This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research article
Golaleh Asghari
Shahid Beheshti University of Medical Sciences
Corresponding Author
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Aims: To examine the association of dietary diabetes risk reduction score (DDRRS) with chronic kidney disease (CKD) among an Iranian population.
Methods: We followed-up 2076 ≥ 20 years old participants of Tehran Lipid and Glucose Study (2006-2008), who were initially free of CKD for 5.98 years. Dietary diabetes risk reduction score was calculated on the basis of scoring eight components using a valid and reliable 168-item food frequency questionnaire. CKD was defined as estimated glumerular filtration rate (eGFR) <60 mL/min/1.73 m2. A Cox proportional hazard regression model was used to assess association between the quartiles of DDRRS and incidence of CKD.
Results: Mean ± SD age of the study population (53% women) was 37.6 ± 12.61 years. A total of 357 incident cases of CKD were reported. The median (25-75 interquartile range) of DDRRS was 20 (18-22). After adjustment for age, sex, smoking status, total energy intake, body mass index, hypertension, diabetes, eGFR, and physical activity, individuals in the highest versus lowest quartile of DDRRS were 33% less likely to have CKD (OR: 0.67; 95% CI: 0.48-0.96, P for trend: 0.043).
Conclusion: Our findings suggest an inverse association between DDRRS and risk of incident CKD in the fourth versus first quartile of DDRRS.
Keywords
Chronic kidney disease, Dietary diabetes risk reduction score, Glomerular filtration rate
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research article
Golaleh Asghari
Shahid Beheshti University of Medical Sciences
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 01 Jun, 2020
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Nutrition & Dietetics
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Aims: To examine the association of dietary diabetes risk reduction score (DDRRS) with chronic kidney disease (CKD) among an Iranian population.
Methods: We followed-up 2076 ≥ 20 years old participants of Tehran Lipid and Glucose Study (2006-2008), who were initially free of CKD for 5.98 years. Dietary diabetes risk reduction score was calculated on the basis of scoring eight components using a valid and reliable 168-item food frequency questionnaire. CKD was defined as estimated glumerular filtration rate (eGFR) <60 mL/min/1.73 m2. A Cox proportional hazard regression model was used to assess association between the quartiles of DDRRS and incidence of CKD.
Results: Mean ± SD age of the study population (53% women) was 37.6 ± 12.61 years. A total of 357 incident cases of CKD were reported. The median (25-75 interquartile range) of DDRRS was 20 (18-22). After adjustment for age, sex, smoking status, total energy intake, body mass index, hypertension, diabetes, eGFR, and physical activity, individuals in the highest versus lowest quartile of DDRRS were 33% less likely to have CKD (OR: 0.67; 95% CI: 0.48-0.96, P for trend: 0.043).
Conclusion: Our findings suggest an inverse association between DDRRS and risk of incident CKD in the fourth versus first quartile of DDRRS.
Figure 1
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