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Research Article
Habtye Bisetegn
Wollo University
Corresponding Author
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Background
Schistosomiasis is a neglected tropical disease caused by mainly Schistosoma mansoni and Schistosoma hematobium. The disease is very common in Africa including Ethiopia. Schistosoma mansoni is a major public health problem in Ethiopia especially among children. This review is aimed to indicate the prevalence of Schistosoma mansoni among children at national and regional level.
Methods and material:
The PRISMA guidelines were followed. Electronic search of PubMed, Google Scholar, Web of Science, Scopus, MEDLINE and Google search were carried out using key terms. Articles published from the proceeding of professional associations such as Ethiopian medical laboratory association, Ethiopian public health association and annual national research conferences were searched to find eligible studies. Data was extracted independently by two investigators, and pooled using a random effects model. Data was extracted using Microsoft excel and final analyzed using STATA version 12. Quality of included studies was assessed using JBI quality assessment criteria.
Result
Over all 41 studies involving 15968 children were included in this meta-analysis. The pooled prevalence of Schistosoma mansoni infection was 37.75% (95%CI:29.97–45.53). High heterogeneity was observed with I2 of 99.3%, p = 0.000. According to subgroup analysis, the pooled prevalence was high in SNNPR (46.27%: 95%CI: 21.77–70.77) followed by Amhara region (41.9%: 95%CI: 28.45–54.54) Tigray region (38.14%: 95%CI:24.22–52.05) and Oromia region (26.54%: 95%CI: 16.89–36.20). Year from 2011 to 2015 contribute for the highest prevalence of Schistosoma mansoni among children (44.46% (95%:30.88–58.03).
Conclusion
This study revealed 37.75% Schistosoma mansoni infection among children. High prevalence of schistosomes among children highlights the importance of improving and implementing appropriate control strategies such as mass drug administration in Ethiopia.
Keywords
Schistosomiasis, Schistosoma mansoni, Children and Ethiopia
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CURRENT STATUS: Published
View the published article at Tropical Diseases, Travel Medicine and Vaccines.
Version 1
Posted 01 Jun, 2021
No community comments so far
Editorial decision: Major revision
On 25 Jun, 2021
Review #4 received
Received 21 Jun, 2021
Review #3 received
Received 15 Jun, 2021
Review #2 received
Received 14 Jun, 2021
Reviewer #4 agreed
On 29 May, 2021
Reviewer #3 agreed
On 19 May, 2021
Reviewer #2 agreed
On 17 May, 2021
Review #1 received
Received 05 Apr, 2021
Reviews received
Received 24 Mar, 2021
Reviewer #1 agreed
On 24 Mar, 2021
Reviewers invited
Invitations sent on 21 Mar, 2021
Editor assigned
On 10 Mar, 2021
Submission checks complete
On 10 Mar, 2021
Editor invited
On 10 Mar, 2021
First submitted
On 05 Mar, 2021
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A new preprint design is coming!
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See the published version of this preprint at Tropical Diseases, Travel Medicine and Vaccines.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Habtye Bisetegn
Wollo University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at Tropical Diseases, Travel Medicine and Vaccines.
Version 1
Posted 01 Jun, 2021
No community comments so far
Editorial decision: Major revision
On 25 Jun, 2021
Review #4 received
Received 21 Jun, 2021
Review #3 received
Received 15 Jun, 2021
Review #2 received
Received 14 Jun, 2021
Reviewer #4 agreed
On 29 May, 2021
Reviewer #3 agreed
On 19 May, 2021
Reviewer #2 agreed
On 17 May, 2021
Review #1 received
Received 05 Apr, 2021
Reviews received
Received 24 Mar, 2021
Reviewer #1 agreed
On 24 Mar, 2021
Reviewers invited
Invitations sent on 21 Mar, 2021
Editor assigned
On 10 Mar, 2021
Submission checks complete
On 10 Mar, 2021
Editor invited
On 10 Mar, 2021
First submitted
On 05 Mar, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at Tropical Diseases, Travel Medicine and Vaccines.
Background
Schistosomiasis is a neglected tropical disease caused by mainly Schistosoma mansoni and Schistosoma hematobium. The disease is very common in Africa including Ethiopia. Schistosoma mansoni is a major public health problem in Ethiopia especially among children. This review is aimed to indicate the prevalence of Schistosoma mansoni among children at national and regional level.
Methods and material:
The PRISMA guidelines were followed. Electronic search of PubMed, Google Scholar, Web of Science, Scopus, MEDLINE and Google search were carried out using key terms. Articles published from the proceeding of professional associations such as Ethiopian medical laboratory association, Ethiopian public health association and annual national research conferences were searched to find eligible studies. Data was extracted independently by two investigators, and pooled using a random effects model. Data was extracted using Microsoft excel and final analyzed using STATA version 12. Quality of included studies was assessed using JBI quality assessment criteria.
Result
Over all 41 studies involving 15968 children were included in this meta-analysis. The pooled prevalence of Schistosoma mansoni infection was 37.75% (95%CI:29.97–45.53). High heterogeneity was observed with I2 of 99.3%, p = 0.000. According to subgroup analysis, the pooled prevalence was high in SNNPR (46.27%: 95%CI: 21.77–70.77) followed by Amhara region (41.9%: 95%CI: 28.45–54.54) Tigray region (38.14%: 95%CI:24.22–52.05) and Oromia region (26.54%: 95%CI: 16.89–36.20). Year from 2011 to 2015 contribute for the highest prevalence of Schistosoma mansoni among children (44.46% (95%:30.88–58.03).
Conclusion
This study revealed 37.75% Schistosoma mansoni infection among children. High prevalence of schistosomes among children highlights the importance of improving and implementing appropriate control strategies such as mass drug administration in Ethiopia.
Figure 1
Figure 2
Figure 3
Figure 4
This is a list of supplementary files associated with this preprint. Click to download.
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