Exposure and response prevention (ERP) is a form of cognitive behavioral therapy (CBT) that can effectively relieve obsessive-compulsive symptoms and tic symptoms in patients with obsessive-compulsive disorder (OCD) and Tourette syndrome (TS). However, the effect size of ERP is still unclear.
In this study, we performed a meta-analysis to identify the efficacy of ERP for individuals with OCD and TS. The standard mean difference (SMD) with a 95% confidence interval (CI) was calculated to assess the effect size of the efficacy for ERP. We used subgroup and meta-regression analysis to explore the heterogeneity of the pooled SMD of ERP for OCD.
A total of 17 studies including a total of 926 patients with OCD and 66 patients with TS were identified. We observed a small-to-medium effect size of ERP for both OCD (SMD = -0.21, 95% CI: -0.47 to 0.06) and TS (SMD = -0.26, 95% CI: -0.75 to 0.22).
In conclusion, we found that ERP is effective for patients with OCD and TS. We suggest a combination with other therapies and the development of online ERP services that might prove a promising new direction for healthcare providers.
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Posted 30 Jul, 2020
Posted 30 Jul, 2020
Exposure and response prevention (ERP) is a form of cognitive behavioral therapy (CBT) that can effectively relieve obsessive-compulsive symptoms and tic symptoms in patients with obsessive-compulsive disorder (OCD) and Tourette syndrome (TS). However, the effect size of ERP is still unclear.
In this study, we performed a meta-analysis to identify the efficacy of ERP for individuals with OCD and TS. The standard mean difference (SMD) with a 95% confidence interval (CI) was calculated to assess the effect size of the efficacy for ERP. We used subgroup and meta-regression analysis to explore the heterogeneity of the pooled SMD of ERP for OCD.
A total of 17 studies including a total of 926 patients with OCD and 66 patients with TS were identified. We observed a small-to-medium effect size of ERP for both OCD (SMD = -0.21, 95% CI: -0.47 to 0.06) and TS (SMD = -0.26, 95% CI: -0.75 to 0.22).
In conclusion, we found that ERP is effective for patients with OCD and TS. We suggest a combination with other therapies and the development of online ERP services that might prove a promising new direction for healthcare providers.
Figure 1
Figure 2
Figure 3
Figure 4
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