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Research Article
Elyas Hosseinzadeh
Sirjan school of medical sciences
Corresponding Author
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This work is licensed under a CC BY 4.0 License. Read Full License
In this study, cerium oxide and multi-walled carbon nanotubes nanocomposite was incorporated into the carbon ceramic electrode (CeO2-MWCNTs/CCE) as a renewable electrode for the electrocatalytic purposes. To demonstrate capability of the fabricated electrode, determination of Tamoxifen as an important anticancer drug with differential pulse voltammetry technique was evaluated. Linear range, limit of detection and sensitivity of the developed sensor were found to be 0.2-40 nM, 0.132 nM and 1.478 µA nM-1 cm-2, respectively. Ease of production, low cost and high electron transfer rate of CeO2-MWCNTs/CCE promise it as a novel electro-analytical tool for determination of important species in real samples.
Keywords
Cerium oxide, MWCNTs, Renewable electrode, Tamoxifen, Electrochemical sensor
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This is a list of supplementary files associated with this preprint. Click to download.
- sfig1.jpg
XRD pattern of CeO2-MWCNT/CCE.
- sfig2.jpg
(A) CVs of bare-CCE in 0.01 M [Fe(CN)6]3− at 0.1 M acetate buffer solution in different scan rates of 10, 25, 50, 75, 100, 150, 200, 250, 300, 400 and 500 mV s-1; (B) Change of peak currents vs. square root of scan rate.
- sfig3.jpg
(A) CVs of CeO2-MWCNT/CCE in 0.01 M [Fe(CN)6]3− at 0.1 M acetate buffer solution in different scan rates of 10, 25, 50, 75, 100, 150, 200, 250, 300, 400 and 500 mV s-1; (B) Change of peak currents vs. square root of scan rate.
- sfig4.jpg
(A) CVs of CeO2-MWCNT/CCE in the presence of TAM with different concentrations of 4.5, 5, 5.5, 6, 6.5, 7, 7.5 and 8 µM. (B) The corresponding calibration curve.
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This is a preprint. It has not completed peer review.
Research Article
Elyas Hosseinzadeh
Sirjan school of medical sciences
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 23 Mar, 2021
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Materials Engineering
License:
This work is licensed under a CC BY 4.0 License. Read Full License
In this study, cerium oxide and multi-walled carbon nanotubes nanocomposite was incorporated into the carbon ceramic electrode (CeO2-MWCNTs/CCE) as a renewable electrode for the electrocatalytic purposes. To demonstrate capability of the fabricated electrode, determination of Tamoxifen as an important anticancer drug with differential pulse voltammetry technique was evaluated. Linear range, limit of detection and sensitivity of the developed sensor were found to be 0.2-40 nM, 0.132 nM and 1.478 µA nM-1 cm-2, respectively. Ease of production, low cost and high electron transfer rate of CeO2-MWCNTs/CCE promise it as a novel electro-analytical tool for determination of important species in real samples.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
Figure 6
Figure 7
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