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Research article
Chuanyong Liu
Jinan Central Hospital Affiliated to Shandong University
Corresponding Author
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Purpose: Dietary carbohydrate intake had become recognized as an important risk factor for risk of esophageal cancer. This meta-analysis aimed to assess the association between dietary carbohydrate intake and the risk of esophageal cancer. Methods: Suitable databases were carefully searched. A random-effects model was used for combined the odds ratio (OR) and 95% confidence interval (CI). Stata software 14.0 was adopted for the analysis. Results: Thirteen publications were included in our study. There was significant correlation between highest category compared with lowest category of dietary carbohydrate intake and the risk of esophageal cancer (summarized OR= 0.627, 95%CI= 0.505-0.778, I2= 59.9%, P for heterogeneity = 0.001). The results in the subgroup of esophageal adenocarcinoma (summarized OR= 0.569, 95%CI= 0.417-0.777) and esophageal squamous cell carcinoma (summarized OR= 0.665, 95%CI= 0.453-0.975) were consistent with the overall result. A positive association was found in European populations, Asian populations, North American populations, instead of South American populations. Conclusions: In conclusions, dietary carbohydrate intake may have a protective effect against the risk of esophageal cancer.
Keywords
Carbohydrate; Dietary; Esophageal cancer; Meta-analysis
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A new preprint design is coming!
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research article
Chuanyong Liu
Jinan Central Hospital Affiliated to Shandong University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
View the published article at Bioscience Reports.
Version 1
Posted 12 Aug, 2019
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at Bioscience Reports.
Purpose: Dietary carbohydrate intake had become recognized as an important risk factor for risk of esophageal cancer. This meta-analysis aimed to assess the association between dietary carbohydrate intake and the risk of esophageal cancer. Methods: Suitable databases were carefully searched. A random-effects model was used for combined the odds ratio (OR) and 95% confidence interval (CI). Stata software 14.0 was adopted for the analysis. Results: Thirteen publications were included in our study. There was significant correlation between highest category compared with lowest category of dietary carbohydrate intake and the risk of esophageal cancer (summarized OR= 0.627, 95%CI= 0.505-0.778, I2= 59.9%, P for heterogeneity = 0.001). The results in the subgroup of esophageal adenocarcinoma (summarized OR= 0.569, 95%CI= 0.417-0.777) and esophageal squamous cell carcinoma (summarized OR= 0.665, 95%CI= 0.453-0.975) were consistent with the overall result. A positive association was found in European populations, Asian populations, North American populations, instead of South American populations. Conclusions: In conclusions, dietary carbohydrate intake may have a protective effect against the risk of esophageal cancer.
Figure 1
Figure 2
Figure 3
Figure 4
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