In this study, the empirical Bayes method has been applied to a general lifetime model based on the generalized progressive hybrid censored scheme and compared to the fully Bayes method and the maximum likelihood method. The comparisons are made in terms of the root mean squared errors via Monte Carlo simulations. The simulation results are quite favorable to the fully Bayesian model based on the informative prior. However, the empirical Bayes provides better estimates and outperforms the maximum likelihood estimates and the fully Bayes based on the same prior or when there is a wrong choice of the prior hyperparameters. Finally, a numerical example is given to demonstrate the efficiency of the proposed methods.