Based on the land use data of Qianping Reservoir from 2000 to 2020 before and after the construction of Qianping Reservoir, this paper studies the spatial and temporal distribution and change characteristics of landscape pattern and ecological fragility of Qianping Reservoir, and analyzes the driving forces. The results showed (a) the dominant types of landscape were mainly cultivated land and forest land, and the area of construction land and water area increased steadily, while cultivated land showed a decreasing trend. (b) The vulnerability of the study area was mainly in the high vulnerability area and the medium vulnerability area, mainly distributed in the forest land and construction land area, but the overall pattern vulnerability showed a downward trend. Vulnerability is closely related to human activities, has a certain correlation with topography, and is not significantly affected by climate change, but it still reflects some problems. The research results provide a scientific basis for the landscape planning and construction of Qianping Reservoir to promote the sustainable development of the environment, and also provide a reference for the analysis of landscape vulnerability in similar areas.