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Research Article
Wenbo Xu
Chinese Center for Disease Control and Prevention
Corresponding Author
ORCiD: https://orcid.org/0000-0001-5911-8837
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During 2017–2018, Nasopharyngeal aspirates (NPAs) from 627 hospitalized patients with SARI at Luohe Center Hospital were tested by RT-PCR for human parainfluenza virus 4(HPIV-4). 14 (2.2%) of 627 samples were positive for HPIV-4. The complete nucleotide sequence of the HN gene from 9 positive samples was amplified and sequenced successfully. Genetic analysis showed that the HPIV-4 strains circulating in Luohe city are more closely related to HPIV-4A. Our study indicated that there were multiple lineages of HPIV-4 circulating in Henan Province in China during the study period, which will improve our understanding of the epidemiological and clinical characteristics of HPIV-4.
Keywords
Nasopharyngeal Aspirates, Genetic Analysis, Epidemiological and Clinical Characteristics
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View the published article at Archives of Virology.
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A new preprint design is coming!
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See the published version of this preprint at Archives of Virology.
This is a preprint, a preliminary version of a manuscript that has not completed peer review at a journal. Research Square does not conduct peer review prior to posting preprints. The posting of a preprint on this server should not be interpreted as an endorsement of its validity or suitability for dissemination as established information or for guiding clinical practice.
Learn more about In Review
Research Article
Wenbo Xu
Chinese Center for Disease Control and Prevention
Corresponding Author
ORCiD: https://orcid.org/0000-0001-5911-8837
Badges
Prescreen
This manuscript passed our Prescreen assessment
Complete author information
Appropriate declaration statements
Potential risks to human health
Prescreen
Peer Review Timeline
CURRENT STATUS: Published
View the published article at Archives of Virology.
Version 1
Posted 05 Apr, 2021
No community comments so far
Reviewers invited
Invitations sent on 31 Mar, 2021
Editor assigned
On 28 Mar, 2021
First submitted
On 24 Mar, 2021
Metrics
Comments: 0
PDF Downloads: ...
HTML Views: ...
Subject Areas
Virology
License:
This work is licensed under a CC BY 4.0 License. Read Full License
View the published article at Archives of Virology.
During 2017–2018, Nasopharyngeal aspirates (NPAs) from 627 hospitalized patients with SARI at Luohe Center Hospital were tested by RT-PCR for human parainfluenza virus 4(HPIV-4). 14 (2.2%) of 627 samples were positive for HPIV-4. The complete nucleotide sequence of the HN gene from 9 positive samples was amplified and sequenced successfully. Genetic analysis showed that the HPIV-4 strains circulating in Luohe city are more closely related to HPIV-4A. Our study indicated that there were multiple lineages of HPIV-4 circulating in Henan Province in China during the study period, which will improve our understanding of the epidemiological and clinical characteristics of HPIV-4.
Figure 1
Figure 2
This is a list of supplementary files associated with this preprint. Click to download.
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