubal patency of infertile women after 4D-HyCoSy.
Result(s): One hundred and sixteen patients (40.9%) conceived spontaneously and the mean conception time was (8.8 ± 0.3) months. With Cox regression analysis, two factors associated with spontaneous conception outcome appeared to increase spontaneous conception rate: patients with type IV or type VI tubes and duration of infertility less than 2 years.The age, type of infertility, multiparas, history of pelvic surgery, history of uterine cavity operation, uterine fibromyomata and polycystic ovary were unrelated to spontaneous conception outcome after 4D-HyCoSy.
Conclusion(s):This study showed that some infertile women could succeed in spontaneous conception after 4D-HyCoSy. Hence, infertile patients should be advised to accept 4D-HyCoSy examination as soon as possible and based on the 4D-HyCoSy they could chose the appropriate clinical intervention. According to the results, expectant treatment of about 8-9 months is reported to be feasible for infertile women whose 4D-HyCoSy findings showed one tube patency or poor patency, especially for those with bilateral tubes patency or bilateral tubes poor patency.Alternatively, an immediate clinical intervention is recommended for those with bilateralobstructed tubes.
Keywords
conception, infertility, fallopian tubal patency, sonography
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CURRENT STATUS: Published
View the published article at BMC Pregnancy and Childbirth.
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On 06 Oct, 2020
Editorial decision: Accept
On 05 Oct, 2020
No comments provided
Editorial decision: Minor revision
On 29 Sep, 2020
Editor assigned
On 27 Sep, 2020
Editor invited
On 26 Sep, 2020
Submission checks complete
On 26 Sep, 2020
Version (no preprint)
Posted 29 Sep, 2020
Editor assigned
On 01 Oct, 2020
Submission checks complete
On 30 Sep, 2020
Editor invited
On 30 Sep, 2020
This version was not preprinted
No comments provided
Editorial decision: Major revision
On 02 Sep, 2020
Editor assigned
On 01 Sep, 2020
Submission checks complete
On 31 Aug, 2020
Editor invited
On 31 Aug, 2020
No comments provided
Editorial decision: Major revision
On 10 Aug, 2020
Editor assigned
On 03 Aug, 2020
Editor invited
On 02 Aug, 2020
Submission checks complete
On 30 Jul, 2020
Version 1
Posted 21 May, 2020
No comments provided
Review #1 received
Received 09 Jul, 2020
Editorial decision: Major revision
On 09 Jul, 2020
Review #2 received
Received 26 Jun, 2020
Reviewer #2 agreed
On 25 Jun, 2020
Reviewer #1 agreed
On 15 Jun, 2020
Reviewers invited
Invitations sent on 10 Jun, 2020
First submitted
On 18 May, 2020
Editor assigned
On 18 May, 2020
Submission checks complete
On 17 May, 2020
Editor invited
On 17 May, 2020
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Subject Areas
Maternal & Fetal Medicine
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A new preprint design is coming!
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See the published version of this preprint at BMC Pregnancy and Childbirth.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research article
Hongmei Liu
Department of Ultrasound, Institute of Ultrasound in Musculoskeletal Sports Medicine, Guangdong Second Provincial General Hospital, Guangzhou, Guangdong, P.R.China Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, P.R.
Corresponding Author
ORCiD: https://orcid.org/0000-0002-0641-7611
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at BMC Pregnancy and Childbirth.
No community comments so far
Submission checks complete
On 06 Oct, 2020
Editorial decision: Accept
On 05 Oct, 2020
No comments provided
Editorial decision: Minor revision
On 29 Sep, 2020
Editor assigned
On 27 Sep, 2020
Editor invited
On 26 Sep, 2020
Submission checks complete
On 26 Sep, 2020
Version (no preprint)
Posted 29 Sep, 2020
Editor assigned
On 01 Oct, 2020
Submission checks complete
On 30 Sep, 2020
Editor invited
On 30 Sep, 2020
This version was not preprinted
No comments provided
Editorial decision: Major revision
On 02 Sep, 2020
Editor assigned
On 01 Sep, 2020
Submission checks complete
On 31 Aug, 2020
Editor invited
On 31 Aug, 2020
No comments provided
Editorial decision: Major revision
On 10 Aug, 2020
Editor assigned
On 03 Aug, 2020
Editor invited
On 02 Aug, 2020
Submission checks complete
On 30 Jul, 2020
Version 1
Posted 21 May, 2020
No comments provided
Review #1 received
Received 09 Jul, 2020
Editorial decision: Major revision
On 09 Jul, 2020
Review #2 received
Received 26 Jun, 2020
Reviewer #2 agreed
On 25 Jun, 2020
Reviewer #1 agreed
On 15 Jun, 2020
Reviewers invited
Invitations sent on 10 Jun, 2020
First submitted
On 18 May, 2020
Editor assigned
On 18 May, 2020
Submission checks complete
On 17 May, 2020
Editor invited
On 17 May, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Maternal & Fetal Medicine
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at BMC Pregnancy and Childbirth.
Background: to evaluate the correlation between spontaneous conception outcome and the patients’ clinical characteristics as well as tubal patency in infertile women after four-dimensional hysterosalpingo-contrast sonography (4D-HyCoSy).
Methods:Two hundred and eighty three infertile patients performed 4D-HyCoSy between December 2014 and October 2017,based on a normal semen analysis according to World Health Organization criteria, spontaneous conception without clinical interventions after 4D-HyCoSy, were trying to become conception. We analyzed the relationship between spontaneous conception outcome and clinical characteristics and tubal patency of infertile women after 4D-HyCoSy.
Result(s): One hundred and sixteen patients (40.9%) conceived spontaneously and the mean conception time was (8.8 ± 0.3) months. With Cox regression analysis, two factors associated with spontaneous conception outcome appeared to increase spontaneous conception rate: patients with type IV or type VI tubes and duration of infertility less than 2 years.The age, type of infertility, multiparas, history of pelvic surgery, history of uterine cavity operation, uterine fibromyomata and polycystic ovary were unrelated to spontaneous conception outcome after 4D-HyCoSy.
Conclusion(s):This study showed that some infertile women could succeed in spontaneous conception after 4D-HyCoSy. Hence, infertile patients should be advised to accept 4D-HyCoSy examination as soon as possible and based on the 4D-HyCoSy they could chose the appropriate clinical intervention. According to the results, expectant treatment of about 8-9 months is reported to be feasible for infertile women whose 4D-HyCoSy findings showed one tube patency or poor patency, especially for those with bilateral tubes patency or bilateral tubes poor patency.Alternatively, an immediate clinical intervention is recommended for those with bilateralobstructed tubes.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
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