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Protocol
Abay Woday
Samara University, College of Medicine and Health Sciences, Afar Region, Ethiopia.
Corresponding Author
ORCiD: https://orcid.org/0000-0003-0499-4690
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Birth asphyxia among newborns accounted for nearly fifty percent of neonatal mortality in sub-Saharan African countries. This scenario has been worst in Ethiopia where every two out of three deaths attributed to birth asphyxia among these babies. Moreover, studies conducted in Ethiopia are highly variable and inconclusive to estimate the pooled prevalence and risk factors of birth asphyxia.
Objective: This study aims to analyses collectively and systematically the prevalence of birth asphyxia and associated factors among newborns in Ethiopia.
Methods: The protocol for this review is registered at PROSPERO with registration number CRD42020158224. A comprehensive online databases (PubMed, HINARI, Scopus, EMBASE, Science direct, and Cochrane library database), Google Scholar, African Journals online, other gray and online repository accessed studies will be searched using different search engines. In addition, maternity & infant care databases uploaded at Ethiopian Health Development Journal and Ethiopian Journal of Health Sciences will be searched until June 30, 2020. Newcastle-Ottawa Quality Assessment Scale (NOS) will be used for critical appraisal of studies.. Three reviewers will screen all retrieved articles, conduct data extraction, and then critically appraise all identified studies. All identified observational studies reporting the prevalence of birth asphyxia and associated factors among neonates in Ethiopia will be considered. The analysis of data will be done using STATA 11.0 statistical software. We will demonstrate pooled estimates and determinants of birth asphyxia with effect size and 95% confidence interval. Heterogeneity among the included studies will be assessed through the Cochrane Q-test statistics and I2 test. Publication bias will be checked using funnel plot and egger’s test. Finally, statistical significance level will be declared at a p-value of less than 0.05.
Discussion: the result from this systematic review will inform and guide health policy planners to invest limited resources on maternal and neonatal health. Furthermore, it will be a stimulus for future cumulative meta-analysis researchers in developing nations.
Keywords
newborns, meta-analysis, birth asphyxia, difficulty of breathing at birth, associated factors, neonates, Ethiopia
This is a list of supplementary files associated with this preprint. Click to download.
- AdditionalFiles.pdf
Additional file 1: PRISMA-P 2015 checklist. Additional file 2: PubMed search string. Additional file 3: Articles screening checklist. Additional 4: Adapted Newcastle-Ottawa Quality Assessment Scale (NOS)
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Peer Review Timeline
CURRENT STATUS: Under Review
Version 2
Posted 30 Dec, 2020
No community comments so far
Review #2 received
Received 12 Jun, 2021
Reviews received
Received 10 Jun, 2021
Reviewer #2 agreed
On 10 Jun, 2021
Review #1 received
Received 03 Apr, 2021
Reviewer #1 agreed
On 06 Mar, 2021
Reviewers invited
Invitations sent on 30 Jan, 2021
Editor assigned
On 12 Dec, 2020
Submission checks complete
On 12 Dec, 2020
Editor invited
On 12 Dec, 2020
First submitted
On 10 Dec, 2020
Editorial decision: Major revision
On 09 Nov, 2020
No comments provided
Editorial decision: Major revision
On 08 Nov, 2020
Review #1 received
Received 27 Sep, 2020
Review #2 received
Received 23 Sep, 2020
Reviewer #2 agreed
On 10 Sep, 2020
Reviewer #1 agreed
On 31 Aug, 2020
Reviewers invited
Invitations sent on 06 Aug, 2020
Editor assigned
On 25 Jun, 2020
Editor invited
On 24 Jun, 2020
First submitted
On 20 May, 2020
Submission checks complete
On 20 May, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Health Policy
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A new preprint design is coming!
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This preprint is under consideration at Systematic Reviews. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Protocol
Abay Woday
Samara University, College of Medicine and Health Sciences, Afar Region, Ethiopia.
Corresponding Author
ORCiD: https://orcid.org/0000-0003-0499-4690
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 2
Posted 30 Dec, 2020
No community comments so far
Review #2 received
Received 12 Jun, 2021
Reviews received
Received 10 Jun, 2021
Reviewer #2 agreed
On 10 Jun, 2021
Review #1 received
Received 03 Apr, 2021
Reviewer #1 agreed
On 06 Mar, 2021
Reviewers invited
Invitations sent on 30 Jan, 2021
Editor assigned
On 12 Dec, 2020
Submission checks complete
On 12 Dec, 2020
Editor invited
On 12 Dec, 2020
First submitted
On 10 Dec, 2020
Editorial decision: Major revision
On 09 Nov, 2020
No comments provided
Editorial decision: Major revision
On 08 Nov, 2020
Review #1 received
Received 27 Sep, 2020
Review #2 received
Received 23 Sep, 2020
Reviewer #2 agreed
On 10 Sep, 2020
Reviewer #1 agreed
On 31 Aug, 2020
Reviewers invited
Invitations sent on 06 Aug, 2020
Editor assigned
On 25 Jun, 2020
Editor invited
On 24 Jun, 2020
First submitted
On 20 May, 2020
Submission checks complete
On 20 May, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Health Policy
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Birth asphyxia among newborns accounted for nearly fifty percent of neonatal mortality in sub-Saharan African countries. This scenario has been worst in Ethiopia where every two out of three deaths attributed to birth asphyxia among these babies. Moreover, studies conducted in Ethiopia are highly variable and inconclusive to estimate the pooled prevalence and risk factors of birth asphyxia.
Objective: This study aims to analyses collectively and systematically the prevalence of birth asphyxia and associated factors among newborns in Ethiopia.
Methods: The protocol for this review is registered at PROSPERO with registration number CRD42020158224. A comprehensive online databases (PubMed, HINARI, Scopus, EMBASE, Science direct, and Cochrane library database), Google Scholar, African Journals online, other gray and online repository accessed studies will be searched using different search engines. In addition, maternity & infant care databases uploaded at Ethiopian Health Development Journal and Ethiopian Journal of Health Sciences will be searched until June 30, 2020. Newcastle-Ottawa Quality Assessment Scale (NOS) will be used for critical appraisal of studies.. Three reviewers will screen all retrieved articles, conduct data extraction, and then critically appraise all identified studies. All identified observational studies reporting the prevalence of birth asphyxia and associated factors among neonates in Ethiopia will be considered. The analysis of data will be done using STATA 11.0 statistical software. We will demonstrate pooled estimates and determinants of birth asphyxia with effect size and 95% confidence interval. Heterogeneity among the included studies will be assessed through the Cochrane Q-test statistics and I2 test. Publication bias will be checked using funnel plot and egger’s test. Finally, statistical significance level will be declared at a p-value of less than 0.05.
Discussion: the result from this systematic review will inform and guide health policy planners to invest limited resources on maternal and neonatal health. Furthermore, it will be a stimulus for future cumulative meta-analysis researchers in developing nations.
This is a list of supplementary files associated with this preprint. Click to download.
- AdditionalFiles.pdf
Additional file 1: PRISMA-P 2015 checklist. Additional file 2: PubMed search string. Additional file 3: Articles screening checklist. Additional 4: Adapted Newcastle-Ottawa Quality Assessment Scale (NOS)
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