This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Short Report
Samer Singh
Institute of Medical Sciences, Banaras Hindu University
Corresponding Author
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This work is licensed under a CC BY 4.0 License. Read Full License
Various studies are underway to identify protective variables for the COVID-19 pandemic. We hypothesized that if indeed the Vitamin D levels would be protective in the European population, as recently proposed, the correlation would become more robust when the countries had passed the infection peak as on May 12, 2020, compared to April 8, 2020, when the majority had not. Comparative analysis of data from the mentioned stages indicated a significant increase in negative correlation of vitamin D levels with COVID-19 cases per million population in later stage (r(20): -0.5504; R2=0.3029; p-value: 0.0119 vs r(20): -0.4435; R2=0.1967; p-value: 0.0501) whereas the correlation with deaths per million population became insignificant (r(20): -0.3935; R2=0.1549; p-value: 0.0860 vs r(20): -0.4378; R2=0.1917; p-value: 0.0535). Considering divergence of vitamin D levels from the mean in subgroups, e.g. children, women, aged, dedicated exploratory studies with carefully chosen matched target groups is advisable.
Keywords
COVID-19, SARS-CoV-2, Correlation, Vitamin D, Europe
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Short Report
Samer Singh
Institute of Medical Sciences, Banaras Hindu University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
View the published article at Aging Clinical and Experimental Research.
Version 1
Posted 01 Jun, 2020
Community comments: 3
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Infectious Diseases
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at Aging Clinical and Experimental Research.
Various studies are underway to identify protective variables for the COVID-19 pandemic. We hypothesized that if indeed the Vitamin D levels would be protective in the European population, as recently proposed, the correlation would become more robust when the countries had passed the infection peak as on May 12, 2020, compared to April 8, 2020, when the majority had not. Comparative analysis of data from the mentioned stages indicated a significant increase in negative correlation of vitamin D levels with COVID-19 cases per million population in later stage (r(20): -0.5504; R2=0.3029; p-value: 0.0119 vs r(20): -0.4435; R2=0.1967; p-value: 0.0501) whereas the correlation with deaths per million population became insignificant (r(20): -0.3935; R2=0.1549; p-value: 0.0860 vs r(20): -0.4378; R2=0.1917; p-value: 0.0535). Considering divergence of vitamin D levels from the mean in subgroups, e.g. children, women, aged, dedicated exploratory studies with carefully chosen matched target groups is advisable.
Figure 1
This is a list of supplementary files associated with this preprint. Click to download.
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