Density-dependent change in aggressive behavior is essential for regulating the population dynamics of many small rodents, but the underlying neurological mechanisms have not been examined in field conditions. We hypothesized that aggression-associated oxytocin (OT) and vasopressin (AVP) in specific regions of the brain may be closely related to aggressive behaviors and population changes of small rodents. In this study, we analyzed the associations of OT and AVP expression as well as aggressive behavior with population density of Brandt’s voles in 24 large semi-natural enclosures (0.48 ha for each enclosure) in Inner Mongolia grassland. Then we tested the effects of population density on the OT/AVP system and aggressive behavior in experimentally manipulated populations of Brandt’s voles in the semi-natural enclosures. High density was positively and significantly associated with more aggressive behavior, and increased expression of mRNA and protein of AVP and its receptor, but decreased expression of mRNA and protein of OT and its receptor in specific brain regions of the voles. Our study suggests that OT/AVP systems are important in regulating the density-dependent population dynamics via aggressive behavior of small rodents, and they can be used as indicators of population variation or density-dependent stressors.
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Posted 22 Mar, 2021
On 11 Apr, 2021
On 05 Apr, 2021
Received 05 Apr, 2021
Invitations sent on 26 Mar, 2021
On 15 Mar, 2021
On 15 Mar, 2021
On 15 Mar, 2021
On 15 Mar, 2021
Posted 22 Mar, 2021
On 11 Apr, 2021
On 05 Apr, 2021
Received 05 Apr, 2021
Invitations sent on 26 Mar, 2021
On 15 Mar, 2021
On 15 Mar, 2021
On 15 Mar, 2021
On 15 Mar, 2021
Density-dependent change in aggressive behavior is essential for regulating the population dynamics of many small rodents, but the underlying neurological mechanisms have not been examined in field conditions. We hypothesized that aggression-associated oxytocin (OT) and vasopressin (AVP) in specific regions of the brain may be closely related to aggressive behaviors and population changes of small rodents. In this study, we analyzed the associations of OT and AVP expression as well as aggressive behavior with population density of Brandt’s voles in 24 large semi-natural enclosures (0.48 ha for each enclosure) in Inner Mongolia grassland. Then we tested the effects of population density on the OT/AVP system and aggressive behavior in experimentally manipulated populations of Brandt’s voles in the semi-natural enclosures. High density was positively and significantly associated with more aggressive behavior, and increased expression of mRNA and protein of AVP and its receptor, but decreased expression of mRNA and protein of OT and its receptor in specific brain regions of the voles. Our study suggests that OT/AVP systems are important in regulating the density-dependent population dynamics via aggressive behavior of small rodents, and they can be used as indicators of population variation or density-dependent stressors.
Figure 1
Figure 2
Figure 3
Figure 4
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