The main theme of this paper is to analyze the effects of concentric catheterization to the diseased arterial segment having both stenosis and aneurysm along its boundary. Fractional second grade hybrid nanofluid model is under consideration. Governing equations are formulated and further linearized for both cases of mild stenosis and aneurysm. Precise articulations for various important flow characteristics heat transfer, hemodynamic velocity, wall shear stress and resistance impedance are attained. Graphical portrayals for the impact of the significant parameters on the flow attributes have been devised and talked about. The worldwide conduct of blood has been examined using an instantaneous streamlines pattern. The present concept plans to be of use in medical regime for the drug conveyance system and biomedicines.