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Research Article
Yu Li
West China Hospital of Sichuan University
Corresponding Author
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Complications in anesthesia emergence after neurosurgery varies widely but is associated with negative neurological outcomes. The present study was to investigate postoperative complication in the PACU.
Methods: During July 2015 to July 2016, the retrospective cohort study was conducted and 1586 adult patients who underwent selective neurological surgery in West China Hospital, Sichuan University, were recruited. The complications, including hypertension, hypoxia, etc. were determined by an anesthetist in PACU. Univariate statistics were performed using the chi-squared test, and 95% confidence intervals were determined for the resultant risk ratios. A multivariate model was constructed using significant variables from the univariate analysis (p < 0.05) with binary logistic regression.
Results: Among the involved 1586 patients, the most frequent complications were hypertension (21.5% of patients) and hypoxemia (7.25% of patients), followed by airway obstruction (6.87%). Top three surgery for hypertension incidence were surgery for trigeminal neuralgia, aneurysm, subtentorial lesions. Significant predictors of hypertension included advanced age, sex, preoperative hypertension, and duration of general anesthesia.
Conclusions: In the period of anesthesia recovery of neurosurgical patients, hypertension, hypoxemia, airway obstruction are three main complications in PACU.
Keywords
anesthesia, hypertension, hypoxia, neuralgia, aneurysm
No competing interests reported.
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Reviewer #4 agreed
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Reviewer #10 agreed
On 03 Apr, 2021
Reviewer #1 agreed
On 03 Apr, 2021
Reviewer #9 agreed
On 03 Apr, 2021
Reviewer #2 agreed
On 03 Apr, 2021
Reviewer #3 agreed
On 03 Apr, 2021
Reviewers invited
Invitations sent on 29 Mar, 2021
Editor assigned
On 24 Mar, 2021
Editor invited
On 24 Mar, 2021
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On 24 Mar, 2021
First submitted
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Subject Areas
Anesthesiology & Pain Medicine
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This preprint is under consideration at BMC Anesthesiology. A preprint is a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Yu Li
West China Hospital of Sichuan University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Under Review
Version 1
Posted 25 Mar, 2021
No community comments so far
Review #7 received
Received 03 Apr, 2021
Review #9 received
Received 03 Apr, 2021
Review #8 received
Received 03 Apr, 2021
Review #1 received
Received 03 Apr, 2021
Review #2 received
Received 03 Apr, 2021
Review #3 received
Received 03 Apr, 2021
Reviewer #4 agreed
On 03 Apr, 2021
Reviewer #8 agreed
On 03 Apr, 2021
Reviewer #10 agreed
On 03 Apr, 2021
Reviewer #1 agreed
On 03 Apr, 2021
Reviewer #9 agreed
On 03 Apr, 2021
Reviewer #2 agreed
On 03 Apr, 2021
Reviewer #3 agreed
On 03 Apr, 2021
Reviewers invited
Invitations sent on 29 Mar, 2021
Editor assigned
On 24 Mar, 2021
Editor invited
On 24 Mar, 2021
Submission checks complete
On 24 Mar, 2021
First submitted
On 16 Mar, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Anesthesiology & Pain Medicine
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: Complications in anesthesia emergence after neurosurgery varies widely but is associated with negative neurological outcomes. The present study was to investigate postoperative complication in the PACU.
Methods: During July 2015 to July 2016, the retrospective cohort study was conducted and 1586 adult patients who underwent selective neurological surgery in West China Hospital, Sichuan University, were recruited. The complications, including hypertension, hypoxia, etc. were determined by an anesthetist in PACU. Univariate statistics were performed using the chi-squared test, and 95% confidence intervals were determined for the resultant risk ratios. A multivariate model was constructed using significant variables from the univariate analysis (p < 0.05) with binary logistic regression.
Results: Among the involved 1586 patients, the most frequent complications were hypertension (21.5% of patients) and hypoxemia (7.25% of patients), followed by airway obstruction (6.87%). Top three surgery for hypertension incidence were surgery for trigeminal neuralgia, aneurysm, subtentorial lesions. Significant predictors of hypertension included advanced age, sex, preoperative hypertension, and duration of general anesthesia.
Conclusions: In the period of anesthesia recovery of neurosurgical patients, hypertension, hypoxemia, airway obstruction are three main complications in PACU.
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