Prevention Practice and Associated Factors of Coronavirus disease 2019 (COVID-19) Outbreak among Educated Ethiopians: An online Based Cross-sectional Survey

DOI: https://doi.org/10.21203/rs.3.rs-34504/v1

Abstract

Background: An acute respiratory disease, known as the novel coronavirus disease 2019 (COVID-19), was identified in the late 2019. As launched by World Health Organization, it is now a pandemic problem. So far there is no any vaccine or drug for treatment to this disease. The world including Ethiopia have been relying on practicing different preventive measures.  As of 17-Apr-2020, the Ethiopian health minister reported 96 confirmed cases and 3 deaths of COVID-19 from the total of 6231 laboratory tests conducted. The mainstay of approach to avoid COVID-19 is applying preventive measures. Therefore, the current survey aimed to assess self-reported measures of prevention practice and associated factors regarding COVID-19 among educated Ethiopians in the early stage of this outbreak.

Methods: An online based cross-sectional study was conducted to collect information from educated Ethiopians during the early stage of the outbreak from March 25 to April 4, 2020. Electronic based questionnaire developed by reviewing literature and revising from ''COVID-19 Snapshot Monitoring comprised monitoring knowledge, risk perceptions, preventive behaviors, and public trust in the current coronavirus outbreak. Data were analyzed using SPSS-25. Results were presented using descriptive and inferential statistics. To determine predictor variables for preventive practice, a binary logistic regression model was fitted. Variables with a p-value < 0.05 in the final model were declared as predictors.

Results: Five-hundred and twenty-eight Ethiopians participated in this study of which 80.7% were males. The mean age of study participants was 33.2 (±7.4) years. Above one-third (34.7%) of the participants had a health-related profession. Majority (79.7%) of the respondents attended degree and above education. Overall, above half (55.9%) of the study participants had good knowledge about COVID-19. About 55.3% and 57.8% had good knowledge regarding symptoms and prevention methods of COVID-19, respectively. Overall, above half (54%) of the respondents had good COVID-19 preventive practice. Being female [Adjusted Odds Ratio (Adjusted Odds Ratio): 2.00; 95%CI (1.14, 3.50)], higher age (aged 33-37 years [AOR: 1.98; 95%CI (1.01, 3.87)] and 38-72 years [AOR: 2.60; 95%CI (1.33, 5.10)]), good knowledge of symptoms [AOR: 2.82; 95%CI (1.85, 4.31)], good knowledge of prevention methods [AOR: 4.55; 95%CI (2.92, 7.10)], having sufficient knowhow to protect self [AOR: 1.83; 95%CI (1.14, 2.96)] and belief of presence of re-infection [AOR: 1.86; 95%CI (1.03, 3.38)] were significantly associated with COVID-19 preventive practices.

Conclusion: The COVID-19 preventive practice is not sufficiently satisfactory among educated Ethiopians. Females, those with advanced age, those who believes presence of re-infection by COVID-19, those with good knowledge of symptoms, prevention methods, and self-protective knowhow had better preventive practice. Extensive public awareness raising focusing on young population and males is essential to fight further spread of the virus.

Background

Coronavirus disease 2019 (COVID-19) is one of the strain in the family of corona virus  which affects upper respiratory tract (1) An acute respiratory disease, known as the novel coronavirus disease 2019 identified in late 2019. The pathogen responsible for COVID-19 is a member of the coronavirus family, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, also known as the COVID-19 virus (2). The epidemic of unknown acute respiratory tract infection broke out first in Wuhan, China, since 12 December 2019, possibly related to a seafood market but not yet confirmed (3, 4). Suggested ways of human to human transmission of the COVID-19 is through droplet, feco-oral, and direct contact and has an average incubation period of 2-14 days (5).  The disease is characterized by fever, dry cough, fatigue, tiredness and difficulty of breathing (6).

Transmission of SARS occurs primarily among family members, including relatives and friends who have closely encountered patients or carriers of coronavirus (3). On March 17, 2020, the WHO reported that the number of confirmed cases reached 179, 111 and 7426 deaths, the number of confirmed cases in Africa since then been 577 cases (7). In Ethiopia, the first case was reported on 13th March, 2020. On April 5, the number increased to 2 confirmed cases and 2 deaths (8). In response to the COVID-19 outbreak, the Ethiopian government temporarily shut down all schools and cancelled face to face education at higher education institutions.  COVID-19 and its response can also be expected to evoke broader anxieties (9).

The elderly, individuals with serious chronic medical conditions such as heart disease, diabetes mellitus and lung disease are at a higher risk of COVID-19 related death. According to WHO report the case fatality rate in people with no chronic diseases was 1.4 percent, 13.2% for those with cardiovascular disease, 9.2% for diabetes, 8.4% for hypertension, 8.0% for chronic respiratory disease, and 7.6% for cancer (10). There is presently no vaccine or specific anti-viral drug regime used to treat critically ill patients. The management of patients mainly focuses on the provision of supportive care, e.g., oxygenation, ventilation, and fluid management. Combination treatment of low-dose systematic corticosteroids and anti-virals and atomization inhalation of interferon have been encouraged as part of critical COVID-19 management (11). There are also other treatment regimens recommended these days but not yet verified. The main treatment, however is supportive care.

The key components in prevention and control measures and procedures for COVID-19 includes policies and procedures (hand hygiene, staffing, Personal Protective Equipment), routine practices and environmental and housekeeping, transporting patients, screening and surveillance, investigations of outbreaks, frequently wash your hands with soap and water for at least 20 seconds, if no water use an alcohol-based hand rub with at least 60% alcohol ,always wash hands that are visibly soiled, education and training for health care workers, avoid touching eyes, nose, or mouth with unwashed hands point of entry controls, avoid close contact with people who are sick (12-14).  It has paramount effect like depression, anxiety and stress among individuals (15). Old-style public health measures, isolation, social distancing, avoidance of hand shake and community containment, are some of effective methods to prevent a disease when vaccine is not available (16). Millions of people are using different social media to gather information about COVID-19. So knowing preventive practice and factors towards Covid-19 among educated Ethiopians can pay a great role in the prevention of the disease.   Misinformation is a sign of an individual’s failure to inspect and verify the information they are sharing. Ideally, people need to explore the evidence and use empathy before jumping to conclusions, especially where other people and cultures are concerned. One of the challenge in fight against COVID-19 is misinformation and lack of preventive practice.  The battle against COVID-19 is still continuing globally. Assessing preventive practice is an important approach to tackle health problems like Covid-19 among individuals (17, 18). The lessons learned from the 2003 SARS outbreak indicate that good practice towards infectious diseases are related to the degree of fear among the population, which may complicate further efforts to prevent the spread of the disease(19, 20).

The primary objective of this current study is therefore to identify the self-reported preventive practice and associated factors towards Covid-19 among educated Ethiopians using an online data collection by  employing ''COVID-19 Snapshot Monitoring (COSMO): Monitoring knowledge, risk perceptions, preventive behaviours, and public trust in the current coronavirus outbreak" tool.

Methods

Study design, area and period

This online based cross-sectional study design was employed on educated individuals who had been using social media (such as Facebook, electronic mail, and telegram) and currently residing in Ethiopia.  The survey was carried out from March 25 to April 4/ 2020.

Population and inclusion criteria

All educated social media users living in Ethiopia and who are Ethiopian nationals were used as study population. We included all educated social media users who were volunteer to fill the survey.

Sample size determination and sampling technique

It was difficult to determine the minimum sample size for this study. We included all individuals who were volunteer to fill the online survey from March 25 to April 4/ 2020. It was practically difficult to get sufficient response rate in internet based studies and increasing the sample size was essential. So we let the online survey for 10 days active to allow more participants’ involvement.

Operational/term definitions

Variables of the study

Dependent/ outcome variable

Preventive practice about COVID-19

Independent variables

Socio-demographic variables (sex, age, educational status, profession), presence of under-18 years children in house, source of information, self-rated overall health condition, history of psychiatric disease, knowledge about symptoms, prevention methods  and people at higher risk, perceived susceptibility, perceived severity, perception about re-infection by COVID-19, self-rated awareness about COVID-19, primary source of information, and accepting  authorities’ recommendations to prevent COVID-19

Data collection instrument

We used a revised Germany COVID-19 Snapshot Monitoring (COSMO) questionnaire (21) containing socio-demographic variables, knowledge, attitude, and practice about COVID-19 symptoms, transmission routes, incubation period, prevention methods, and misconceptions. The primary variable of interest in this study was preventive practice about COVID-19. The knowledge, attitude and practice were measured as a composite variable computing the responses given for each knowledge, attitude and practice questions respectively.

Data processing and analysis

As this was an online data collection in the form of CSV (excel file), there was no need of data entry. The excel form data were imported into SPSS version 25 for statistical analysis. All assumptions for binary logistic regression were checked.  To determine predictor variables for preventive practice, a binary logistic regression model was fitted.  In multivariable binary logistic regression, variables were considered as significant at a p-value < 0.05. Hosmer and Lemeshow goodness- of -fit test (p>0.05) was used to check model fitness. Results were presented using descriptive and inferential statistics.

Results

Characteristics of study participants

In the current study 528 respondents participated. Four hundred and twenty-six (80.7%) were males and the mean age of the study participants was 33.2 (±7.4) years. Above one-third, 183/528(34.7%) of the participants had a health related profession. Two hundred and thirty-two (43.9%) respondents had at least one child below age 18 years. Most of the study participants (170/528, 32.2%) reported health and health-related institutions as their primary source of information regarding COVID-19 followed by Facebook (138/528, 26.1%). Majority (421/528, 79.7%) of the respondents attended Bachelor degree and above education (table 1).

Table 2 shows the study participants’ overall knowledge, knowledge about groups at high risk to COVID-19, symptoms of the disease, methods of prevention, vaccine none availability, transmission routes, re-infection and incubation period. Overall, above half (295/528, 55.9%) of the study subjects were knowledgeable about COVID-19. One hundred and eighty-three (34.7%) had poor knowledge about people at risk of COVID-19 infection. About 55.3% (292/528) and 57.8% (305/528) had good knowledge regarding symptoms and prevention methods of COVID-19, respectively. The three mostly mentioned symptoms by respondents were fever (96.8%, 511/528), shortness of breath (94.3%, 498/528) and cough (94.1%, 497/528). Nine out of ten (90%, 475/528) respondents know that physical/social distancing can help prevent the spread of COVID-19. Almost all (515/520, 99.04%) know that the disease has no vaccine for prevention or drug developed for treatment yet. Ninety seven point three percent of the respondents know that the disease is transmissible from person to person. While 20.8% (110/528) reported that they did not know whether a person who has recovered from the disease is immune to COVID-19 or not majority (346/528, 65.5%) reported that COVID-19 can re-infect a person who recovered from the illness. Almost all (500/528, 94.7%) respondents reported that the incubation period for the development of symptoms from the time of infection is 14 days.

Table 3 depicts the perception of the respondents regarding probability of getting infected by, susceptibility to, severity if infected with, and acceptance of governmental authority’s recommendation regarding COVID-19. Only one hundred and eighty-one (34.3%) respondents believe that their probability of getting infected is extremely likely. When respondents were asked how severe would contracting the COVID-19 be for them, about two-third (350/528, 66.3%) believe that it would be somewhat severe. Only one-fifth (109/528, 20.6%) and a few number of respondents (22/528, 4.2%) believe that avoiding COVID-19 infection is easy and extremely easy, respectively. While asked whether they follow the recommendations from authorities in their country to prevent spread of COVID-19, only 32% (169/528) responded that they were most likely to adhere to the recommendations. When asked whether they know how to protect themselves from COVID-19, ninety-five participants (18%) responded that they know very much and ten (1.9%) reported that they do not have the know-how at all.

Table 4 shows COVID-19 preventive practice reported by study participants. Overall above half (285/528, 54%) of the respondents had good COVID-19 preventive practice. About nine out of ten (469/528, 88.8%) study subjects reported that they were washing their hands for 20 seconds at 20 minutes intervals. Seventy-five percent (397/528) respondents reported that they have avoided touching their eyes, nose, and mouth with unwashed hands. Two hundred and sixty (49.2%) reported that they have ensured balanced diet to protect themselves from COVID-19 infection. Seventy-three (13.8%) reported that they have avoided consuming meat to protect themselves from COVID-19. About two-fifth (211/528, 40%) reported that they were wearing facemasks. Above one-fourth (139/528, 26.3%) reported that they were consuming a mixture of Ruta chalepensis, ginger, lemon, garlic and honey to protect themselves from COVID-19.  Only 72.9% (385/528) and 36.2 % (191/528) reported that they practiced physical/social distancing and self-quarantine, respectively.

Table 5 shows factors associated with COVID-19 prevention practice. During the bivariable binary logistic regression, sex, age, type of profession, self-rated physical health problem, having a child below 18 years, self-rated awareness about COVID-19, knowledge about people at higher risk of the disease, knowledge of symptoms, prevention methods and re-infection, perceived susceptibility, perceived probability of getting infected, perceived severity, perceived self-protection knowhow, and acceptance of authorities’ recommendations were variables with p-value <0.2. These variables were candidates for the final multivariable binary logistic regression analysis. Variables with p-value<0.05 were declared as significantly associated with the outcome at the final model. Being female, higher age, knowledge of symptoms, knowledge of prevention methods, knowledge of re-infection, and perceived self-protection knowhow were significantly associated with COVID-19 prevention practice.

Females had 2-fold better adjusted odds of COVID-19 prevention practice as compared to males [AOR: 2.00; 95%CI (1.14, 3.50)].

Respondents aged 33-37 years and 38-72 years had 1.99-fold [AOR: 1.98; 95%CI (1.01, 3.87)] and 2.60-fold [AOR: 2.60; 95%CI (1.33, 5.10)] better COVID-19 preventive practice as compared to those aged below 28 years, respectively.

Respondents who have good knowledge of symptoms were 2.82 times [AOR: 2.82; 95%CI (1.85, 4.31)] and those with good knowledge of prevention methods were 4.55 times [AOR: 4.55; 95%CI (2.92, 7.10)] more likely to report better prevention practice as compared to those who have poor knowledge of symptoms and prevention methods, respectively.

Study participants who reported to have sufficient knowhow to protect themselves from COVID-19 had 1.83 times [AOR: 1.83; 95%CI (1.14, 2.96)] better adjusted odds of self-reported prevention practice as compared to those who reported lack of self-protection knowhow.

Respondents who believe that after a person has recovered from the disease, he/she has chance of re-infection had 1.86 [AOR: 1.86; 95%CI (1.03, 3.38)]  times better odds of prevention practice as compared to those who believe that a person after recovery will be immune to COVID-19.

Discussion

To the best of our knowledge, this study which aimed to assess the self-reported prevention practice towards COVID-19 among Ethiopians is the first in the country.  In this study, 54% [95% CI (49.6, 58.5 %)] educated Ethiopians had good self-reported prevention practice towards COVID-19 in the early stage of the outbreak. The self-reported prevention practice towards COVID-19 was good in that 88.8% of the participants wash their hands for at least 20 seconds in 20 minutes interval, 80.5% avoid touching their eyes, nose, and mouth with unwashed hands, and 72.9% practice physical distancing. The possible explanation for this high practice could be the study participants were educated and the first coronavirus case was reported in Ethiopia on 13 March (after 2 months since the first case of COVID-19 was reported from China) and it may increase the dissemination of information which helped them to practice preventive measures. People should practice possible preventive strategies to  protect themselves and others from infection by washing hands or using an alcohol based rub frequently and not touching the face, practicing physical distancing where possible and self-isolate if they start to show symptoms such as fever, tiredness, dry cough, shortness of breath, sore throat, and body aches (22, 23).

The adjusted odds of self-reported prevention practice towards COVID-19 was two-fold higher among female respondents when compared with males. The findings of this study is supported by other study (24). It might be because mostly females participate in childcare, food preparation and other tasks compared with males. Therefore, preventive measures are more likely to be practiced better among females to protect themselves and others from infection.

Respondents aged 33-37 years and 38-72 years had 1.98 and 2.6-fold better practice of COVID-19 preventive measures as compared to those aged below 28 years respectively. Studies on COVID-19 published so far revealed the case fatality rate of  COVID-19 close to 15% in patients over the age of 80 in contrast to the average overall case fatality rate of 2.3% (25) and evidences from China suggested that paediatrics COVID-19 cases might be less severe than cases in adults and that children might experience different symptoms than do adults (26-28). Because of the above scenario, older participants may have better practice of COVID-19 preventive measures than the younger individuals.

When compared respondents who have poor knowledge of COVID-19 symptoms and prevention methods, who have good knowledge of COVID-19 symptoms and prevention methods were 2.82 times and 4.55 times more likely to report better prevention practice respectively. Knowledge of respondents on people at risk group were elderly above 60 years 465 (88.1%), people with pneumonia 412 (78.0%), people with diabetes mellitus 396 (75.0%), people with asthma 396 (75.0%), and people with chronic heart disease 375 (72.0%) from highest to lowest respectively. Knowledge on symptoms of COVID 19 shortness of breath 498 (94.3%), sore throat 447 (84.7%), headache 415 (78.6%), and fatigue 406(76.9%). Knowledge about coronavirus disease (COVID-19) sign and symptoms, transmission, treatment, and how to prevent infection will increase prevention practice of an individuals and they might be implement the key messages of the guideline include causes, how to choose and wear face masks, proper hand washing habits, preventive measures at different locations (e.g., at home, on public transportation, and in public space), disinfection methods, and medical observation at home (24, 29).

Study participants who reported to have sufficient knowhow to protect themselves from COVID-19 had 1.83 times higher better self-reported prevention practice as compared to their counterparts. Knowing the mode of transmission, the prevention mechanism of COVID 19, and the ways of protecting themselves by practicing physical distancing and self-isolation where possible can improve prevention practice.

Respondents who believe that after a person has recovered from the disease, he/she has chance of re-infection had 1.86 times higher better prevention practice as compared to their counterparts. Experts unsure if 'cured' COVID-19 patients are re-infected or relapsed and U.S. experts in a World Health Organization delegation that visited China in February. He said Chinese experts told the visitors that there were no examples of people who became “re-infected”(30). However, there are contradictory reports regarding re-infection which supported the presence of re-infection (31).

Limitations Of The Study

This study was undertaken among educated Ethiopians within a very short period. As this is a cross-sectional study it does not show cause effect relationship. The lack of sufficient literature made the comparison of results difficult.

Conclusion

The COVID-19 preventive practice among educated Ethiopians is not sufficiently satisfactory. Females, those with advanced age, those who believes presence of re-infection by COVID-19, those with good knowledge of symptoms, prevention methods, and self-protective knowhow had better preventive practice. Extensive public awareness raising focusing on young population and males is essential to fight further spread of the virus. Further study on the knowledge, attitude and practice of COVID-19 prevention among uneducated Ethiopians is essential.

Tables

 Table 1: Sociodemographic characteristics of the study participants in Ethiopia (n=528)

Variable

Categories

Frequency (n)

Percentage (%)

Sex

Male

426     

80.7

Female

102     

19.3

Age in years

≤28

135

25.6

29-32

151

28.6

33-37

115

21.8

38-72

127

24.1

Education

Diploma and below

107

20.3

Degree and above

421

79.7

Type of profession

 

Health-related  

183

34.7

Not health-related

345

65.3

Have child under 18 years

Yes

232

43.9

No

296

56.1

Primary source of information

Health and related institutions

170

32.2

Facebook

138

26.1

Government report

87

16.5

TV/radio

84

15.9

Telegram

26

4.9

others

23

4.4

Self-rated overall health condition

Poor

7

1.3

Good

521

98.7

Self-rated physical health problem

No

457

88.6

Yes

71

13.4

Self-reported history of psychiatric disorder

No

505

95.6

Yes

23

4.4

Self-rated knowledge about COVID-19

Poor

22

4.2

Good

506

95.8

Self-rated knowledge about COVID-19 transmission

Poor

25

4.7

Good

503

95.3

 

Table 2: Participants’ knowledge of risky groups, symptoms, prevention methods and preventive practice of COVID-19 among educated Ethiopians (n=528)

Variable

Categories

(n)

(%)

Overall knowledge about COVID- 19

Poor

233

44.1

Good

295

55.9

Knowledge of people at risk group

Poor

183

34.7

Good

345

65.3

Do not know

29

5.5

Elderly above 60 years

465

88.1

Pregnant women

230

43.6

Infants

98

18.6

Children under age five

100

18.9

People with chronic heart disease

375

72.0

People with Diabetes mellitus

396

75.0

People with pneumonia

412

78.0

People with asthma

396

75.0

Knowledge on symptoms

Poor

236

44.7

 

Good

292

55.3

Fever

511

96.8

Cough

497

94.1

Shortness of breath

498

94.3

Sore throat

447

84.7

Runny/stuffy nose

136

25.8

Muscle pain

307

58.1

Headache

415

78.6

Fatigue

406

76.9

Diarrhoea

173

32.8

Knowledge of prevention methods of COVID- 19

Poor

223

42.2

Good

305

57.8

Hand washing for 20 seconds

506

95.8

Avoiding touching your eyes, nose, and mouth with unwashed hands

474

89.8

Use of disinfectants to clean hands when soap and water is not available for washing hands

499

94.5

Staying home when you are sick or when you have a cold

456

86.4

Not travelling abroad

486

92.0

Covering your mouth when you cough

490

92.8

Ensuring a balanced diet

397

75.2

Avoiding close contact with someone who is infected

499

94.5

Avoiding eating meat

114

21.6

Wearing  facemask

424

80.3

Regular physical exercise

309

58.5

Taking mixture of Ruta chalepensis, ginger, lemon, garlic and honey

139

26.3

Taking Areqi (local beer)

32

6.1

Physical/social distancing

475

90.0

Self-quarantine

357

67.6

Knowledge of availability of vaccine and drugs (n=520)

No vaccine and drug

515

99.04

Yes, there is vaccine and drug

5

0.96

Knowledge of transmission route

Do not know

1

0.2

No transmission at all

7

1.3

Only from animal to person transmission

6

1.1

Person to person transmission

514

97.3

Knowledge of re-infection

Do not know

110

20.8

No re-infection

72

13.6

Yes re-infection

346

65.5

Knowledge of incubation period

Do not know

3

0.6

3 days

18

3.4

7 days

7

1.3

14 days

500

94.7

 

Table 3: Attitude towards COVID-19 among educated Ethiopians, 2020 (n=528).

Variable

number (n)

Percentage (%)

Probability of getting infected

 

 

Extremely likely

181     

34.3

Somewhat likely

302     

57.2

Unlikely

37

7.0

Extremely unlikely

8

1.5

Severity if infected

 

 

Very sever

141

26.7

Somewhat sever

350

66.3

Not sever

32

6.1

Not at all sever

5

0.9

Susceptibility 

Extremely susceptible

47

8.9

Highly susceptible

116

22.0

Somewhat susceptible

335

63.4

Not at all susceptible

30

5.7

Self-protection know-how

Very so much

95

18.0

Yes

241

45.6

Somewhat yes

182

34.5

Not at all

10

1.9

How hard is avoiding COVID-19 infection

Extremely easy

22

4.2

Easy

109

20.6

Somewhat difficult

319

60.4

Extremely difficult

78

14.8

How likely do you accept recommendation from authorities

Not at all

3

0.6

Somewhat yes

72

13.6

Yes

284

53.8

Very so much

169

32.0

 

Table 4: Preventive practice of COVID-19 among educated Ethiopians, 2020 (n=528)

Variable

(n)

(%)

Overall preventive practice of COVID-19

Poor

243

46

Good

285

54

Hand washing for 20 seconds at 20 minutes intervals

469

88.8

Avoiding touching your eyes, nose, and mouth with unwashed hands

425

80.5

Use of disinfectants to clean hands when soap and water is not available for washing hands

397

75.2

Staying home when you are sick or when you have a cold

237

44.9

Not travelling abroad

352

66.7

Covering your mouth when you cough

370

70.1

Ensuring a balanced diet

260

49.2

Avoiding close contact with someone who is infected

337

63.8

Avoiding eating meat

73

13.8

Wearing  facemask

211

40.0

Regular physical exercise

160

30.3

Taking mixture of Ruta chalepensis, ginger, lemon, garlic and honey

139

26.3

Taking Areqi (local bear)

38

7.2

Physical/social distancing

385

72.9

Self-quarantine

191

36.2

 

Table 5: Factors associated with COVID-19 prevention practice among Ethiopians (n=528)

 

Variables

COVID-19 prevention practice

COR 95% CI

AOR 95% CI

 

Poor (%)

Good (%)

 

 

Sex 

Female   

34(14.0)

68(23.9)

1.93(1.22,3.03)**

2.00(1.14, 3.50) *

Male        

209(86.0)

217(76.1)

1

1

Age

< 28years

74(30.5)

61(21.4)

1

1

29-32 years

77(31.7)     

74(26.0)

1.17(0.73, 1.86)

0.98(0.56,1.75)

33-37 years

51(21.0) 

64(22.5)

1.52(0.92,2.51)

1.98(1.01,3.87)*

38-72 years

41(16.9) 

86(30.2)

2.54(1.54, 4.21)***

2.60(1.33,5.10) **

Type of profession

Health-related

94(38.7)

89(31.2)

0.72(0.50,1.03)

1.41(0.89,2.23)

Not health-related

149(61.3)

196(68.8)

1

1

Self-rated physical health problem

No       

216(88.9)       

241(84.6)

1

1

Yes    

27(11.1)   

44(15.4)

1.46(0.87,2.44)

0.74(0.39,1.39)

Have   U-18 years children

No     

145(59.7)    

151(53.0)

1

1

Yes    

98(40.3) 

134(47.0)

1.31(0.93, 1.86)

1.09(0.68,1.74)

Self-rated awareness of COVID-19

No 

24(9.9) 

16(5.6)

1

1

Yes    

219(90.1)

269(94.4)

1.84(0.96, 3.56)

0.97(0.43,2.17)

Knowledge of people at higher risk

Poor

96(39.5)

87(30.5)

1

1

Good

147(60.5)

198(69.5)

1.49(1.04,2.13)*

0.97(0.62,1.51)

Knowledge of symptoms

Poor

145(59.7)

91(31.9)

1

1

Good

98(40.3)

194(68.1)

3.15(2.21,4.51)***

2.82(1.85,4.31)***

Knowledge of prevention method

Poor

151(62.1)

72(25.3)

1

1

Good

92(37.9)

213(74.7)

4.86(3.35,7.04)***

4.55(2.92,7.10)***

Primary source of information

Facebook

67(27.6)

71(24.9)

1.41(0.82,2.44)

1.41(0.72,2.73)

Government-report

30(12.3)

57(20)

2.53(1.36,4.70)**

2.00(0.96,4.15)

Health and health-related institutions   

72(29.6) 

98(34.4)

1.82(1.07,3.08)*

1.79(0.95,3.39)

Others*   

15(6.2)  

8(2.8)

0.71(0.27,1.86)

0.55(0.18,1.66)

Telegram

11(4.5)

15(5.3)

1.82(0.75,4.43)

1.78(0.62,5.04)

TV/radio

48(19.8) 

36(12.6)

1

1

Knowledge of re-infection 

No re-infection       

41(16.9)              

31(10.9)

1

1

Do not know

56(23.0)   

54(18.9)

1.28(0.70,2.32)

1.54(0.76,3.13)

Yes re-infection 

146(60.1)

200(70.2)

1.81(1.08,3.03)*

1.86((1.03,3.38)*

Perceived susceptibility

Not susceptible

153(63.0)     

212(74.4)

1.71(1.17,2.48)**

0.86(0.48,1.54)

susceptible

90(37.0)

73(25.6)

1

1

Perceived probability of getting infected

unlikely          

150(61.7)    

197(69.1)

1.39(0.97,1.99)

0.95(0.55,1.64)

likely  

93(383)   

88(30.9)

1

1

Perceived severity

Not sever

23(9.5)   

14(4.9)

1

1

Sever 

220(90.5)

271(95.1)

2.02(1.02,4.03)*

2.06(0.91,4.70)

Perceived self-protection know-how

No    

114(46.9)     

78(27.4)

1

1

Yes     

129(53.1)   

207(72.6)

2.34(1.63,3.37)***

1.83(1.14,2.96)*

Acceptance of authorities recommendations

No

48(19.8)       

27(9.5)

1

1

Yes      

195(80.2)   

258(90.5)

2.35(1.42,3.90)*

1.22(0.62,2.39)

1= Reference group, * Significant at p < 0.05, ** p<0.01,  *** Significant at p < 0.001, Hosmer  and Lemeshow goodness of fit test (p=0.881)

Abbreviations

AOR: Adjusted Odds Ratio CI: Confidence Interval COR: Crude Odds Ratio EPI Info: Epidemiological Information SPSS: Statistical Package for Social Sciences

Declarations

Ethical approval and consent to participate

Ethical approval was obtained from the Ethical Review Committee of Environmental and Occupational Health and Safety department, the University of Gondar. Respondents were communicated via social media. After explaining the purpose of the study, respondents were asked to fill and submit their responses. Any potential identifiers were eliminated to ascertain confidentiality.

Consent for publication

Not applicable

Availability of data and materials

The dataset is accessible at the corresponding author upon a reasonable request.

Competing interests

The authors declare that they have no competing interests

Funding

No funding agent

Authors’ contributions

 HD participated as a lead investigator in conceptualization, proposal development, analysis and write up of the manuscript, KA, DT, AMA, ZA, BD, DEA and JA write various parts of the proposal and the manuscript, help in analysis and commented the draft and final manuscript. All authors reviewed and approved the final manuscript.

Acknowledgments

The authors are grateful for study participants, University of Gondar, individuals and associations who helped in dissemination of the data collection tool. We are grateful to Hakim-page, Journalists (Ayalew Menber, Metages Ayelegn, Amdework Nigussie, Solomon Muche), Natnael Mekonnen, Deacon Birhanu Admas Aniley and Kesis Dejene Shiferaw for their unreserved support to make this research work a reality.

References

  1. Joseph T. COVID-19: International pulmonologist’s consensus group on COVID-19; 2020 [Available from: https://www.unah.edu.hn/dmsdocument/9674-consenso-internacional-de-neumologos-sobre-covid-19-version-ingles.
  2. Lipsitch M, Swerdlow DL, Finelli L. Defining the epidemiology of Covid-19—studies needed. New England Journal of Medicine. 2020.
  3. Guo Y-R, Cao Q-D, Hong Z-S, Tan Y-Y, Chen S-D, Jin H-J, et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak–an update on the status. Military Medical Research. 2020;7(1):1-10.
  4. Paraskevis D, Kostaki EG, Magiorkinis G, Panayiotakopoulos G, Sourvinos G, Tsiodras S. Full-genome evolutionary analysis of the novel corona virus (2019-nCoV) rejects the hypothesis of emergence as a result of a recent recombination event. Infection, Genetics and Evolution. 2020;79:104212.
  5. Bhagavathula AS, Aldhaleei WA, Rahmani J, Mahabadi MA, Bandari DK. Novel Coronavirus (COVID-19) Knowledge and Perceptions: A Survey on Healthcare workers. medRxiv. 2020.
  6. Wu Z, McGoogan JM. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: summary of a report of 72 314 cases from the Chinese Center for Disease Control and Prevention. Jama. 2020.
  7. WHO. Coronavirus disease (COVID-2019) situation reports: Situation report - 57. 2020.
  8. apanews.net. Ethiopia reports sixth case of coronavirus. . 2020.
  9. Leach M. Echoes of Ebola: social and political warnings for the COVID-19 response in African settings. Echoes. 2020.
  10. Canady VA. Mental health groups providing support, education in wake of COVID‐19. Mental Health Weekly. 2020;30(11):1-3.
  11. Liu Y, Li J, Feng Y. Critical care response to a hospital outbreak of the 2019-nCoV infection in Shenzhen, China. BioMed Central; 2020.
  12. Liu C, Zhou Q, Li Y, Garner LV, Watkins SP, Carter LJ, et al. Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases. ACS Publications; 2020.
  13. Ono SJ. COVID-19 and Faculty of Medicine Preparedness.
  14. Bai Y, Yao L, Wei T, Tian F, Jin D-Y, Chen L, et al. Presumed asymptomatic carrier transmission of COVID-19. Jama. 2020.
  15. Wang C, Pan R, Wan X, Tan Y, Xu L, Ho CS, et al. Immediate psychological responses and associated factors during the initial stage of the 2019 coronavirus disease (COVID-19) epidemic among the general population in china. International Journal of Environmental Research and Public Health. 2020;17(5):1729.
  16. Wilder-Smith A, Freedman D. Isolation, quarantine, social distancing and community containment: pivotal role for old-style public health measures in the novel coronavirus (2019-nCoV) outbreak. Journal of travel medicine. 2020;27(2):taaa020.
  17. Ajilore K, Atakiti I, Onyenankeya K. College students’ knowledge, attitudes and adherence to public service announcements on Ebola in Nigeria: Suggestions for improving future Ebola prevention education programmes. Health Education Journal. 2017;76(6):648-60.
  18. Tachfouti N, Slama K, Berraho M, Nejjari C. The impact of knowledge and attitudes on adherence to tuberculosis treatment: a case-control study in a Moroccan region. Pan African Medical Journal. 2012;12(1).
  19. Person B, Sy F, Holton K, Govert B, Liang A. Fear and stigma: the epidemic within the SARS outbreak. Emerging Infectious Diseases. 2004;10(2):358.
  20. Zhong B-L, Luo W, Li H-M, Zhang Q-Q, Liu X-G, Li W-T, et al. Knowledge, attitudes, and practices towards COVID-19 among Chinese residents during the rapid rise period of the COVID-19 outbreak: a quick online cross-sectional survey. Int J Biol Sci. 2020;16(10):1745-52.
  21. Betsch C, Wieler L, Bosnjak M, Ramharter M, Stollorz V, Omer S, et al. Germany COVID-19 Snapshot MOnitoring (COSMO Germany): Monitoring knowledge, risk perceptions, preventive behaviours, and public trust in the current coronavirus outbreak in Germany. 2020.
  22. Plan for international. What is coronavirus / COVID-19? 2020 [cited 2020 10. April]. Available from: https://plan-international.org/emergencies/covid-19-faqs-girls-women
  23. Organization WH. Key Messages and Actions for COVID-19 Prevention and Control in Schools. 2020.
  24. Zhong B-L, Luo W, Li H-M, Zhang Q-Q, Liu X-G, Li W-T, et al. Knowledge, attitudes, and practices towards COVID-19 among Chinese residents during the rapid rise period of the COVID-19 outbreak: a quick online cross-sectional survey. International Journal of Biological Sciences. 2020;16(10):1745.
  25. Healthline. Older or with underlying conditions at greatest risk 2020 [cited 2020 April, 10]. Available from: https://www.healthline.com/health-news/what-older-people-with-chronic-conditions-need-to-know-about-covid-19.
  26. Center of communical disease control. Coronavirus Disease 2019 in Children — United States, February 12–April 2, 2020 2020 [cited 2020 April, 2020]. Available from: https://www.cdc.gov/mmwr/volumes/69/wr/mm6914e4.htm.
  27. Lu X, Zhang L, Du H, Zhang J, Li YY, Qu J, et al. SARS-CoV-2 Infection in Children. New England Journal of Medicine. 2020.
  28. Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, et al. Epidemiology of COVID-19 Among Children in China. Pediatrics. 2020:e20200702.
  29. Adhikari SP, Meng S, Wu Y-J, Mao Y-P, Ye R-X, Wang Q-Z, et al. Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: a scoping review. Infectious diseases of poverty. 2020;9(1):1-12.
  30. Snopses. Can People Who Recover from COVID-19 Become Reinfected? 2020 [cited 2020 April 10,]. Available from: https://www.snopes.com/fact-check/covid-19-reinfection/.
  31. Kelly S. Covid-19 re-infection rates increase 2020 [cited 2020 April 9]. Available from: https://thethaiger.com/coronavirus/cv19-asia/cv19-thailand/covid-19-reinfection-rates-increase.