We present a Ground Motion Prediction Equation (GMPE) of peak ground acceleration (PGA) for the Gulf of California (GoC), Mexico derived from PGA values of 720 earthquakes recorded between 2015 and 2018 by the Red Sismológica de Banda Ancha del Golfo de California (RESBAN), operated by the Centro de Investigación Científica y de Educación Superior de Ensenada, Baja California (CICESE). We evaluated and adjusted two different parametric forms of GMPE developed for transcurrent tectonic regimes that resemble the tectonic setting in the GoC, along with an additional parametric form developed for central Mexico that incorporates the focal depth as an independent variable. All three adjustments exhibit appropriate behavior in terms of residual analysis and variables stability, with the parametrical form of Joyner and Boore (1981) providing the best overall performance. The proposed GMPE is: [[EQUATION]] Where PGA is peak horizontal acceleration in cm/s2, M is magnitude and d is epicentral distance. [[EQUATION]]A = 0.18 and [[EQUATION]]E = 0.4 correspond to the intra-event and inter-event standard deviations respectively. While the inclusion of focal depth as an independent variable has improved the adjustments in regions with different tectonic regimes, its incorporation did not provide any specific advantage in this case. The depth of the events was considered by incorporating a fixed value representing the average focal depth into the distance definition (11.86 km). This approach proved effective in capturing the seismic characteristics of the studied region, highlighting the importance of considering regional-specific factors when developing and refining GMPEs.