This preprint is under consideration at a Nature Portfolio Journal. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Nature journals have partnered with Research Square to offer In Review, a journal-integrated preprint deposition service.
Article
Amir Rosenthal
Technion - Israel Institute of Technology
Corresponding Author
ORCiD: https://orcid.org/0000-0001-8077-7773
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Optical imaging is commonly performed with either a camera and wide-field illumination or with a single detector and a collimated beam that scans the imaged object. Unfortunately, sources that can be collimated and cameras do not exist at all wavelengths and may not always achieve the specifications required for a given application. Single-pixel imaging (SPI) offers an alternative that requires a single detector and may be performed with wide-field illumination, potentially enabling imaging applications in which both the detection and illumination technologies are immature. However, SPI currently struggles with low imaging rates owing to its reliance on configurable spatial light modulators, whose rates do not generally exceed 22 kHz. In this work, we develop an approach towards rapid SPI which relies on cyclic patterns coded onto a spinning mask and demonstrate it for in vivo imaging of C. elegans worms. Spatial modulation rates of up to 2.4 MHz and imaging rates of up to 72 fps are reported, creating new opportunities for using the SPI paradigm in dynamic imaging scenarios.
Keywords
Optical Imaging, Collimated Beams, Configurable Spatial Light Modulators, Dynamic Imaging Scenarios
Figure 1
Figure 2
Figure 3
Figure 4
There is NO Competing Interest.
This is a list of supplementary files associated with this preprint. Click to download.
- SupplementaryEH24.pdf
- SupVideo1.gif
Supplementary video 1
- SupVideo2.gif
Supplementary video 2
- SupVideo3.gif
Supplementary video 3
Loading...
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 22 Mar, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Learn more about our company.
This preprint is under consideration at a Nature Portfolio Journal. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Nature journals have partnered with Research Square to offer In Review, a journal-integrated preprint deposition service.
Article
Amir Rosenthal
Technion - Israel Institute of Technology
Corresponding Author
ORCiD: https://orcid.org/0000-0001-8077-7773
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 22 Mar, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Optical imaging is commonly performed with either a camera and wide-field illumination or with a single detector and a collimated beam that scans the imaged object. Unfortunately, sources that can be collimated and cameras do not exist at all wavelengths and may not always achieve the specifications required for a given application. Single-pixel imaging (SPI) offers an alternative that requires a single detector and may be performed with wide-field illumination, potentially enabling imaging applications in which both the detection and illumination technologies are immature. However, SPI currently struggles with low imaging rates owing to its reliance on configurable spatial light modulators, whose rates do not generally exceed 22 kHz. In this work, we develop an approach towards rapid SPI which relies on cyclic patterns coded onto a spinning mask and demonstrate it for in vivo imaging of C. elegans worms. Spatial modulation rates of up to 2.4 MHz and imaging rates of up to 72 fps are reported, creating new opportunities for using the SPI paradigm in dynamic imaging scenarios.
Figure 1
Figure 2
Figure 3
Figure 4
Loading...