The study focused analyzing the determinants of honey supply, to analyze the economy of beekeeping, honey marketing and income generating activities undertaken in Horo Guduru wollega zone of Oromia Region, Ethipia. About 121 honey producers (110 male & 11 female) were selected randomly from a list of 536 honey producers found in 5 purposively selected ‘kebeles’. The data were generated by individual interview and group discussions using pre-tested semi structured questionnaires and checklists. Secondary data were collected from different published and unpublished sources. The data collected were analyzed with the help of descriptive statistics and econometric model (multiple linear regression model). The results obtained from econometric analysis indicates that colony size, type of beehives used, beekeeping equipment, market information, current honey price, frequency of extension contact per year and trainings were positively and significantly affected honey supply. Of course, some opportunities have also been indicated like availability of bee colony, favorable environment, and annual flora and farmers’ experiences. To boost the economy of beekeeping and honey marketing which in turn increase producers income from honey supply, all concerned bodies need to focus on building farmers capacity via training on improving honey production and supply, increasing access to improved beehives and its accessories, availing extension facilities, improving road facility, organizing honey producers to increase the volume, access to marketing and price setting, and establishing honey market center are recommended for policy intervention.