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Research Article
Wen-Zheng Li
Central South University
Corresponding Author
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Background To analyze the differences in clinical features and computed tomography characteristics in the two types of mixed epithelial and stromal tumor of the kidney (MESTK) and to establish a treatment plan for the MESTK types.
Methods 17 patients underwent multidetector computed tomography (MDCT) before surgery and had a pathological diagnosis of MESTK were enrolled. Their clinical information (R.E.N.A.L.Nephrometry Score (R.E.N.A.L.－NS), radical nephrectomy (RN), partial nephrectomy (PN), etc.) were collected. The radiological features included renal sinus fat invagination (SFI), maximal diameter (MD), capsule and septa of the tumor, etc. were also analyzed. They were divided into two types according to the MDsolid/MDtumor ratio (type A with > 63%; type B with ≤ 63%). An independent-sample t-test and Fisher exact test were used to assess the differences between the two groups.
Results MESTKs demonstrated a variable multi-septate cystic and solid components with a delayed enhancement. There were 9 patients for type A and 8 subjects for type B. Compared with type A, the lesions in type B have larger MD (79.13±39.06 vs. 41.22±24.19, p = 0.028), higher R.E.N.A.L.－NS (10.03±0.50 vs. 8.95±1.26, P＜0.001), higher RN (75.00% vs.22.22%, p =0.015), larger SFI (87.5% vs.33.3%, p=0.05), more septa (100% vs. 0%, p <0.001) and more capsule (100% vs. 11.1%, p < 0.001).
Conclusion Type B MESTK has more hazardous features compared with type A, suggesting that RN is more suitable for type B and PN for type A.
Keywords
mixed epithelial and stromal tumor of the kidney, multidetector computed tomography features, clinical data, patient management, classification
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No competing interests reported.
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A new preprint design is coming!
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This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Research Article
Wen-Zheng Li
Central South University
Corresponding Author
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
History
CURRENT STATUS: Posted
Version 1
Posted 02 Apr, 2021
No community comments so far
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
Background To analyze the differences in clinical features and computed tomography characteristics in the two types of mixed epithelial and stromal tumor of the kidney (MESTK) and to establish a treatment plan for the MESTK types.
Methods 17 patients underwent multidetector computed tomography (MDCT) before surgery and had a pathological diagnosis of MESTK were enrolled. Their clinical information (R.E.N.A.L.Nephrometry Score (R.E.N.A.L.－NS), radical nephrectomy (RN), partial nephrectomy (PN), etc.) were collected. The radiological features included renal sinus fat invagination (SFI), maximal diameter (MD), capsule and septa of the tumor, etc. were also analyzed. They were divided into two types according to the MDsolid/MDtumor ratio (type A with > 63%; type B with ≤ 63%). An independent-sample t-test and Fisher exact test were used to assess the differences between the two groups.
Results MESTKs demonstrated a variable multi-septate cystic and solid components with a delayed enhancement. There were 9 patients for type A and 8 subjects for type B. Compared with type A, the lesions in type B have larger MD (79.13±39.06 vs. 41.22±24.19, p = 0.028), higher R.E.N.A.L.－NS (10.03±0.50 vs. 8.95±1.26, P＜0.001), higher RN (75.00% vs.22.22%, p =0.015), larger SFI (87.5% vs.33.3%, p=0.05), more septa (100% vs. 0%, p <0.001) and more capsule (100% vs. 11.1%, p < 0.001).
Conclusion Type B MESTK has more hazardous features compared with type A, suggesting that RN is more suitable for type B and PN for type A.
Figure 1
Figure 2
Figure 3
Figure 4
Figure 5
No competing interests reported.
This is a list of supplementary files associated with this preprint. Click to download.
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