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Research
Wenxian Guan
Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital
Corresponding Author
ORCiD: https://orcid.org/0000-0001-5210-1485
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background: It is well established that retrieved lymph nodes (RLNs) count were positively correlated with better overall survival in gastric cancer (GC). But little is known about the relationship between RLNs count and short-term complications after radical surgery.
Methods: A total of 1487 consecutive GC patients between January 2016 and December 2018 at Nanjing Drum Tower Hospital were retrospectively analyzed. Univariate analyses were performed to elucidate the association between RLNs count and postoperative complications. We further identified clinical factors that might affect the RLNs count.
Results: Among all of the patients, postoperative complications occurred in 435 (29.3%) patients. The mean RLNs count was 25.1 and 864 (58.1%) patients were diagnosed with lymph node metastasis. Univariate analyses showed no significant difference between RLNs count and postoperative complications (both overall and stratified by CDC grade). Univariate and multivariate analyses further revealed that type of resection, tumor invasion, and lymph node metastasis were associated with RLNs count.
Conclusions: The current study demonstrated that RLNs count was not associated with postoperative short-term complications following gastrectomy of GC, which provided a rationale for the determination of a proper RLNs count of curative gastrectomy.
Keywords
Retrieved lymph nodes, Postoperative complications, Gastric cancer
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CURRENT STATUS: Published
View the published article at World Journal of Surgical Oncology.
Version 3
Posted 17 Aug, 2020
No community comments so far
Editorial decision: Accept
On 12 Aug, 2020
Editor assigned
On 11 Aug, 2020
Submission checks complete
On 10 Aug, 2020
Editor invited
On 10 Aug, 2020
No comments provided
Editorial decision: Minor Revision
On 10 Aug, 2020
Review #2 received
Received 09 Aug, 2020
Reviewer #2 agreed
On 06 Aug, 2020
Review #1 received
Received 05 Aug, 2020
Reviewer #1 agreed
On 03 Aug, 2020
Reviewers invited
Invitations sent on 03 Aug, 2020
Editor assigned
On 02 Aug, 2020
Submission checks complete
On 01 Aug, 2020
Editor invited
On 01 Aug, 2020
No comments provided
Editorial decision: Major Revision
On 09 Jul, 2020
Review #1 received
Received 06 Jul, 2020
Reviewer #2 agreed
On 24 Jun, 2020
Review #2 received
Received 24 Jun, 2020
Reviewer #1 agreed
On 13 Jun, 2020
Reviewers invited
Invitations sent on 12 Jun, 2020
First submitted
On 09 Jun, 2020
Editor assigned
On 09 Jun, 2020
Submission checks complete
On 08 Jun, 2020
Editor invited
On 08 Jun, 2020
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Learn more about our company.
A new preprint design is coming!
We have improved readability, clarity, accessibility, and opportunities for engagement.
See the published version of this preprint at World Journal of Surgical Oncology.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research
Wenxian Guan
Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital
Corresponding Author
ORCiD: https://orcid.org/0000-0001-5210-1485
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at World Journal of Surgical Oncology.
Version 3
Posted 17 Aug, 2020
No community comments so far
Editorial decision: Accept
On 12 Aug, 2020
Editor assigned
On 11 Aug, 2020
Submission checks complete
On 10 Aug, 2020
Editor invited
On 10 Aug, 2020
No comments provided
Editorial decision: Minor Revision
On 10 Aug, 2020
Review #2 received
Received 09 Aug, 2020
Reviewer #2 agreed
On 06 Aug, 2020
Review #1 received
Received 05 Aug, 2020
Reviewer #1 agreed
On 03 Aug, 2020
Reviewers invited
Invitations sent on 03 Aug, 2020
Editor assigned
On 02 Aug, 2020
Submission checks complete
On 01 Aug, 2020
Editor invited
On 01 Aug, 2020
No comments provided
Editorial decision: Major Revision
On 09 Jul, 2020
Review #1 received
Received 06 Jul, 2020
Reviewer #2 agreed
On 24 Jun, 2020
Review #2 received
Received 24 Jun, 2020
Reviewer #1 agreed
On 13 Jun, 2020
Reviewers invited
Invitations sent on 12 Jun, 2020
First submitted
On 09 Jun, 2020
Editor assigned
On 09 Jun, 2020
Submission checks complete
On 08 Jun, 2020
Editor invited
On 08 Jun, 2020
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at World Journal of Surgical Oncology.
Background: It is well established that retrieved lymph nodes (RLNs) count were positively correlated with better overall survival in gastric cancer (GC). But little is known about the relationship between RLNs count and short-term complications after radical surgery.
Methods: A total of 1487 consecutive GC patients between January 2016 and December 2018 at Nanjing Drum Tower Hospital were retrospectively analyzed. Univariate analyses were performed to elucidate the association between RLNs count and postoperative complications. We further identified clinical factors that might affect the RLNs count.
Results: Among all of the patients, postoperative complications occurred in 435 (29.3%) patients. The mean RLNs count was 25.1 and 864 (58.1%) patients were diagnosed with lymph node metastasis. Univariate analyses showed no significant difference between RLNs count and postoperative complications (both overall and stratified by CDC grade). Univariate and multivariate analyses further revealed that type of resection, tumor invasion, and lymph node metastasis were associated with RLNs count.
Conclusions: The current study demonstrated that RLNs count was not associated with postoperative short-term complications following gastrectomy of GC, which provided a rationale for the determination of a proper RLNs count of curative gastrectomy.
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