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Brief Communication
David Gloriam
University of Copenhagen
Corresponding Author
ORCiD: https://orcid.org/0000-0002-4299-7561
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We present an online, interactive platform for comparative analysis of all available G protein-coupled receptor structures while correlating to functional data. The comprehensive platform encompasses structure similarity, secondary structure, protein backbone packing and movement, residue-residue contact networks, amino acid properties and prospective design of experimental mutagenesis studies. This lets any researcher tap the potential of sophisticated structural analyses enabling a plethora of basic and applied research studies.
Keywords
Interactive Platform, Functional Data, Sophisticated Structural Analyses, Applied Research Studies
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The full text of this article is available to read as a PDF.
There is NO Competing Interest.
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Learn more about our company.
A new preprint design is coming!
We have improved readability, clarity, accessibility, and opportunities for engagement.
See the published version of this preprint at Nature Structural & Molecular Biology.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Brief Communication
David Gloriam
University of Copenhagen
Corresponding Author
ORCiD: https://orcid.org/0000-0002-4299-7561
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at Nature Structural & Molecular Biology.
Version 1
Posted 01 Apr, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at Nature Structural & Molecular Biology.
We present an online, interactive platform for comparative analysis of all available G protein-coupled receptor structures while correlating to functional data. The comprehensive platform encompasses structure similarity, secondary structure, protein backbone packing and movement, residue-residue contact networks, amino acid properties and prospective design of experimental mutagenesis studies. This lets any researcher tap the potential of sophisticated structural analyses enabling a plethora of basic and applied research studies.
Figure 1
Figure 2
The full text of this article is available to read as a PDF.
There is NO Competing Interest.
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